Whole‐brain amide CEST imaging at 3T with a steady‐state radial MRI acquisition

2021 ◽  
Vol 86 (2) ◽  
pp. 893-906 ◽  
Author(s):  
Ran Sui ◽  
Lin Chen ◽  
Yuguo Li ◽  
Jianpan Huang ◽  
Kannie W. Y. Chan ◽  
...  
Keyword(s):  
Steady State ◽  
Whole Brain ◽  
Cest Imaging ◽  
Radial Mri

Snapshot whole-brain T1relaxometry using steady-state prepared spiral multislice variable flip angle imaging

2017 ◽  
Vol 79 (2) ◽  
pp. 856-866 ◽  
Author(s):  
Rahel Heule ◽  
Josef Pfeuffer ◽  
Oliver Bieri
Keyword(s):  
Steady State ◽  
Flip Angle ◽  
Variable Flip Angle ◽  
Whole Brain

scholarly journals Exploring the dynamic mechanisms of steady-state visual evoked potentials at the whole-brain level: evidence from a computational study

2021 ◽  
Author(s):  
Ge Zhang ◽  
Yan Cui ◽  
Yangsong Zhang ◽  
Hefei Cao ◽  
Guanyu Zhou ◽  
...  
Keyword(s):  
Steady State ◽  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Large Scale ◽  
Whole Brain ◽  
Frequency Sensitivity ◽  
Dynamic Mechanisms ◽  
Brain Level ◽  
The Brain ◽  
Visual Evoked

AbstractPeriodic visual stimulation can induce stable steady-state visual evoked potentials (SSVEPs) distributed in multiple brain regions and has potential applications in both neural engineering and cognitive neuroscience. However, the underlying dynamic mechanisms of SSVEPs at the whole-brain level are still not completely understood. Here, we addressed this issue by simulating the rich dynamics of SSVEPs with a large-scale brain model designed with constraints of neuroimaging data acquired from the human brain. By eliciting activity of the occipital areas using an external periodic stimulus, our model was capable of replicating both the spatial distributions and response features of SSVEPs that were observed in experiments. In particular, we confirmed that alpha-band (8-12 Hz) stimulation could evoke stronger SSVEP responses; this frequency sensitivity was due to nonlinear resonance and could be modulated by endogenous factors in the brain. Interestingly, the stimulus-evoked brain networks also exhibited significant superiority in topological properties near this frequency-sensitivity range, and stronger SSVEP responses were demonstrated to be supported by more efficient functional connectivity at the neural activity level. These findings not only provide insights into the mechanistic understanding of SSVEPs at the whole-brain level but also indicate a bright future for large-scale brain modeling in characterizing the complicated dynamics and functions of the brain.

Whole-brain perfusion imaging with balanced steady-state free precession arterial spin labeling

2015 ◽  
Vol 29 (3) ◽  
pp. 264-274 ◽  
Author(s):  
Paul Kyu Han ◽  
Jong Chul Ye ◽  
Eung Yeop Kim ◽  
Seung Hong Choi ◽  
Sung-Hong Park
Keyword(s):  
Steady State ◽  
Perfusion Imaging ◽  
Arterial Spin Labeling ◽  
Steady State Free Precession ◽  
Brain Perfusion ◽  
Spin Labeling ◽  
Free Precession ◽  
Whole Brain ◽  
Brain Perfusion Imaging

scholarly journals Linearization Correction of 99mTc-Labeled Hexamethyl-Propylene Amine Oxime (HM-PAO) Image in Terms of Regional CBF Distribution: Comparison to C15O2 Inhalation Steady-State Method Measured by Positron Emission Tomography

1988 ◽  
Vol 8 (1_suppl) ◽  
pp. S52-S60 ◽  
Author(s):  
Atsushi Inugami ◽  
Iwao Kanno ◽  
Kazuo Uemura ◽  
Fumio Shishido ◽  
Matsutaro Murakami ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Steady State ◽  
Emission Tomography ◽  
Emission Computed Tomography ◽  
Whole Brain ◽  
Steady State Method ◽  
Positron Emission ◽  
State Method

The radioisotope distribution following intravenous injection of 99mTc-labeled hexamethylpropyleneamine oxime (HM-PAO) in the brain was measured by single photon emission computed tomography (SPECT) and corrected for the nonlinearity caused by differences in net extraction. The “linearization” correction was based on a three compartment model, and it required a region of reference to normalize the SPECT image in terms of regional cerebral blood flow distribution. Two different regions of reference, the cerebellum and the whole brain, were tested. The uncorrected and corrected HM-PAO images were compared with cerebral blood flow (CBF) image measured by the C15O2 inhalation steady state method and positron emission tomography (PET). The relationship between uncorrected HM-PAO and PET–CBF showed a correlation coefficient of 0.85 but tended to saturate at high CBF values, whereas it was improved to 0.93 after the “linearization” correction. The whole-brain normalization worked just as well as normalization using the cerebellum. This study constitutes a validation of the “linearization” correction and it suggests that after linearization the HM-PAO image may be scaled to absolute CBF by employing a global hemispheric CBF value as measured by the nontomographic 133Xe clearance method.

scholarly journals Whole brain inhomogeneous magnetization transfer (ihMT) imaging: Sensitivity enhancement within a steady‐state gradient echo sequence

2017 ◽  
Vol 79 (5) ◽  
pp. 2607-2619 ◽  
Author(s):  
Samira Mchinda ◽  
Gopal Varma ◽  
Valentin H. Prevost ◽  
Arnaud Le Troter ◽  
Stanislas Rapacchi ◽  
...  
Keyword(s):  
Steady State ◽  
Magnetization Transfer ◽  
Sensitivity Enhancement ◽  
Gradient Echo ◽  
Whole Brain ◽  
Inhomogeneous Magnetization

Whole‐brain steady‐state CEST at 3 T using MR Multitasking

2021 ◽  
Author(s):  
Pei Han ◽  
Karandeep Cheema ◽  
Hsu‐Lei Lee ◽  
Zhengwei Zhou ◽  
Tianle Cao ◽  
...  
Keyword(s):  
Steady State ◽  
Whole Brain

scholarly journals 3D isotropic high-resolution diffusion-weighted MRI of the whole brain with a motion-corrected steady-state free precession sequence

2012 ◽  
Vol 70 (2) ◽  
pp. 466-478 ◽  
Author(s):  
R. L. O'Halloran ◽  
M. Aksoy ◽  
A. T. Van ◽  
R. Bammer
Keyword(s):  
Steady State ◽  
High Resolution ◽  
Steady State Free Precession ◽  
Diffusion Weighted Mri ◽  
Free Precession ◽  
Whole Brain ◽  
Diffusion Weighted

Optimization of steady-state pulsed CEST imaging for amide proton transfer at 3T MRI

2019 ◽  
Vol 81 (6) ◽  
pp. 3616-3627 ◽  
Author(s):  
Byungjai Kim ◽  
Seohee So ◽  
Hyunwook Park
Keyword(s):  
Steady State ◽  
Proton Transfer ◽  
Amide Proton ◽  
3T Mri ◽  
Amide Proton Transfer ◽  
Cest Imaging
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