Controlled assembly of gold and albumin nanoparticles to form hybrid multimeric nanomaterials

2021 ◽  
Author(s):  
Akhilan Elangovan ◽  
Dhananjay Suresh ◽  
Andrew O. Tarim ◽  
Anandhi Upendran ◽  
Raghuraman Kannan
Keyword(s):  
Controlled Assembly ◽  
Albumin Nanoparticles

scholarly journals Microparticles with hetero-nanointerfaces: controlled assembly of cobalt hydroxide and nickel hydroxide nanoclusters towards improved electrochemical functions

2019 ◽  
Vol 7 (44) ◽  
pp. 25290-25296 ◽  
Author(s):  
Naoki Tarutani ◽  
Yasuaki Tokudome ◽  
Matías Jobbágy ◽  
Galo J. A. A. Soler-Illia ◽  
Masahide Takahashi
Keyword(s):  
Nickel Hydroxide ◽  
Metal Hydroxide ◽  
Cobalt Hydroxide ◽  
Controlled Assembly

Hybridization of electrochemical functions derived from large hetero-interfaces by assembly of layered metal hydroxide nanoclusters.

scholarly journals Building a stem cell-based primate uterus

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Sophie Bergmann ◽  
Magdalena Schindler ◽  
Clara Munger ◽  
Christopher A. Penfold ◽  
Thorsten E. Boroviak
Keyword(s):  
Stem Cell ◽  
Fetal Development ◽  
Embryo Implantation ◽  
In Vitro Models ◽  
Uterine Tissue ◽  
Controlled Assembly ◽  
Uterine Cancers ◽  
Term Births ◽  
Key Questions

AbstractThe uterus is the organ for embryo implantation and fetal development. Most current models of the uterus are centred around capturing its function during later stages of pregnancy to increase the survival in pre-term births. However, in vitro models focusing on the uterine tissue itself would allow modelling of pathologies including endometriosis and uterine cancers, and open new avenues to investigate embryo implantation and human development. Motivated by these key questions, we discuss how stem cell-based uteri may be engineered from constituent cell parts, either as advanced self-organising cultures, or by controlled assembly through microfluidic and print-based technologies.

scholarly journals The Development of the Innovative Synthesis Methodology of Albumin Nanoparticles Supported by Their Physicochemical, Cytotoxic and Hemolytic Evaluation

Materials ◽  
2021 ◽  
Vol 14 (16) ◽  
pp. 4386
Author(s):  
Sonia Kudłacik-Kramarczyk ◽  
Anna Drabczyk ◽  
Magdalena Głąb ◽  
Paweł Gajda ◽  
Anna Czopek ◽  
...  
Keyword(s):  
Spherical Shape ◽  
Dermal Fibroblasts ◽  
Albumin Concentration ◽  
Salting Out ◽  
Tem Analysis ◽  
Albumin Nanoparticles ◽  
Vis Spectroscopy ◽  
Physicochemical Evaluation ◽  
Normal Human ◽  
Synthesis Methodology

Many studies are being performed to develop effective carriers for controlled cytostatic delivery wherein albumin is a promising material due to its tendency to accumulate near cancer cells. The novelty of this work involves the development of the synthesis methodology of albumin nanoparticles and their biological and physicochemical evaluation. Albumin particles were obtained via the salt-induced precipitation and K3PO4 was used as a salting-out agent. Various concentrations of protein and salting-out agent solutions were mixed using a burette or a syringe system. It was proved that the size of the particles depended on the concentrations of the reagents and the methodology applied. As a result of a process performed using a burette and 2 M K3PO4, albumin spheres having a size 5–25 nm were obtained. The size of nanospheres and their spherical shape was confirmed via TEM analysis. The use of a syringe system led to preparation of particles of large polydispersity. The highest albumin concentration allowing for synthesis of homogeneous particles was 2 g/L. The presence of albumin in spheres was confirmed via the FT-IR technique and UV-Vis spectroscopy. All samples showed no cytotoxicity towards normal human dermal fibroblasts and no hemolytic properties against human erythrocytes (the hemolysis did not exceed 2.5%).

Gold nanocluster-loaded hybrid albumin nanoparticles with fluorescence-based optical visualization and photothermal conversion for tumor detection/ablation

2019 ◽  
Vol 304 ◽  
pp. 7-18 ◽  
Author(s):  
Sanghyun Park ◽  
Hanju Kim ◽  
Su Chan Lim ◽  
Kyungseop Lim ◽  
Eun Seong Lee ◽  
...  
Keyword(s):  
Tumor Detection ◽  
Gold Nanocluster ◽  
Photothermal Conversion ◽  
Albumin Nanoparticles ◽  
Optical Visualization

Shape-Controlled Assembly of Nanowires for Photonic Elements

ACS Photonics ◽  
2016 ◽  
Vol 3 (12) ◽  
pp. 2285-2290 ◽  
Author(s):  
You-Shin No ◽  
Lin Xu ◽  
Max N. Mankin ◽  
Hong-Gyu Park
Keyword(s):  
Controlled Assembly ◽  
Shape Controlled

scholarly journals Polo-like kinase is required for Golgi and bilobe biogenesis in Trypanosoma brucei

2008 ◽  
Vol 181 (3) ◽  
pp. 431-438 ◽  
Author(s):  
Christopher L. de Graffenried ◽  
Helen H. Ho ◽  
Graham Warren
Keyword(s):  
Cell Cycle ◽  
Endoplasmic Reticulum ◽  
Trypanosoma Brucei ◽  
Protozoan Parasite ◽  
Controlled Assembly

A bilobed structure marked by TbCentrin2 regulates Golgi duplication in the protozoan parasite Trypanosoma brucei. This structure must itself duplicate during the cell cycle for Golgi inheritance to proceed normally. We show here that duplication of the bilobed structure is dependent on the single polo-like kinase (PLK) homologue in T. brucei (TbPLK). Depletion of TbPLK leads to malformed bilobed structures, which is consistent with an inhibition of duplication and an increase in the number of dispersed Golgi structures with associated endoplasmic reticulum exit sites. These data suggest that the bilobe may act as a scaffold for the controlled assembly of the duplicating Golgi.

Ganciclovir-loaded albumin nanoparticles: characterization and in vitro release properties

2001 ◽  
Vol 12 (3) ◽  
pp. 251-259 ◽  
Author(s):  
Marta Merodio ◽  
Amaia Arnedo ◽  
M.Jesús Renedo ◽  
Juan M Irache
Keyword(s):  
In Vitro Release ◽  
Albumin Nanoparticles ◽  
Nanoparticles Characterization ◽  
Vitro Release

Human serum albumin nanoparticles modified with apolipoprotein A-I cross the blood-brain barrier and enter the rodent brain

2010 ◽  
Vol 18 (10) ◽  
pp. 842-848 ◽  
Author(s):  
Anja Zensi ◽  
David Begley ◽  
Charles Pontikis ◽  
Celine Legros ◽  
Larisa Mihoreanu ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Albumin Nanoparticles ◽  
Apolipoprotein A ◽  
Rodent Brain ◽  
Blood Brain
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