Technical Note: Quality assurance of proton central axis pencil‐beam spread‐out Bragg peak using large‐diameter multilayer ionization chambers

2019 ◽  
Vol 46 (10) ◽  
pp. 4685-4689 ◽  
Author(s):  
Peng Wang ◽  
Mingyao Zhu ◽  
Katja Langen
Keyword(s):  
Quality Assurance ◽  
Bragg Peak ◽  
Large Diameter ◽  
Technical Note ◽  
Central Axis ◽  
Pencil Beam ◽  
Ionization Chambers ◽  
Spread Out Bragg Peak

scholarly journals Commissioning of GPU–Accelerated Monte Carlo Code FRED for Clinical Applications in Proton Therapy

2021 ◽  
Vol 8 ◽  
Author(s):  
Jan Gajewski ◽  
Magdalena Garbacz ◽  
Chih-Wei Chang ◽  
Katarzyna Czerska ◽  
Marco Durante ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Quality Assurance ◽  
Treatment Planning ◽  
Propagation Model ◽  
Beam Model ◽  
Monte Carlo Code ◽  
Pencil Beam ◽  
Ionization Chambers ◽  
Passing Rate ◽  
Gamma Index

We present commissioning and validation of Fred, a graphical processing unit (GPU)–accelerated Monte Carlo code, for two proton beam therapy facilities of different beam line design: CCB (Krakow, IBA) and EMORY (Atlanta, Varian). We followed clinical acceptance tests required to approve the certified treatment planning system for clinical use. We implemented an automated and efficient procedure to build a parameter library characterizing the clinical proton pencil beam. Beam energy, energy spread, lateral propagation model, and a dosimetric calibration factor were parametrized based on measurements performed during the facility start-up. The Fred beam model was validated against commissioning and supplementary measurements performed with and without range shifter. We obtained 1) submillimeter agreement of Bragg peak shapes in water and lateral beam profiles in air and slab phantoms, 2) <2% dose agreement for spread out Bragg peaks of different ranges, 3) average gamma index (2%/2 mm) passing rate of >95% for >1000 patient verification measurements using a two-dimensional array of ionization chambers, and 4) gamma index passing rate of >99% for three-dimensional dose distributions computed with Fred and measured with an array of ionization chambers behind an anthropomorphic phantom. The results of example treatment planning study on >100 patients demonstrated that Fred simulations in computed tomography enable an accurate prediction of dose distribution in patient and application of Fred as second patient quality assurance tool. Computation of a patient treatment in a CT using 104 protons per pencil beam took on average 2′30 min with a tracking rate of 2.9×105p+/s. Fred was successfully commissioned and validated against the clinical beam model, showing that it could potentially be used in clinical routine. Thanks to high computational performance due to GPU acceleration and an automated beam model implementation method, the application of Fred is now possible for research or quality assurance purposes in most of the proton facilities.

scholarly journals Investigating the Implications of a Variable RBE on Proton Dose Fractionation Across a Clinical Pencil Beam Scanned Spread-Out Bragg Peak

2016 ◽  
Vol 95 (1) ◽  
pp. 70-77 ◽  
Author(s):  
Thomas I. Marshall ◽  
Pankaj Chaudhary ◽  
Anna Michaelidesová ◽  
Jana Vachelová ◽  
Marie Davídková ◽  
...  
Keyword(s):  
Bragg Peak ◽  
Dose Fractionation ◽  
Pencil Beam ◽  
Proton Dose ◽  
Spread Out Bragg Peak

Relative biological effectiveness in a proton spread-out Bragg peak formed by pencil beam scanning mode

2017 ◽  
Vol 40 (2) ◽  
pp. 359-368 ◽  
Author(s):  
Anna Michaelidesová ◽  
Jana Vachelová ◽  
Monika Puchalska ◽  
Kateřina Pachnerová Brabcová ◽  
Vladimír Vondráček ◽  
...  
Keyword(s):  
Bragg Peak ◽  
Relative Biological Effectiveness ◽  
Pencil Beam ◽  
Beam Scanning ◽  
Pencil Beam Scanning ◽  
Biological Effectiveness ◽  
Spread Out Bragg Peak

Technical Note: Validation of halo modeling for proton pencil beam spot scanning using a quality assurance test pattern

2015 ◽  
Vol 42 (9) ◽  
pp. 5138-5143 ◽  
Author(s):  
Liyong Lin ◽  
Sheng Huang ◽  
Minglei Kang ◽  
Timothy D. Solberg ◽  
James E. McDonough ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Test Pattern ◽  
Technical Note ◽  
Pencil Beam ◽  
Beam Spot ◽  
Spot Scanning

Applications of a novel detector for pencil beam scanning proton therapy beam quality assurance

2021 ◽  
pp. 2140041
Author(s):  
Pei-Ying Yang ◽  
Yang-Wei Hsieh ◽  
Chen-Lin Kang ◽  
Chin-Dar Tseng ◽  
Chih-Hsueh Lin ◽  
...  
Keyword(s):  
Quality Assurance ◽  
Proton Therapy ◽  
Beam Quality ◽  
Beam Width ◽  
Scanning Speed ◽  
Spot Size ◽  
Pencil Beam ◽  
Beam Position ◽  
The Cross ◽  
One Year

This study utilized a new type of detector, the CROSS II (Liverage Biomedical Inc., Taiwan), to perform a beam quality assurance (QA) procedure on a Sumitomo (Sumitomo Heavy Industries, Inc., Japan) pencil beam linear scanning proton therapy machine. The Cross II can monitor proton Pristine Bragg peak range, beam width, beam size, beam position, and scanning speed. All the data presented here were collected during a time span of over one year. The accuracy of the QA program could be verified if all the QA items were tested stably and within the programmed tolerances. Our results showed that the proton range remained within the [Formula: see text] mm tolerance, with the majority of measurements within [Formula: see text] mm, [Formula: see text] mm for spot size, 1.5 mm for spot position, and [Formula: see text]% for scanning speed. We found that the CROSS II detector is in high precise and steady state with highly efficient. Our proton therapy system was also proven to be in an accurate and reliable condition according to our QA results.

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