Sliding mode control for a diffuse interface tumor growth model coupling a Cahn–Hilliard equation with a reaction–diffusion equation

2020 ◽  
Vol 43 (10) ◽  
pp. 6598-6626
Author(s):  
Michele Colturato
2016 ◽  
Vol 28 (2) ◽  
pp. 284-316 ◽  
Author(s):  
HARALD GARCKE ◽  
KEI FONG LAM

We consider a diffuse interface model for tumour growth consisting of a Cahn–Hilliard equation with source terms coupled to a reaction–diffusion equation. The coupled system of partial differential equations models a tumour growing in the presence of a nutrient species and surrounded by healthy tissue. The model also takes into account transport mechanisms such as chemotaxis and active transport. We establish well-posedness results for the tumour model and a variant with a quasi-static nutrient. It will turn out that the presence of the source terms in the Cahn–Hilliard equation leads to new difficulties when one aims to derivea prioriestimates. However, we are able to prove continuous dependence on initial and boundary data for the chemical potential and for the order parameter in strong norms.


1996 ◽  
Vol 7 (3) ◽  
pp. 287-301 ◽  
Author(s):  
J. W. Cahn ◽  
C. M. Elliott ◽  
A. Novick-Cohen

We show by using formal asymptotics that the zero level set of the solution to the Cahn–Hilliard equation with a concentration dependent mobility approximates to lowest order in ɛ. an interface evolving according to the geometric motion,(where V is the normal velocity, Δ8 is the surface Laplacian and κ is the mean curvature of the interface), both in the deep quench limit and when the temperature θ is where є2 is the coefficient of gradient energy. Equation (0.1) may be viewed as motion by surface diffusion, and as a higher-order analogue of motion by mean curvature predicted by the bistable reaction-diffusion equation.


Author(s):  
Mohammad Ramezani

AbstractThe main propose of this paper is presenting an efficient numerical scheme to solve WSGD scheme for one- and two-dimensional distributed order fractional reaction–diffusion equation. The proposed method is based on fractional B-spline basics in collocation method which involve Caputo-type fractional derivatives for $$0 < \alpha < 1$$ 0 < α < 1 . The most significant privilege of proposed method is efficient and quite accurate and it requires relatively less computational work. The solution of consideration problem is transmute to the solution of the linear system of algebraic equations which can be solved by a suitable numerical method. The finally, several numerical WSGD Scheme for one- and two-dimensional distributed order fractional reaction–diffusion equation.


Author(s):  
Oluwaseun Adeyeye ◽  
Ali Aldalbahi ◽  
Jawad Raza ◽  
Zurni Omar ◽  
Mostafizur Rahaman ◽  
...  

AbstractThe processes of diffusion and reaction play essential roles in numerous system dynamics. Consequently, the solutions of reaction–diffusion equations have gained much attention because of not only their occurrence in many fields of science but also the existence of important properties and information in the solutions. However, despite the wide range of numerical methods explored for approximating solutions, the adoption of block methods is yet to be investigated. Hence, this article introduces a new two-step third–fourth-derivative block method as a numerical approach to solve the reaction–diffusion equation. In order to ensure improved accuracy, the method introduces the concept of nonlinearity in the solution of the linear model through the presence of higher derivatives. The method obtained accurate solutions for the model at varying values of the dimensionless diffusion parameter and saturation parameter. Furthermore, the solutions are also in good agreement with previous solutions by existing authors.


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