Reactions of chlorogenic acid and quercetin with a soy protein isolate – Influence on the in vivo food protein quality in rats

2006 ◽  
Vol 50 (8) ◽  
pp. 696-704 ◽  
Author(s):  
Sascha Rohn ◽  
Klaus J. Petzke ◽  
Harshadrai M. Rawel ◽  
Jürgen Kroll
2008 ◽  
Vol 24 (6) ◽  
pp. 503-526 ◽  
Author(s):  
Li-Hua Luo ◽  
Yu-Feng Zhang ◽  
Xiao-Mei Wang ◽  
Yu Wan ◽  
Peter R. Chang ◽  
...  

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Zijian Wang ◽  
MeiFang Ke ◽  
Liu He ◽  
Qi Dong ◽  
Xiao Liang ◽  
...  

Abstract Innovative biomedical applications have high requirements for biomedical materials. Herein, a series of biocompatible, antibacterial and hemostatic sponges were successfully fabricated for the treatment of acute upper gastrointestinal bleeding (AUGB). Quaternized chitosan (QC) and soy protein isolate (SPI) were chemically cross-linked to obtain porous SPI/QC sponges (named SQS-n, with n = 30, 40, 50 or 60 corresponding to the weight percentage of the QC content). The chemical composition, physical properties and biological activity of SQS-n were investigated. SQS-n could support the adhesion and proliferation of L929 cells while triggering no obvious blood toxicity. Meanwhile, SQS-n exhibited good broad-spectrum antibacterial activity against both gram-positive bacteria (Staphylococcus aureus) and gram-negative bacteria (Escherichia coli). The in vivo hemostatic effect of SQS-n was evaluated using three different bleeding models. The results revealed that SQS-50 performed best in reducing blood loss and hemostatic time. The overall hemostatic effect of SQS-50 was comparable to that of a commercial gelatin sponge. The enhanced antibacterial and hemostatic activities of SQS-n were mainly attributed to the QC component. In conclusion, this work developed a QC-functionalized hemostatic sponge that is highly desirable for innovative biomedical applications, such as AUGB.


2000 ◽  
Vol 43 (6) ◽  
pp. 633-648 ◽  
Author(s):  
E. Saggau ◽  
M. Beyer ◽  
M. Klein ◽  
R. Schadereit ◽  
M. Derno ◽  
...  

Abstract. To estimate long-term effects of dietary protein quality on energy metabolism and thyroid hormone Status in growing pigs two experiments were carried out, each using 6 growing German Landrace barrows (40 to 90 kg body weight (BW)) per treatment group, which were fed semisynthetic isoenergetic diets based on either casein or soy protein isolate at 1875 kJ ME/(kg BW0,62 x d). Casein was tested with (CAS+) amino acid (AA) supplementation (methionine + cystine, threonine, tryptophane) and soy protein isolate was tested without (SPI-) AA supplementation at the recommended protein supply of 100% (normal protein level (NP)) and at a protein supply of 50% of NP. During experiments pigs were housed individually in metabolic cages at 23 ± 1 °C. At both protein supply levels, SP1- in comparison to CAS+ caused a lower protein energy retention (PER), which was compensated mainly by an increased fat energy retention (FER). The reduction of the protein supply to 50% caused a lower PER by 30 to 50% in both dietary qualities, which was compensated by a significantly higher FER. However, the heat production (HP) was neither affected by the protein quality nor by the quantity, and resulted in nearly similar values of 60% of ME intake. The thyroid hormone concentrations were dependent primarily on the amount of protein supply, and after decrease of supply to 50% secondly on the dietary protein quality. The increased thyroid hormone concentrations at the 50% protein level were in euthyroid range of pigs and obviously not associated with HP.


RSC Advances ◽  
2016 ◽  
Vol 6 (96) ◽  
pp. 93275-93287 ◽  
Author(s):  
Jovita Kanoujia ◽  
Mahendra Singh ◽  
Pooja Singh ◽  
Poonam Parashar ◽  
Chandra Bhusan Tripathi ◽  
...  

Lipid lowering potential of soy protein isolate and whey protein concentrate as novel nanomaterial for atorvastatin nanoparticles.


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