Glucocorticoid-Mediated Suppression of the Promoter Activity of the Cyclooxygenase-2 Gene Is Modulated by Expression of Its Receptor in Vascular Endothelial Cells

1999 ◽  
Vol 254 (2) ◽  
pp. 292-298 ◽  
Author(s):  
Hiroyasu Inoue ◽  
Kazuhiko Umesono ◽  
Takeo Nishimori ◽  
Yukio Hirata ◽  
Tadashi Tanabe
Keyword(s):  
Endothelial Cells ◽  
Promoter Activity ◽  
Vascular Endothelial Cells ◽  
Cyclooxygenase 2 ◽  
Vascular Endothelial

scholarly journals Visualization of Proliferative Vascular Endothelial Cells in Tumors in Vivo by Imaging Their Partner of Sld5-1 Promoter Activity

2018 ◽  
Vol 188 (5) ◽  
pp. 1300-1314 ◽  
Author(s):  
Daishi Yamakawa ◽  
Weizhen Jia ◽  
Hiroyasu Kidoya ◽  
Shoko Hosojima ◽  
Miku Torigata ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Promoter Activity ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial

scholarly journals Hypoxia Induces Cyclooxygenase-2 via the NF-κB p65 Transcription Factor in Human Vascular Endothelial Cells

1997 ◽  
Vol 272 (1) ◽  
pp. 601-608 ◽  
Author(s):  
John F. Schmedtje ◽  
Yan-Shan Ji ◽  
W.-L. Liu ◽  
Raymond N. DuBois ◽  
Marschall S. Runge
Keyword(s):  
Endothelial Cells ◽  
Transcription Factor ◽  
Vascular Endothelial Cells ◽  
Cyclooxygenase 2 ◽  
Vascular Endothelial

scholarly journals Exogenous H2S Regulates of Cystathionine Gamma-Lyase in HUVECs During Hypoxia

2020 ◽  
Author(s):  
Maoxian Wang
Keyword(s):  
Endothelial Cells ◽  
Endothelial Cell ◽  
Mrna Expression ◽  
Blood Vessels ◽  
Western Blotting ◽  
Promoter Activity ◽  
Vascular Endothelial Cells ◽  
Vascular Endothelial Cell ◽  
Luciferase Assay ◽  
Vascular Endothelial

Cystathionine gamma-lyase (CSE) is one of the essential H2S-producing enzymes, and it regulates diverse functions in connection with cardiovascular function. It is crucial how exogenous H2S regulates CSE expression of the vascular endothelial cell during hypoxia. We examined the transcription and expression of CSE in HUVECs regulated by exogenous H2S with 100 μM during hypoxia by Luciferase assay, Western blotting, and quantitative RT-qPCR. Exogenous H2S influenced on the promoter activity of CSE in HUVECs during hypoxia. The effects of 100 μM H2S on CSE mRNA expression in HUVECs is decreased compared with 0 μM H2S. The consequences of 100 μM H2S on the expression level of CSE protein in HUVECs at two h of hypoxia is reduced compared with 0 μM H2S. These findings suggest that vascular endothelial cells can respond to the signals of hypoxia in the blood, and can respond to changes in H2S concentration in the blood, thus affect the blood vessels themselves.

Helicobacter pyloriinduces cyclooxygenase‐1 and cyclooxygenase‐2 expression in vascular endothelial cells

2003 ◽  
Vol 38 (10) ◽  
pp. 1023-1030 ◽  
Author(s):  
M. F. Byrne ◽  
J. F. Murphy ◽  
P. A. Corcoran ◽  
J. C. Atherton ◽  
K. M. Sheehan ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Vascular Endothelial Cells ◽  
Cyclooxygenase 2 ◽  
Vascular Endothelial ◽  
Cyclooxygenase 1
Sign in / Sign up

Export Citation Format

Share Document