scholarly journals Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study

2011 ◽  
Vol 71 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Andrew K Wills ◽  
Stephanie Black ◽  
Rachel Cooper ◽  
Russell J Coppack ◽  
Rebecca Hardy ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Knee Osteoarthritis ◽  
Birth Cohort ◽  
Body Mass ◽  
Prolonged Exposure ◽  
Birth Cohort Study ◽  
Activity Levels ◽  
Z Score ◽  
Knee Oa ◽  
High Bmi

IntroductionThe authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA.MethodsA population-based British birth cohort of 3035 men and women underwent clinical examination for knee OA at age 53 years.Heights and weights were measured 10 times from 2 to 53 years. Analyses were stratified by gender and adjusted for occupation and activity levels.ResultsThe prevalence of knee OA was higher in women than in men (12.9% (n=194) vs 7.4% (n=108)). In men, the association between BMI and later knee OA was evident at 20 years (p=0.038) and remained until 53 years (OR per z-score 1.38 (95% CI 1.11 to 1.71)). In women, there was evidence for an association at 15 years (p=0.003); at 53 years, the OR was 1.89 (95% CI 1.59 to 2.24) per z-score increase in BMI. Changes in BMI from childhood in women and from adolescence in men were also positively associated with knee OA. A structured modelling approach to disentange the way in which BMI is linked to knee OA suggested that prolonged exposure to high BMI throughout adulthood carried the highest risk and that there was no additional risk conferred from adolescence once adult BMI had been accounted for.ConclusionThis study suggests that the risk of knee OA accumulates from exposure to a high BMI through adulthood.

scholarly journals Maternal pre-pregnancy body mass index explains infant's weight and BMI at 14 months: results from a multi-ethnic birth cohort study

2009 ◽  
Vol 94 (8) ◽  
pp. 587-595 ◽  
Author(s):  
I Mesman ◽  
T J Roseboom ◽  
G J Bonsel ◽  
R J Gemke ◽  
M F van der Wal ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Birth Cohort ◽  
Body Mass ◽  
Birth Cohort Study

scholarly journals Do the associations of body mass index and waist circumference with back pain change as people age? 32 years of follow-up in a British birth cohort

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e039197
Author(s):  
Stella Muthuri ◽  
Rachel Cooper ◽  
Diana Kuh ◽  
Rebecca Hardy
Keyword(s):  
Body Mass Index ◽  
Back Pain ◽  
Waist Circumference ◽  
Birth Cohort ◽  
Body Mass ◽  
Smoking Status ◽  
Later Life ◽  
Birth Cohort Study ◽  
Occupational Class ◽  
Cross Sectional

ObjectivesTo investigate whether cross-sectional and longitudinal associations of body mass index (BMI) and waist circumference (WC) with back pain change with age and extend into later life.DesignBritish birth cohort study.SettingEngland, Scotland and Wales.ParticipantsUp to 3426 men and women from the MRC National Survey of Health and Development.Primary outcome measuresBack pain (sciatica, lumbago or recurring/severe backache all or most of the time) was self-reported during nurse interviews at ages 36, 43, 53 and 60–64 years and in a postal questionnaire using a body manikin at age 68.ResultsFindings from mixed-effects logistic regression models indicated that higher BMI was consistently associated with increased odds of back pain across adulthood. Sex-adjusted ORs of back pain per 1 SD increase in BMI were: 1.13 (95% CI: 1.01 to 1.26), 1.11 (95% CI: 1.00 to 1.23), 1.17 (95% CI: 1.05 to 1.30), 1.31 (95% CI: 1.15 to 1.48) and 1.08 (95% CI: 0.95 to 1.24) at ages 36, 43, 53, 60–64 and 68–69, respectively. Similar patterns of associations were observed for WC. These associations were maintained when potential confounders, including education, occupational class, height, cigarette smoking status, physical activity and symptoms of anxiety and depression were accounted for. BMI showed stronger associations than WC in models including both measures.ConclusionsThese findings demonstrate that higher BMI is a persistent risk factor for back pain across adulthood. This highlights the potential lifelong consequences on back pain of the rising prevalence of obesity within the population.

scholarly journals The association between indoor temperature and body mass index in children: the PIAMA birth cohort study

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Floor R Scheffers ◽  
Marga BM Bekkers ◽  
Marjan Kerkhof ◽  
Ulrike Gehring ◽  
Gerard H Koppelman ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Birth Cohort ◽  
Body Mass ◽  
Birth Cohort Study ◽  
Indoor Temperature

scholarly journals Status gizi berhubungan positif dengan derajat nyeri sendi penderita osteoartritis lutut

2012 ◽  
Vol 8 (3) ◽  
pp. 144 ◽  
Author(s):  
Nyoman Kertia
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Knee Osteoarthritis ◽  
Body Mass ◽  
Joint Pain ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Knee Oa ◽  
Vas Score ◽  
Bivariate Correlation

Background: Knee osteoarthritis (OA) is a common disorder that is associated with significant morbidity, disability, and medical costs, particularly in its advanced stages. While the cause of knee OA remains unclear, it has been associated with various risk factors, such as age, sex, genetic predisposition, biomechanical, and obesity. Pain in osteoarthritis occurs due to combination of various factors. Pain significantly increases the medical and non medical cost in OA. Data showed that obesity will increase the mechanical stress and pain of knee OA. However, uncertainty remains regarding potential relationship between body mass index (BMI) and pain in osteoarthritis. Moreover, since obesity is one of modifiable and preventable risk factors for the onset and progression of the disease, it is important to know the correlation between BMI and severity of pain in knee OA.Objectives: To investigate the relationship between body mass index and severity of joint pain in knee osteoarthritis.Methods: A cross sectional study was conducted and subjects were osteoarthritis patients in rheumatology clinic of Sardjito general hospital. Body mass index and visual analogue scale (VAS) score were measured. Correlation between BMI and VAS score were analyzed by bivariate correlation test.Results: There were 80 patients with osteoarthritis who participated in the study. Mean BMI was 26.36 +4.23 kg/m2 and VAS score was 52.40+24.53 mm. The correlation test showed that there was a positive but non significant correlation between BMI and VAS scores (r = 0,11; p = 0,33).Conclusion: There was a positive but non significant correlation between body mass index and the severity of joint pain in knee osteoarthritis.

scholarly journals Longitudinal association of neighborhood variables with Body Mass Index in Dutch school-age children: The KOALA Birth Cohort Study

2015 ◽  
Vol 135 ◽  
pp. 99-108 ◽  
Author(s):  
Swantje C. Schmidt ◽  
Ester F.C. Sleddens ◽  
Sanne I. de Vries ◽  
Jessica Gubbels ◽  
Carel Thijs
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Birth Cohort ◽  
Body Mass ◽  
School Age Children ◽  
Birth Cohort Study ◽  
School Age ◽  
Longitudinal Association

scholarly journals Parental Body Mass Index and Behavioral Problems in Their Offspring: A Danish National Birth Cohort Study

2017 ◽  
Vol 186 (5) ◽  
pp. 593-602 ◽  
Author(s):  
Susanne Hvolgaard Mikkelsen ◽  
Lena Hohwü ◽  
Jørn Olsen ◽  
Bodil Hammer Bech ◽  
Zeyan Liew ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cohort Study ◽  
Birth Cohort ◽  
Body Mass ◽  
Behavioral Problems ◽  
Birth Cohort Study ◽  
Danish National Birth Cohort
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