scholarly journals Correlation of Quantitative Myasthenia Gravis and Myasthenia Gravis Activities of Daily Living scales in the MGTX study

2020 ◽  
Vol 62 (2) ◽  
pp. 261-266
Author(s):  
Tarrant McPherson ◽  
Inmaculada Aban ◽  
Petra W. Duda ◽  
Ramin Farzaneh‐Far ◽  
Gil I. Wolfe ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living

Reliability and Validity of Turkish Myasthenia Gravis-Activities of Daily Living Scale

2020 ◽  
pp. 153944922096107
Author(s):  
Ecem Karanfil ◽  
Yeliz Salcı ◽  
Ayla Fil-Balkan ◽  
Can Ebru Bekircan-Kurt ◽  
Sevim Erdem Özdamar ◽  
...  
Keyword(s):  
Construct Validity ◽  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Intraclass Correlation ◽  
Reliability And Validity ◽  
Life Questionnaire ◽  
Good Test ◽  
Retest Reliability ◽  
Test Retest Reliability

Linguistic, reliable, and valid secondary efficacy measures are important in clinical settings and studies. The aim of the study is to report test–retest reliability and construct validity of Turkish version of Myasthenia Gravis-Activities of Daily Living Scale (MG-ADL-T) in Myasthenia Gravis (MG) patients. Fifty-two ocular and generalized individuals with MG, applying to rehabilitation center, were included in the study. MG-ADL-T, MG quality-of-life questionnaire (MG-QoL), MG composite (MGC), quantitative MG score (QMGS), and pulmonary function test were administered. Reliability was assessed with intraclass correlation coefficient (ICC) and Cronbach’s alpha. Spearman correlation test and receiver operating characteristic (ROC) analysis were performed for construct validity. MG-ADL-T had fair internal consistency (Cronbach’s α = .67), excellent test–retest reliability (ICC = 0.96) and moderate construct validity (MG-QoL, r = 0.59; QMGS, r = .58; MGC, r = .68). MG-ADL, a unique scale that evaluates activities of daily living (ADL), has good test–retest reliability and construct validity in Turkish MG patients.

Physician- and self-assessed myasthenia gravis activities of daily living score

2017 ◽  
Vol 57 (3) ◽  
pp. 419-422
Author(s):  
Hye Lim Lee ◽  
Ju-Hong Min ◽  
Jin Myoung Seok ◽  
Eun Bin Cho ◽  
Hye Jin Cho ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living

Myasthenia gravis activities of daily living profile

Neurology ◽  
1999 ◽  
Vol 52 (7) ◽  
pp. 1487-1487 ◽  
Author(s):  
G. I. Wolfe ◽  
L. Herbelin ◽  
S. P. Nations ◽  
B. Foster ◽  
W. W. Bryan ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living

scholarly journals Cigarette Smoking and Activities of Daily Living in Ocular Myasthenia Gravis

2016 ◽  
Vol 36 (1) ◽  
pp. 37-40 ◽  
Author(s):  
Sean M. Gratton ◽  
Angela M. Herro ◽  
William J. Feuer ◽  
Byron L. Lam
Keyword(s):  
Cigarette Smoking ◽  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Ocular Myasthenia ◽  
Ocular Myasthenia Gravis

scholarly journals Advanced Comprehensive Rehabilitation Approach for Post-operative patient with Anterior Mediastinal Tumor: Atypical Case Report

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1112-1117
Author(s):  
Angela Kapoor ◽  
Vaishnavi Yadav ◽  
Pratik Phansopkar
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Neck Region ◽  
Early Mobilization ◽  
Early Recovery ◽  
Post Surgery ◽  
Supervised Exercise ◽  
Surgery Patient

Myasthenia gravis (MG) is an autoimmune disease in which muscle weakness and fatigability of the skeletal muscle are as a result of an antibody at the neuromuscular junction against the acetylcholine receptor (AChR) affecting ladies and older men. A thymoma occurs in approximately 15 per cent of adult diagnosed with Myasthenia gravis (MG). Thymectomy is used as a surgical approach which helps to reduce the symptoms. Structured comprehensive physiotherapy rehabilitation post-surgery helps to achieve a successful functional recovery. A 61 year old male patient was admitted with complain of lump in neck region, generalised weakness and early fatigability while doing Activities of daily living since 2 months. Investigations were done for the same which revealed thymoma and surgical intervention i.e. thymectomy was performed. Patient was referred to post opt rehabilitation with complains of incisional pain, cough with expectoration, early fatigue performing basic Activities of daily living and reduced strength. Following the surgery patient underwent physiotherapy which comprised of exercises, breathing retraining and early mobilization. The case report concludes that early excision of thymoma with prompt tailor made supervised exercise program helps in early recovery and achievement of functional goal.

scholarly journals PERBANDINGAN DOSIS PIRIDOSTIGMIN, PERFORMA FUNGSIONAL, DAN DERAJAT KLINIS PASIEN MIASTENIA GRAVIS SEBELUM DAN SETELAH TIMEKTOMI

2018 ◽  
Vol 35 (4) ◽  
Author(s):  
Christianty Sugiarto ◽  
Sobaryati Sobaryati ◽  
Henny Anggraini Sadeli ◽  
Tri Wahyu Murni
Keyword(s):  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Clinical Condition ◽  
Daily Living ◽  
Retrospective Cohort ◽  
Functional Performance ◽  
Clinical Symptoms ◽  
Analytic Study ◽  
Clinical Severity ◽  
Before And After

   COMPARISON BETWEEN PYRIDOSTIGMINE DOSE, FUNCTIONAL PERFORMANCE, AND CLINICAL SEVERITY IN MYASTHENIA GRAVIS PATIENTS BEFORE AND AFTER THYMECTOMYABSTRACTIntroduction: Myasthenia gravis (MG) is highly associated with thymic abnormalities. Most cases, show decreasing dosage of drugs and improving of clinical symptoms after thymectomy. However, in Indonesia, there are only limited number of studies have evaluated it.Aim: To evaluate and compare clinical condition of MG patients in Hasan Sadikin Hospital, Bandung before and after thymectomy.Methods: A retrospective cohort and descriptive analytic study on adult MG patients who had gone through thymectomy in Hasan Sadikin Hospital, Bandung from January 2014 to December 2016. Daily Pyridostigmine dosage comparison, functional performance using Myasthenia Gravis-Activities of Daily Living (MG-ADL) score, and clinical severity using Myasthenia Gravis Foundation of America (MGFA) classification before and six months after thymectomy were assessed.Results: There are 27 subjects, female:male 2.8:1, with a mean age of 36.44±14.46 years. Average daily Pyridostigmine dosage needed pre- and six months post-thymectomy were 240 (180–540)mg and 180 (0–480)mg respectively. The median of MG-ADL scores pre- and six months post-thymectomy were 10 (4–21) and 3 (0–18) respectively. The median of MGFA classification pre-and six months post-thymectomy were grade IVa (IIa–V) and IIb (normal–V) respectively.Discussion: There were significant decrease in daily Pyridostigmine dosage, improvements in functional performance, and improvements in clinical severity six months after thymectomy in MG patients.Keywords: MG-ADL, MGFA classification, pyridostigmine, thymectomy ABSTRAKPendahuluan: Penyakit miastenia gravis (MG) sering berhubungan dengan kelainan kelenjar timus. Pada kebanyakan kasus, timektomi dapat menurunkan kebutuhan dosis obat dan memperbaiki gejala klinis pasien MG. Di Indonesia penelitian mengenai hal ini masih sangat terbatas.Tujuan: Mengetahui perbandingan kondisi klinis pasien MG antara sebelum dan setelah dilakukan timektomi di RSUP Dr. Hasan Sadikin, Bandung.Metode: Penelitian kohort retrospektif, deskriptif analitik pada pasien MG dewasa yang telah dilakukan timektomi di RSUP Dr. Hasan Sadikin, Bandung, antara Januari 2014-Desember 2016. Dilakukan perbandingan dosis Piridostigmin per hari serta penilaian performa fungsional dengan skor Myasthenia Gravis-Activities of Daily Living (MG-ADL) dan derajat klinis berdasarkan klasifikasi Myasthenia Gravis Foundation of America (MGFA) antara sebelum dan 6 bulan setelah timektomi.Hasil: Diperoleh 27 subjek, perempuan:laki-laki 2,8:1, rerata usia 36,4±14,5 tahun. Rerata dosis Piridostigmin per hari sebelum timektomi 240 (rentang 180-540)mg dan 6 bulan setelah timektomi 180 (0-480)mg. Median skor MG-ADL sebelum timektomi adalah 10 (4-21) dan 6 bulan setelah timektomi 3 (0-18). Median klasifikasi MGFA sebelum timektomi adalah IVa (rentang IIa-V) sedangkan 6 bulan setelah timektomi adalah IIb (rentang normal-V).Diskusi: Terdapat penurunan dosis Piridostigmin, serta perbaikan performa fungsional dan derajat klinis yang bermakna antara sebelum dan 6 bulan setelah timektomi pada pasien MG.Kata kunci: Klasifikasi MGFA, MG-ADL, piridostigmin, timektomi

scholarly journals The analysis of quality of life using SF-36 among patients with myasthenia gravis in South Korea

2021 ◽  
Author(s):  
Juhyeon Kim ◽  
Jin Myoung Seok ◽  
Misong Choi ◽  
Byoung Joon Kim ◽  
Ansuk Jeong ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Myasthenia Gravis ◽  
Activities Of Daily Living ◽  
Daily Living ◽  
Short Form ◽  
Short Form Health Survey ◽  
Form Health ◽  
Sf 36 ◽  
Short Form Health

Abstract PurposePatients with Myasthenia gravis (MG) have poor health related quality of life (HRQoL), which negatively affects their activities of daily living. The purpose of this study was to analyze factors affecting HRQoL in patients with MG using the 36-Item Short-Form Health Survey (SF-36).MethodsWe prospectively studied patients with confirmed diagnosis of MG. Patients, who presented to the neuromuscular outpatient clinic, at a Samsung medical center in South Korea in a four-month period. Severity of MG was assessed by the Myasthenia Gravis Composite Scale (MGCS) and HRQoL was assessed by the 36-Item Short-Form Health Survey (SF-36) and activities of daily living was assessed by the Korean version of Myasthenia Gravis-specific Activities of Daily Living scale (K-MG-ADL).ResultsA total of 120 patients with MG were invited to participate in the study.We analyzed the difference of SF-36 score according to demographic and clinical characteristics in our MG patients. Significant differences were found according to sex, career change, marital status, MG type, and thymoma.ConclusionBy analyzing the specifics of the HRQoL, the current study demonstrated that this should be reflected in the treatment guidelines for MG patients.

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