scholarly journals Age and gender dependence of human cardiac phosphorus metabolites determined by SLOOP31P MR spectroscopy

2006 ◽  
Vol 56 (4) ◽  
pp. 907-911 ◽  
Author(s):  
Herbert Köstler ◽  
Wilfried Landschütz ◽  
Sabrina Koeppe ◽  
Tobias Seyfarth ◽  
Claudia Lipke ◽  
...  
Keyword(s):  
Mr Spectroscopy ◽  
Age And Gender ◽  
And Gender ◽  
Phosphorus Metabolites ◽  
Gender Dependence

Area, Age and Gender Dependence of the Nucleoside System in the Brain: a Review of Current Literature

2011 ◽  
Vol 11 (8) ◽  
pp. 1012-1033 ◽  
Author(s):  
Zsolt Kovacs ◽  
Gabor Juhasz ◽  
Miklos Palkovits ◽  
Arpad Dobolyi ◽  
Katalin A. Kekesi
Keyword(s):  
Current Literature ◽  
Age And Gender ◽  
And Gender ◽  
Gender Dependence ◽  
The Brain

scholarly journals Calcitonin measurement in pediatrics: reference ranges are gender-dependent, validation in medullary thyroid cancer and thyroid diseases

2019 ◽  
Vol 57 (8) ◽  
pp. 1242-1250 ◽  
Author(s):  
Felix Eckelt ◽  
Mandy Vogel ◽  
Mandy Geserick ◽  
Toralf Kirsten ◽  
Yoon Ju Bae ◽  
...  
Keyword(s):  
Reference Intervals ◽  
Thyroid Diseases ◽  
Reference Ranges ◽  
Limited Information ◽  
Serum Samples ◽  
Age And Gender ◽  
Medullary Thyroid ◽  
Men 2 ◽  
And Gender ◽  
Gender Dependence

Abstract Background There is only limited information on serum reference ranges of calcitonin (CT) in infants, children and adolescents. This gap hampers valid diagnostics in patients with multiple endocrine neoplasia type 2 (MEN 2) and planned prophylactic thyroidectomy. In addition, age-dependent reference ranges for CT are necessary to define a cure in medullary thyroid carcinoma (MTC). We asked whether the reference ranges for CT levels were age- and gender-dependent in the serum of a pediatric cohort. Methods A total of 6090 serum samples of 2639 subjects of the LIFE-Child cohort aged between 1 month and 17.9 years were analyzed by the CT electrochemiluminescence immunoassay (ECLIA). Reference intervals were estimated using the LMS method. For clinical validation the serum of 28 patients (61 samples) with MEN 2 and 106 patients (136 samples) with thyroid diseases were analyzed. Results CT levels showed a clear age- and gender-dependence with significantly higher values in boys (p<0.01). An accelerated decline of CT levels from newborn to children at the age of 4 and 5 years was observed for both sexes. A cure for MTC was demonstrated in 71% of MEN 2 patients after thyroidectomy, whereas 5 patients remained suspicious for micrometastasis or relapse. Only 1.5% of our patients with thyroid diseases revealed increased CT levels. Conclusions This is the largest study to establish novel pediatric reference ranges from the CT values of healthy subjects. It allows a precise laboratory monitoring of CT in pediatric patients with MEN 2. Thyroid diseases did not have a relevant influence on CT levels in our pediatric cohort.

Age and Gender Dependence of Maximum Forced Expiratory Tracheal Collapse in Healthy Subjects.

2009 ◽  
Author(s):  
CR O'Donnell ◽  
PM Boiselle ◽  
A Bankier ◽  
M Pollock ◽  
A Potemkin ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Age And Gender ◽  
And Gender ◽  
Tracheal Collapse ◽  
Gender Dependence

scholarly journals Age and gender dependence of pre-contrast T1-relaxation times in normal human myocardium at 1.5T using ShMOLLI

2012 ◽  
Vol 14 (S1) ◽  
Author(s):  
Stefan K Piechnik ◽  
Vanessa Ferreira ◽  
Adam J Lewandowski ◽  
Ntobeko Ntusi ◽  
Daniel Sado ◽  
...  
Keyword(s):  
Relaxation Times ◽  
Human Myocardium ◽  
Age And Gender ◽  
T1 Relaxation ◽  
Normal Human ◽  
And Gender ◽  
Gender Dependence

scholarly journals Age and gender dependence of liver diffusion parameters and the evidence of intravoxel incoherent motion modelling of perfusion component is constrained by diffusion component

2020 ◽  
Author(s):  
Hua Huang ◽  
Cun-Jing Zheng ◽  
Li-Fei Wang ◽  
Nazmi Che-Nordin ◽  
Yì Xiáng J. Wáng
Keyword(s):  
Spin Echo ◽  
Liver Perfusion ◽  
B Value ◽  
Single Shot ◽  
Age And Gender ◽  
Age Related ◽  
Diffusion Component ◽  
And Gender ◽  
Echo Type ◽  
Gender Dependence

AbstractObjectivesTo establish reference values for middle aged subjects and investigate age and gender dependence of liver diffusion MRI parameters.MethodsThe IVIM type of liver diffusion scan was based on a single-shot spin-echo type echo-planar sequence using a 1.5-T magnet with 16 b-values. DDVD (diffusion-derived vessel density) was the signal difference between b=0 and b=2 s/mm2 images after removing visible vessels. IVIM analysis was performed with full-fitting and segmented-fitting, and with threshold b-value of 60 or 200 s/mm2, and fitting started from b=2 s/mm2. 32 men (age range: 25-71 years) and 26 men (age: 22-69 years) had DDVD and IVIM analysis respectively, while 36 women (age: 20-71 years) had DDVD and IVIM analysis.ResultsDDVD had an age-related reduction noted for women. IVIM results of full fitting had good agreement with segmented fitting with threshold b of 60 s/mm2 results, but less so with results of threshold b of 200 s/mm2. As age increases, female subjects’ Dslow measure had significant reduction, and PF and Dfast measure had significant increase. For the age group of 40-55 years, DDVD, Dslow, PF, and Dfast were 12.27±3.90, 1.072±0.067 (10−3mm2/s), 0.141±0.025, 61.0±14.0 (10−3mm2/s), and 13.4±3.6, 1.069±0.074 mm2/s, 0.119±0.014, 57.1±13.2 mm2/s, for men and women, respectively.ConclusionDDVD measure suggest that aging may be associated with reduction in liver perfusion. Lower Dslow measurement can lead to artificial higher PF and Dfast measurement, providing the evidence of IVIM modeling of perfusion component is constrained by diffusion component.

scholarly journals Assessing the age- and gender-dependence of the severity and case fatality rates of COVID-19 disease in Spain

2020 ◽  
Vol 5 ◽  
pp. 117 ◽  
Author(s):  
Paula Moraga ◽  
David I. Ketcheson ◽  
Hernando C. Ombao ◽  
Carlos M. Duarte
Keyword(s):  
Disease Onset ◽  
Case Fatality ◽  
Health Resources ◽  
Age Group ◽  
Age And Gender ◽  
And Gender ◽  
Using Data ◽  
Gender Dependence ◽  
Inform Decision Making ◽  
Different Levels

Background: The assessment of the severity and case fatality rates of coronavirus disease 2019 (COVID-19) and the determinants of its variation is essential for planning health resources and responding to the pandemic. The interpretation of case fatality rates (CFRs) remains a challenge due to different biases associated with surveillance and reporting. For example, rates may be affected by preferential ascertainment of severe cases and time delay from disease onset to death. Using data from Spain, we demonstrate how some of these biases may be corrected when estimating severity and case fatality rates by age group and gender, and identify issues that may affect the correct interpretation of the results. Methods: Crude CFRs are estimated by dividing the total number of deaths by the total number of confirmed cases. CFRs adjusted for preferential ascertainment of severe cases are obtained by assuming a uniform attack rate in all population groups, and using demography-adjusted under-ascertainment rates. CFRs adjusted for the delay between disease onset and death are estimated by using as denominator the number of cases that could have a clinical outcome by the time rates are calculated. A sensitivity analysis is carried out to compare CFRs obtained using different levels of ascertainment and different distributions for the time from disease onset to death. Results: COVID-19 outcomes are highly influenced by age and gender. Different assumptions yield different CFR values but in all scenarios CFRs are higher in old ages and males. Conclusions: The procedures used to obtain the CFR estimates require strong assumptions and although the interpretation of their magnitude should be treated with caution, the differences observed by age and gender are fundamental underpinnings to inform decision-making.

scholarly journals Male brain ages faster: the age and gender dependence of subcortical volumes

2015 ◽  
Vol 10 (3) ◽  
pp. 901-910 ◽  
Author(s):  
András Király ◽  
Nikoletta Szabó ◽  
Eszter Tóth ◽  
Gergő Csete ◽  
Péter Faragó ◽  
...  
Keyword(s):  
Age And Gender ◽  
And Gender ◽  
Gender Dependence ◽  
Subcortical Volumes
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