scholarly journals Differential impact of paired patient‐derived BPH and normal adjacent stromal cells on benign prostatic epithelial cell growth in 3D culture

The Prostate ◽  
2020 ◽  
Vol 80 (14) ◽  
pp. 1177-1187
Author(s):  
Wei Chen ◽  
Laura E. Pascal ◽  
Ke Wang ◽  
Rajiv Dhir ◽  
Alexa M. Sims ◽  
...  
2001 ◽  
Vol 16 (5) ◽  
pp. 836-845 ◽  
Author(s):  
Julia T. Arnold ◽  
David G. Kaufman ◽  
Markku Seppälä ◽  
Bruce A. Lessey

The Prostate ◽  
1995 ◽  
Vol 26 (3) ◽  
pp. 123-132 ◽  
Author(s):  
Anko Kooistra ◽  
Josée J. König ◽  
Diederick M. Keizer ◽  
Johan C. Romijn ◽  
Fritz H. Schröder

2002 ◽  
Vol 132 (10) ◽  
pp. 3191-3194 ◽  
Author(s):  
Anuradha Rao ◽  
Ralph D. Woodruff ◽  
Wendy N. Wade ◽  
Timothy E. Kute ◽  
Scott D. Cramer

Author(s):  
V. F. Allison ◽  
G. C. Fink ◽  
G. W. Cearley

It is well known that epithelial hyperplasia (benign hypertrophy) is common in the aging prostate of dogs and man. In contrast, little evidence is available for abnormal epithelial cell growth in seminal vesicles of aging animals. Recently, enlarged seminal vesicles were reported in senescent mice, however, that enlargement resulted from increased storage of secretion in the lumen and occurred concomitant to epithelial hypoplasia in that species.The present study is concerned with electron microscopic observations of changes occurring in the pseudostratified epithelium of the seminal vescles of aging rats. Special attention is given to certain non-epithelial cells which have entered the epithelial layer.


1996 ◽  
Vol 63 (1_suppl) ◽  
pp. 65-68
Author(s):  
S. De Angeli ◽  
A. Fandella ◽  
C. Gatto ◽  
S. Buoro ◽  
C. Favretti ◽  
...  

A study was carried out on the effect of stroma-epithelium interaction on cellular growth and morphology in co-coltures of U285 prostatic epithelial cells with human prostatic and esophageal stromal cells and with murine fibroblasts of the 3T3-J2 line. The proliferation rate was determined by growth tests of neutral red and kenacid blue. Morphological observations were made under optical microscope on the same cultures used for the growth tests. Results highlighted a marked reduction in cellular growth in the co-cultures compared to control cultures, as well as the tendency of the stromal and epithelial cells to re-organise themselves in pseudo-acinous structures.


2002 ◽  
Vol 31 (1-3) ◽  
pp. 79-88 ◽  
Author(s):  
Longchuan Bai ◽  
Craig Logsdon ◽  
Juanita L. Merchant

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