Depositional Models of Deep-Water Gravity-Flow in Lacustrine Basin and Its Petroleum Geological Significance—A Case Study of Chang 6 Oil Group in Heshui Area, Ordos Basin, China

Gravity-flow can carry a large number of sediments and organic matters from shallow water to deep lakes with its strong transporting energy, directly or indirectly facilitating the formation of deep-water tight reservoirs and shale reservoirs. Therefore, studying the genetic types, dynamic mechanisms, and depositional models of gravity-flow deposits is essential in the exploration of unconventional petroleum in large lacustrine basins. This research studied the genetic types, dynamic mechanisms, and sedimentary models of the gravity-flow deposits of the Chang 6 oil group in the Heshui Area, Ordos Basin, China, aiming to reveal its petroleum geological significance. Core observation, microscopic thin section identification, particle size analysis, and determination of rare earth elements were carried out. As a result, three types of gravity-flow deposits are detected, namely, slide-slump, sandy debris flow, and turbidity current. A certain slope gradient in bed form is the necessary geomorphic condition for gravity flow formation, and determines its development level, distribution range, and flow transformation efficiency. Sufficient provenance lays the material foundation and determines its depositional composition and development type. Other factors include earthquakes, volcanoes, and floods, which serve as triggering forces. In addition, fragmentation, liquefaction, and fluid mixing are the main dynamic mechanisms driving flow transformation. Based on the flow type of gravity flow, particle size characteristics, gravity-flow transformation relations, development mechanism, and spatial distribution pattern, we distinguished two depositional gravity-flow models, i.e., slump turbidite body and sublacustrine fan. Re-portrait the spatial distribution of deep-water gravity flow in the study area. From the perspective of sedimentology, explain the genesis of sand bodies in the northeast and southwest. The sandy debris flow in the middle fan braided channel microfacies of the sublacustrine fan sways the development of thick massive sand bodies in the study area. Hybrid event beds formed by the fluid transformation in a slump turbidite are the potential dessert area for deep-water tight oil and gas.

Precise control of microtubule disassembly in living cells

Microtubules (MTs) are components of the evolutionarily conserved cytoskeleton, which tightly regulates various cellular activities. Our understanding of MTs is largely based on MT-targeting agents, which, however, are insufficient to dissect the dynamic mechanisms of specific MT populations due to their slow effects on the entire pool of MTs in cells. To address this limitation, we have used chemogenetics and optogenetics to disassemble specific MT subtypes by rapid recruitment of engineered MT-cleaving enzymes. Acute MT disassembly swiftly halted vesicular trafficking and lysosome dynamics. We also used this approach to disassemble MTs specifically modified by tyrosination and several MT-based structures including primary cilia, mitotic spindles, and intercellular bridges. These effects were rapidly reversed by inhibiting the activity or MT association of the cleaving enzymes. The disassembly of targeted MTs with spatial and temporal accuracy enables to uncover new insights of how MTs precisely regulate cellular architectures and functions.

Comparative analysis of electromechanical processes in induction-dynamic converter with mobile inductor and two disks

General description of the research topic. The article presents a comprehensive study of traditional induction-dynamic mechanisms (with one disk and a fixed coil) and multi-core induction-dynamic mechanisms (linear pulse induction converters) with a movable coil and two disks. Actuality of the topic. Such induction-dynamic mechanisms are widely used in various fields, in particular, in electrical apparatus industry, where speed is one of the most important characteristics. The purpose of the article is a comparative analysis and refinement of the characteristics of the traditional induction-dynamic system with one disk and a fixed coil and multi-core one with a movable coil and two disks. Research method, scientific novelty. The calculations are based on the solution of the equations of the electromagnetic field and the equations for the electric circuit of the coil. Practical significance and main conclusions. During the calculations, the values of electromagnetic force and force impulse acting on the moving disk, energy losses in the system and electromagnetic energy of the system are determined. The results of the study are presented in the form of graphs, namely, the coil current and total magnetic energy for a traditional induction-dynamic mechanism with one disk and for multi-core one with two disks, Joule losses in a fixed coil and disk (in a traditional system) and in a moving coil and two disks (in a multi-core system), force impulse and electromagnetic force of a moving coil (in a multi-core system) and a moving disk (in a traditional and a multi-core system) total impulse of the moving parts of the induction-dynamic mechanism with a multi-core system, as well as the electromagnetic force and the total force acting on the moving parts of the induction-dynamic mechanism with a multi-core system. It is shown that the induction-dynamic mechanism with two disks is less effective in terms of electromagnetic force, impulse and electromagnetic energy than the induction-dynamic mechanism of the traditional layout.

Digital media and misinformation: An outlook on multidisciplinary strategies against manipulation

This review discusses the dynamic mechanisms of misinformation creation and spreading used in social networks. It includes: (1) a conceptualization of misinformation and related terms, such as rumors and disinformation; (2) an analysis of the cognitive vulnerabilities that hinder the correction of the effects of an inaccurate narrative already assimilated; and (3) an interdisciplinary discussion on different strategies for coping with misinformation. The discussion encompasses journalistic, educational, governmental and computational viewpoints on the topic. The review also surveys how digital platforms handle misinformation and gives an outlook on opportunities to address it in light of the presented viewpoints.

Yeast volatiles double starvation survival in Drosophila

Organisms make decisions based on the information they gather from their environment, the effects of which affect their fitness. Understanding how these interactions affect physiology may generate interventions that improve the length and quality of life. Here, we provide evidence that exposure to live yeast volatiles during starvation significantly extends survival, increases activity, and slows the rate of triacylglyceride (TAG) decline independent of canonical sensory perception. We demonstrate that ethanol (EtOH) is one of the active components in yeast volatiles that influences these phenotypes and that EtOH metabolites mediate dynamic mechanisms to promote Drosophila survival. Silencing R4d neurons reverses the ability of high EtOH concentrations to promote starvation survival, and their activation promotes EtOH metabolism. The transcription factor foxo promotes EtOH resistance, likely by protection from EtOH toxicity. Our results suggest that food-related cues recruit neural circuits and modulate stress signaling pathways to promote survival during starvation.