OC14.03: Added value of fetal MR tractography in evaluation of the short corpus callosum: preliminary results

Monazite is one of the most valuable natural resources for rare earth oxides (REOs) used as dopants with high added value in ceramic materials for extreme environments applications. The complexity of the separation process in individual REOs, due to their similar electronic configuration and physical–chemical properties, is reflected in products with high price and high environmental footprint. During last years, there was an increasing interest for using different mixtures of REOs as dopants for high temperature ceramics, in particular for ZrO2-based thermal barrier coatings (TBCs) used in aeronautics and energy co-generation. The use of mixed REOs may increase the working temperature of the TBCs due to the formation of tetragonal and cubic solid solutions with higher melting temperatures, avoiding grain size coarsening due to interface segregation, enhancing its ionic conductivity and sinterability. The thermal stability of the coatings may be further improved by using rare earth zirconates with perovskite or pyrochlore structures having no phase transitions before melting. Within this research framework, firstly we present a review analysis about results reported in the literature so far about the use of ZrO2 ceramics doped with mixed REOs for high temperature applications. Then, preliminary results about TBCs fabricated by electron beam evaporation starting from mixed REOs simulating the real composition as occurring in monazite source minerals are reported. This novel recipe for ZrO2-based TBCs, if optimized, may lead to better materials with lower costs and lower environmental impact, as a result of the elimination of REOs extraction and separation in individual lanthanides. Preliminary results on the compositional, microstructure, morphological, and thermal properties of the tested materials are reported.

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Computer-Assisted Classification Patterns in Autoimmune Diagnostics: The AIDA Project

BioMed Research International ◽

10.1155/2016/2073076 ◽

2016 ◽

Vol 2016 ◽

pp. 1-9 ◽

Cited By ~ 17

Author(s):

Amel Benammar Elgaaied ◽

Donato Cascio ◽

Salvatore Bruno ◽

Maria Cristina Ciaccio ◽

Marco Cipolla ◽

...

Keyword(s):

Fluorescence Intensity ◽

Gold Standard ◽

Added Value ◽

Computer Assisted ◽

Computer Aided Detection ◽

Preliminary Results ◽

Cad System ◽

Cross Border ◽

Cross Border Cooperation ◽

Better Than

Antinuclear antibodies (ANAs) are significant biomarkers in the diagnosis of autoimmune diseases in humans, done by mean of Indirect ImmunoFluorescence (IIF) method, and performed by analyzing patterns and fluorescence intensity. This paper introduces the AIDA Project (autoimmunity: diagnosis assisted by computer) developed in the framework of an Italy-Tunisia cross-border cooperation and its preliminary results. A database of interpreted IIF images is being collected through the exchange of images and double reporting and a Gold Standard database, containing around 1000 double reported images, has been settled. The Gold Standard database is used for optimization of a CAD (Computer Aided Detection) solution and for the assessment of its added value, in order to be applied along with an Immunologist as a second Reader in detection of autoantibodies. This CAD system is able to identify on IIF images the fluorescence intensity and the fluorescence pattern. Preliminary results show that CAD, used as second Reader, appeared to perform better than Junior Immunologists and hence may significantly improve their efficacy; compared with two Junior Immunologists, the CAD system showed higher Intensity Accuracy (85,5% versus 66,0% and 66,0%), higher Patterns Accuracy (79,3% versus 48,0% and 66,2%), and higher Mean Class Accuracy (79,4% versus 56,7% and 64.2%).

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Added value of SPECT/CT in patients suspected of having bone infection: preliminary results

Archives of Orthopaedic and Trauma Surgery ◽

10.1007/s00402-006-0259-6 ◽

2006 ◽

Vol 127 (3) ◽

pp. 211-221 ◽

Cited By ~ 76

Author(s):

Marius Horger ◽

Susanne Martina Eschmann ◽

Christina Pfannenberg ◽

Dieter Storek ◽

Reinhard Vonthein ◽

...

Keyword(s):

Bone Infection ◽

Added Value ◽

Preliminary Results

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Does fetal MR alter the management of pregnancy in the diagnosis of isolated corpus callosum agenesis?

Perinatal Journal ◽

10.2399/prn.20.0282015 ◽

2020 ◽

Vol 28 (2) ◽

pp. 113-119

Author(s):

Mustafa Behram ◽

Salim Sezer ◽

Yasemin Doğan ◽

Züat Acar ◽

Zeynep Gedik Özköse ◽

...

Keyword(s):

Corpus Callosum ◽

Mr Imaging ◽

Statistical Difference ◽

Cultural Factors ◽

Corpus Callosum Agenesis ◽

The Family ◽

The Impact ◽

Fetal Mr ◽

Family Decisions

Objective To determine if fetal MR alters the management of pregnancy and family decisions in the isolated corpus callosum agenesis (CCA) cases or not. Methods Fetal MR was carried out in the cases diagnosed with CCA in the Perinatology Unit of our hospital between 2013 and 2019 after they were differentiated as complex and isolated CCA cases. The impact of MR results on the family decisions and their approaches towards termination were assessed. Results A total of 109 out 139 cases were evaluated as isolated CCA. While 93 (85.32%) of them were diagnosed with the complete CCA, 16 (14.68%) cases were diagnosed with the partial CCA. When the period after 2017 during which fetal MR was recommended to all patients was reviewed, it was seen that 7 (23.3%) of 30 cases who underwent fetal MR and 2 (20%) of 10 cases who did not undergo fetal MR terminated their pregnancies. There was no statistical difference between two groups in terms of the decisions of the patients for gestational termination who did and did not undergo fetal MR. Conclusion Fetal MR imaging in the isolated CCA does not change the decisions of the families for the gestational termination. In terms of the termination decision, week of gestation and socio-cultural factors may have more impacts.

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Added value of pre-biopsy prostate multiparametric MRI in biopsy-naïve patients: Preliminary results of the MRI-FIRST trial

European Urology Supplements ◽

10.1016/s1569-9056(17)30558-4 ◽

2017 ◽

Vol 16 (3) ◽

pp. e863-e864 ◽

Cited By ~ 2

Author(s):

O. Rouviere ◽

P. Puech ◽

R. Renard Penna ◽

M. Claudon ◽

C. Roy ◽

...

Keyword(s):

Multiparametric Mri ◽

Added Value ◽

Preliminary Results

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Added Value of Fetal MRI in the Evaluation of Fetal Anomalies of the Corpus Callosum: A Retrospective Analysis of 78 Cases

Ultraschall in der Medizin - European Journal of Ultrasound ◽

10.1055/a-0838-9055 ◽

2018 ◽

Vol 39 (05) ◽

pp. 513-525

Author(s):

Mirra Manevich-Mazor ◽

Alina Weissmann-Brenner ◽

Omer Bar Yosef ◽

Chen Hoffmann ◽

Roei Mazor ◽

...

Keyword(s):

Corpus Callosum ◽

Retrospective Analysis ◽

Fetal Mri ◽

Added Value ◽

Fetal Anomalies

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Corpus callosum agenesis: Role of fetal MR: A case report and review of the literature

Journal of the Neurological Sciences ◽

10.1016/j.jns.2021.118326 ◽

2021 ◽

Vol 429 ◽

pp. 118326

Author(s):

Radhouane Achour ◽

Dhekra Trabelsi ◽

Rim Ben Hmid

Keyword(s):

Case Report ◽

Corpus Callosum ◽

Review Of The Literature ◽

Corpus Callosum Agenesis ◽

Fetal Mr

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Added Value of Fetal MRI in the Evaluation of Fetal Anomalies of the Corpus Callosum: A Retrospective Analysis of 78 Cases

Ultraschall in der Medizin - European Journal of Ultrasound ◽

10.1055/s-0043-113820 ◽

2018 ◽

Vol 39 (05) ◽

pp. 513-525 ◽

Cited By ~ 1

Author(s):

Mirra Manevich-Mazor ◽

Alina Weissmann-Brenner ◽

Omer Bar Yosef ◽

Chen Hoffmann ◽

Roei Mazor ◽

...

Keyword(s):

Decision Making ◽

Corpus Callosum ◽

Clinical Decision Making ◽

Brain Mri ◽

Fetal Brain ◽

Fetal Mri ◽

Clinical Decision ◽

Added Value ◽

Callosal Agenesis

Abstract Objective To evaluate the added value of fetal MRI to ultrasound in detecting and specifying callosal anomalies, and its impact on clinical decision making. Methods Fetuses with a sonographic diagnosis of an anomalous corpus callosum (CC) who underwent a subsequent fetal brain MRI between 2010 and 2015 were retrospectively evaluated and classified according to the severity of the findings. The findings detected on ultrasound were compared to those detected on MRI. An analysis was performed to assess whether fetal MRI altered the group classification, and thus the management of these pregnancies. Results 78 women were recruited following sonographic diagnoses of either complete or partial callosal agenesis, short, thin or thick CC. Normal MRI studies were obtained inµ19 cases (24 %). Among these, all children available for follow-up received an adequate adaptive score in their Vineland II adaptive behavior scale assessment. Analysis of the concordance between US and MRI demonstrated a substantial level of agreement for complete callosal agenesis (kappa: 0.742), moderate agreement for thin CC (kappa: 0.418) and fair agreement for all other callosal anomalies. Comparison between US and MRI-based mild/severe findings classifications revealed that MRI contributed to a change in the management for 28 fetuses (35.9 %), mostly (25 fetuses, 32.1 %) in favor of pregnancy preservation. Conclusion Fetal MRI effectively detects callosal anomalies and enables satisfactory validation of the presence or absence of callosal anomalies identified by ultrasound and adds valuable data that improves clinical decision making.

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