scholarly journals Selenium nanoparticles are more efficient than sodium selenite in reducing the toxicity of aflatoxin B 1 in Japanese quail

2021 ◽  
Author(s):  
Seyed Kaveh Khazraei ◽  
Sayed Ali Tabeidian ◽  
Mahmood Habibian
Keyword(s):  
Japanese Quail ◽  
Sodium Selenite ◽  
Selenium Nanoparticles ◽  
Aflatoxin B

Protective effects of sodium selenite and selenium nanoparticles against experimental colon carcinogenesis in mice

2016 ◽  
Vol 40 (3) ◽  
pp. 101-108 ◽  
Author(s):  
Do-Youn Jang ◽  
◽  
Sung-June Kim ◽  
Jae-Hwang Jeong ◽  
Sang Yoon Nam ◽  
...  
Keyword(s):  
Sodium Selenite ◽  
Colon Carcinogenesis ◽  
Selenium Nanoparticles ◽  
Protective Effects

scholarly journals Radiolytic Synthesis and Characterization of Selenium Nanoparticles: Comparative Biosafety Evaluation with Selenite and Ionizing Radiation

2021 ◽  
Author(s):  
Alline Gomes Pereira ◽  
Luanai Graziele Luquini Gerolis ◽  
Letícia Satler Gonçalves ◽  
Luciana Mara Costa Moreira ◽  
Pedro Lana Gastelois ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Sodium Selenite ◽  
Structural Parameters ◽  
Reactive Oxygen Species Generation ◽  
Protein Carbonylation ◽  
Selenium Nanoparticles ◽  
Spherical Particles ◽  
Water Radiolysis

Abstract Selenium nanoparticles (SeNPs) were synthesized by irradiating a solution containing sodium selenite (Se+4) as the precursor in YPG liquid medium with gamma-rays. Spherical particles were formed after reactions of sodium selenite with hydrated electrons (eaq-) and hydrogen radicals (H•) produced following water radiolysis. No hazardous reducing agents were employed. The obtained nanoparticles were morphologically characterized, and their physicochemical and structural parameters were analyzed. SeNPs characterization showed all selenium in the Se0 state. We incubated Saccharomyces cerevisiae cells with the SeNPs for 24 h and then challenged the cells with ionizing radiation. After radiation exposure, cells were assessed for cell viability, lipid peroxidation, protein carbonylation, free radical generation, and total sulfhydryl content. The synthesized SeNPs were considered safe and less toxic at the concentration employed than the same selenite concentration. Except for the protein carbonylation results, there were no other significant modifications in viability or the oxidative stress parameters in SeNP-treated cells. It was concluded that 1 mM of the synthesized SeNPs does not trigger oxidative stress. Furthermore, we verified that SeNPs attenuate the reactive oxygen species generation after in vitro ionizing radiation exposure. These observations open up tremendous possibilities for radiosensitizer development.

scholarly journals The Effects of Oral Consumption of Selenium Nanoparticles on Chemotactic and Respiratory Burst Activities of Neutrophils in Comparison with Sodium Selenite in Sheep

2011 ◽  
Vol 146 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Gholam Ali Kojouri ◽  
Sirous Sadeghian ◽  
Abdonnaser Mohebbi ◽  
Mohammad Reza Mokhber Dezfouli
Keyword(s):  
Respiratory Burst ◽  
Sodium Selenite ◽  
Selenium Nanoparticles ◽  
Oral Consumption

Sodium selenite/selenium nanoparticles (SeNPs) protect cardiomyoblasts and zebrafish embryos against ethanol induced oxidative stress

2015 ◽  
Vol 32 ◽  
pp. 135-144 ◽  
Author(s):  
Kalimuthu Kalishwaralal ◽  
Subhaschandrabose Jeyabharathi ◽  
Krishnan Sundar ◽  
Azhaguchamy Muthukumaran
Keyword(s):  
Oxidative Stress ◽  
Sodium Selenite ◽  
Selenium Nanoparticles ◽  
Zebrafish Embryos

scholarly journals Differential protein expression of Caco-2 cells treated with selenium nanoparticles compared with sodium selenite and selenomethionine

2014 ◽  
Vol 9 (1) ◽  
pp. 589 ◽  
Author(s):  
Linglin Fu ◽  
Xuxia Yan ◽  
Xinming Ruan ◽  
Junda Lin ◽  
Yanbo Wang
Keyword(s):  
Protein Expression ◽  
Sodium Selenite ◽  
Selenium Nanoparticles ◽  
Differential Protein Expression ◽  
Differential Protein

scholarly journals simple method for preparing elemental selenium nano- coating inside a silicone surface

2021 ◽  
pp. 35-43
Author(s):  
Khandsuren Badgar ◽  
József Prokisch
Keyword(s):  
Ascorbic Acid ◽  
Sodium Selenite ◽  
Selenium Supplementation ◽  
Selenium Nanoparticles ◽  
Farm Animals ◽  
Silicone Tube ◽  
Simple Method ◽  
X Ray ◽  
Nano Coating ◽  
Silicone Surface

Selenium nanoparticles (SeNPs) with a bright red colour have aroused worldwide attention due to their unique properties in selenium supplementation because of their low toxicity and favourable bioavailability. A simple method was developed for making a red selenium nanolayer on the inner surface of Polyvinyl chloride (PVC) and silicone tube. The selenium nanoparticles were produced by the reaction of sodium selenite and ascorbic acid. Red amorphous selenium nanoparticles have been successfully synthesized by the reaction of 500 mg dm-3 Se (sodium selenite) solution with 10 g dm-3 ascorbic acid solution at room temperature, and morphology was confirmed by X-ray diffraction analysis (XRD). The coating density was compared on PVC and silicone surfaces by using Scanning Electron Microscopy (SEM) and Energy-dispersive X-ray (EDS) analysis. The nanolayer with about 16 µm thickness on the silicone surface significantly evenly distributed compared to the PVC surface. The selenium coated silicone tube could be a good source of selenium for a continuous, low-level selenium supplementation of farm animals via drinking water.

The Relative in vitro Sensitivity to Aflatoxin B 1 of Tracheal Organ Cultures Prepared from Day-Old Chickens, Ducks, Japanese Quail, and Turkeys

1973 ◽  
Vol 17 (1) ◽  
pp. 166 ◽  
Author(s):  
W. M. Colwell ◽  
R. C. Ashley ◽  
D. G. Simmons ◽  
P. B. Hamilton
Keyword(s):  
Japanese Quail ◽  
Organ Cultures ◽  
In Vitro Sensitivity ◽  
Aflatoxin B

scholarly journals Antioxidant status of rats’ blood and liver affected by sodium selenite and selenium nanoparticles

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4862 ◽  
Author(s):  
Lenka Urbankova ◽  
Pavel Horky ◽  
Jiri Skladanka ◽  
Magdalena Pribilova ◽  
Vendula Smolikova ◽  
...  
Keyword(s):  
Antioxidant Status ◽  
Sodium Selenite ◽  
Model Organism ◽  
Essential Element ◽  
Selenium Nanoparticles ◽  
Control Group ◽  
Positive Effects ◽  
Rat Strain ◽  
Higher Doses ◽  
Total Selenium

Background Selenium is an essential element; however, at higher doses, it can be toxic. Therefore, alternative nanotechnological solutions are required to overcome toxicological issues, rather than conventional alternatives. Nanoparticles show new and promising properties that may be able to suppress toxicity while maintaining the positive effects of selenium on an organism. The aim of the experiment was to determine the influence of sodium selenite and selenium nanoparticles (SeNPs) on the antioxidant status of rats. Methods The males of the outbreed rat strain Wistar albino were selected as a model organism. Animals were fed different forms of selenium. The control group was given a mixture without selenium addition, whereas other groups were fed a mixture containing sodium selenite, Se-49, and Se-100 SeNPs respectively. The duration of the trial was 30 days. Results Analysis of blood and liver was performed where the concentration of reduced (GSH) and oxidised (GSSG) glutathione, and total selenium content were measured. In the liver, a significant reduction in GSSG was found for all experiment groups. Blood samples showed a significant reduction in GSH and an increase in GSSG. Discussion These results show that SeNPs may be an alternative to dietary selenium for animal organisms.

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