Risk factors for suicide mortality and cancer‐specific mortality among patients with gastric adenocarcinoma: A SEER based study

2021 ◽  
Author(s):  
Alaa Ahmed Elshanbary ◽  
Mohamed Sayed Zaazouee ◽  
Sara Mohamed Hasan ◽  
Walid Abdel‐Aziz
Keyword(s):  
Risk Factors ◽  
Gastric Adenocarcinoma ◽  
Suicide Mortality ◽  
Specific Mortality ◽  
Cancer Specific Mortality ◽  
Risk Factors For Suicide

scholarly journals Mortality Risk factors and SOX2 and mTOR expression in Patients with Esophageal Cancer

2022 ◽  
Vol 67 (4) ◽  
pp. 346-357
Author(s):  
Gao Yu ◽  
Yang Yuexin ◽  
Lv Yin ◽  
Zhang Yiyin ◽  
Kang Mei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Esophageal Cancer ◽  
Cardiovascular Mortality ◽  
Clinical Stage ◽  
Specific Protein ◽  
Expression Levels ◽  
Specific Mortality ◽  
Before And After ◽  
Cancer Specific Mortality ◽  
Distant Spread

Causes of mortality in EC patients are not confined to cancer-specific mortality but include various protein expressions of SOX2 and mTOR in Esophageal Cancer patients and their correlation with the clinical stage. Data about the risk factors and involvement of cancer-specific protein are still lacking. This study aimed to define the risk factors and association of SOX2 and mTOR expression in mortality in patients with EC. We conducted a retrospective cohort study to assess the risk factors for cancer-specific mortality and cardiovascular mortality in patients with esophageal cancer (EC). The expression rates of SOX2, as well as MTO, were checked in patients. The multivariate analysis revealed a high-risk EC mortality with age ≥ 65 years, black race, grade, stage, and sequence of treatment; radiation after surgery; radiation before and after surgery; Surgery both before and after radiation. While the cardiovascular mortality increased with age ≥ 65 years, adenocarcinoma type, grade, stage, and sequence of treatment. The expression rates of SOX2, as well as mTOR, were 75.5 percent and 86.8 percent in Esophageal Cancer, while were 10.7 percent and 7.5 percent in osteochondroma, respectively, which was statistically significant (P<0.05). Risk factors for cancer-specific mortality and cardiovascular mortality in EC patients include older age at diagnosis, male sex, non-married status, grade III of the tumor, the regional or distant spread of the tumor, no cancer-directed therapy. The expression levels of SOX2, mTOR, and the total survival time were related to the different stages. It shows an upward trend for the expression levels of mTOR and SOX2 in Esophageal Cancer tissues. The expression levels of SOX2 and mTOR are related to the clinical stage, metastasis, and prognosis.

Long-term risk factors for suicide mortality after attempted suicide - Findings of a 14-year follow-up study

2001 ◽  
Vol 104 (2) ◽  
pp. 117-121 ◽  
Author(s):  
Jaana Suokas ◽  
Kirsi Suominen ◽  
Erkki Isometsä ◽  
Aini Ostamo ◽  
Jouko Lönnqvist
Keyword(s):  
Risk Factors ◽  
Attempted Suicide ◽  
Suicide Mortality ◽  
Follow Up Study ◽  
Risk Factors For Suicide

Excessive suicide mortality and risk factors for suicide among patients with heroin dependence

2014 ◽  
Vol 145 ◽  
pp. 224-230 ◽  
Author(s):  
Chun-Hung Pan ◽  
Jia-Rong Jhong ◽  
Shang-Ying Tsai ◽  
Shih-Ku Lin ◽  
Chiao-Chicy Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heroin Dependence ◽  
Suicide Mortality ◽  
Risk Factors For Suicide

scholarly journals Risk Factors for Lymph Node Metastasis of Soft Tissue Sarcomas of the Head, Neck and Extremities, And the Clinical Significance of Negative Lymph Node Dissection

2021 ◽  
Author(s):  
Qikun Liu ◽  
Xiaojun Yu ◽  
Mengwei Li ◽  
Zhiwei Li ◽  
Yongqiao Jiang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lymph Node ◽  
Soft Tissue Sarcomas ◽  
Node Dissection ◽  
Cancer Specific Survival ◽  
Node Metastasis ◽  
Specific Mortality ◽  
Size Grade ◽  
Cancer Specific Mortality ◽  
Head Neck

Abstract Background: To determine the risk factors for lymph node metastasis (LNM) of soft tissue sarcomas (STS) of the head, neck, and extremities, and the clinical outcome of negative lymph node dissection (NLND). Methods: We pooled patients of STS using the Surveillance, Epidemiology, and End Results (SEER) database from 1988 to 2015. Logistics regression analysis to identify risk factors for LNM, the Cox proportional hazards model and Fine-Grey’s model were used for survival analysis, Propensity score matching analysis (PSM) was further used to clarify the impact of NLND on patient prognosis.Results: A total of 3,276 patients were enrolled in our study, of whom 283 (8.6%) developed LNM. Rhabdomyosarcoma had the highest rate of LNM (25.3%), followed by clear cell sarcoma (16.8%) and epithelioid sarcoma (12.4%), while leiomyosarcoma had the lowest rate of LNM (1.3%). Sex, tumor size, grade, histology, and site were significantly associated with LNM. Age, tumor size, grade, stage, histology, and marital status were independent prognostic factors for the cancer-specific survival for patients without LNM. For specific histologic subtypes of STS, NLND significantly improves overall survival (HR: 0.718, 95%CI, 0.535-0.962; P=0.026) and cancer-specific survival (HR: 0.699, 95%CI, 0.506-0.967; P=0.031) and reduces cancer-specific mortality (Gray’s test, P=0.017). However, for patients with leiomyosarcoma, NLND did not improve overall survival (P=0.46) or reduce cancer-specific mortality (Gray’s test, P=0.772).Conclusions: We identified the rate of LNM and risk factors for LNM in STS of the head, neck and extremities. In addition, prophylactic NLND treatment is necessary and has a clinical benefit for patients with STS who are at high risk for LNM, but has no significant impact on the prognosis of patients with leiomyosarcoma.

scholarly journals Incidence of and sociological risk factors for suicide death in patients with leukemia: A population-based study

2020 ◽  
Vol 48 (5) ◽  
pp. 030006052092246
Author(s):  
Jin Yang ◽  
Qingqing Liu ◽  
Fanfan Zhao ◽  
Xiaojie Feng ◽  
Rahel Elishilia Kaaya ◽  
...  
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Population Based ◽  
Suicide Mortality ◽  
Seer Database ◽  
Suicide Death ◽  
Logistic Regression Models ◽  
Sociological Factors ◽  
Risk Of Death ◽  
Risk Factors For Suicide

Objectives Suicide is closely related to sociological factors, but sociological analyses of suicide risk in leukemia are lacking. This study is the first to use the Surveillance, Epidemiology, and End Results Program (SEER) database to analyze sociological risk factors for suicide death in leukemia patients. Methods A retrospective search of the SEER database was conducted. Logistic regression was used to identify independent risk factors for suicide death. Variables significant in the univariate logistic regression models were subsequently analyzed using multivariate regression. Results The death rate was highest in California (1.73%). Suicide mortality was more common during the 1970s and 1980s, after which it trended downward. Young age at diagnosis (18–34 vs. >64 years: odds ratio [OR] = 1.537, 95% confidence interval [CI] = 1.007–2.347; 35–64 vs. >64 years: OR = 1.610, 95% CI = 1.309–1.979), being male (OR = 1.518, 95% CI = 1.230–1.873), and living where a high proportion of people have at least a bachelor’s degree (>50% vs. <20%: OR = 8.115, 95% CI = 5.053–13.034) significantly increased suicide death risk. Conclusion Our findings could increase clinician awareness of and appropriate support for leukemia patients at risk of death by suicide.

scholarly journals Suicide Mortality in the Americas – Regional Report 2015-2019

2021 ◽  
Keyword(s):  
Risk Factors ◽  
Mortality Rates ◽  
Suicide Mortality ◽  
Fourth Edition ◽  
Country Level ◽  
Specific Risk ◽  
Trends Over Time ◽  
Gender Specific ◽  
Over Time ◽  
Risk Factors For Suicide

This report provides updated data on suicide in the Region of the Americas and is issued every five years, this being the fourth edition. In addition to including analysis similar to previous reports (suicide according to age, sex, as well as methods used), this report includes an expanded set of analysis on risk factors for suicide in the Americas: the analysis of the annual age-standardized gender-specific suicide morality rate trends over time by country and sub-region and to identify points of inflection, and evaluates the association of specific risk factors on country-level suicide mortality rates.

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