Patient engagement in the design of an intervention to prevent muscle loss in individuals with knee osteoarthritis and a body mass index (BMI) ≥ 35

2021 ◽  
Author(s):  
Kristine Godziuk ◽  
Carla Prado ◽  
Mary Forhan
2011 ◽  
Vol 71 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Andrew K Wills ◽  
Stephanie Black ◽  
Rachel Cooper ◽  
Russell J Coppack ◽  
Rebecca Hardy ◽  
...  

IntroductionThe authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA.MethodsA population-based British birth cohort of 3035 men and women underwent clinical examination for knee OA at age 53 years.Heights and weights were measured 10 times from 2 to 53 years. Analyses were stratified by gender and adjusted for occupation and activity levels.ResultsThe prevalence of knee OA was higher in women than in men (12.9% (n=194) vs 7.4% (n=108)). In men, the association between BMI and later knee OA was evident at 20 years (p=0.038) and remained until 53 years (OR per z-score 1.38 (95% CI 1.11 to 1.71)). In women, there was evidence for an association at 15 years (p=0.003); at 53 years, the OR was 1.89 (95% CI 1.59 to 2.24) per z-score increase in BMI. Changes in BMI from childhood in women and from adolescence in men were also positively associated with knee OA. A structured modelling approach to disentange the way in which BMI is linked to knee OA suggested that prolonged exposure to high BMI throughout adulthood carried the highest risk and that there was no additional risk conferred from adolescence once adult BMI had been accounted for.ConclusionThis study suggests that the risk of knee OA accumulates from exposure to a high BMI through adulthood.


2017 ◽  
Vol 69 (8) ◽  
pp. 1266-1270 ◽  
Author(s):  
Adam G. Culvenor ◽  
David T. Felson ◽  
Jingbo Niu ◽  
Wolfgang Wirth ◽  
Martina Sattler ◽  
...  

2019 ◽  
Vol 27 ◽  
pp. S368 ◽  
Author(s):  
I.P. Munugoda ◽  
D.A. Aitken ◽  
W. Wirth ◽  
F. Eckstein

2017 ◽  
Vol 15 (3) ◽  
pp. 307-312 ◽  
Author(s):  
Fábio Marcon Alfieri ◽  
Natália Cristina de Oliveira Vargas e Silva ◽  
Linamara Rizzo Battistella

ABSTRACT Objective To assess the influence of the body weight in functional capacity and pain of adult and elderly individuals with knee osteoarthritis. Methods The sample consisted of 107 adult and elderly patients with knee osteoarthritis divided into two groups (adequate weight/adiposity and excessive weight/adiposity) according to body mass index and percent of body fat mass, assessed by electric bioimpedance. Subjects were evaluated for functional mobility (Timed Up and Go Test), pain, stiffness and function (Western Ontario and MacMaster Universities Osteoarthritis Index − WOMAC), pain intensity (Visual Analogue Scale − VAS) and pressure pain tolerance threshold (algometry in vastus medialis and vastus lateralis muscles). Data were analyzed with Statistical Package of the Social Sciences, version 22 for Windows. Comparisons between groups were made through Student’s t test, with significance level set at 5%. Results There was predominance of females in the sample (81.3%), and mean age was 61.8±10.1 years. When dividing the sample by both body mass index and adiposity, 89.7% of them had weight/adiposity excess, and 59.8% were obese. There was no difference between groups regarding age, pain intensity, pressure pain tolerance threshold, functional mobility, stiffness and function. However, pain (WOMAC) was higher (p=0.05) in the group of patients with weight or adiposity excess, and pain perception according to VAS was worse in the group of obese patients (p=0.05). Conclusion Excessive weight had negative impact in patients with osteoarthritis, increasing pain assessed by WOMAC or VAS, although no differences were observed in functionality and pressure pain tolerance.


Author(s):  
A Veenbrink ◽  
F Kroon ◽  
R de Mutsert ◽  
W Visser ◽  
S le Cessie ◽  
...  

2009 ◽  
Vol 36 (9) ◽  
pp. 1987-1990 ◽  
Author(s):  
AMANDA E. NELSON ◽  
LARISSA BRAGA ◽  
ANDRESA BRAGA-BAIAK ◽  
JULIUS ATASHILI ◽  
TODD A. SCHWARTZ ◽  
...  

Objective.To determine if knee alignment measures differ between African Americans and Caucasians without radiographic knee osteoarthritis (rOA).Methods.A single knee was randomly selected from 175 participants in the Johnston County Osteoarthritis Project without rOA in either knee. Anatomic axis, condylar, tibial plateau, and condylar plateau angles were measured by 1 radiologist; means were compared and adjusted for age and body mass index (BMI).Results.There were no significant differences in knee alignment measurements between Caucasians and African Americans among men or women.Conclusion.Observed differences in knee rOA occurrence between African Americans and Caucasians are not explained by differences in static knee alignment.


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