scholarly journals Down-regulation of Bgp1a Viral Receptor by Interferon-γ Is Related to the Antiviral State and Resistance to Mouse Hepatitis Virus 3 Infection

Virology ◽  
2000 ◽  
Vol 274 (2) ◽  
pp. 278-283 ◽  
Author(s):  
Ruth C. Vassão ◽  
Milene T. de Franco ◽  
Dieter Hartz ◽  
Manuel Modolell ◽  
Albrecht E. Sippel ◽  
...  
Virology ◽  
1993 ◽  
Vol 196 (1) ◽  
pp. 45-56 ◽  
Author(s):  
Kyoko Yokomori ◽  
Miyuki Asanaka ◽  
Stephen A. Stohlman ◽  
Michael M.C. Lai

2004 ◽  
Vol 78 (14) ◽  
pp. 7828-7832 ◽  
Author(s):  
Chandran Ramakrishna ◽  
Cornelia C. Bergmann ◽  
Kathryn V. Holmes ◽  
Stephen A. Stohlman

ABSTRACT Detection of the mouse hepatitis virus receptor within the central nervous system (CNS) has been elusive. Receptor expression on microglia was reduced during acute infection and restored following immune-mediated virus control. Receptor down regulation was independent of neutrophils, NK cells, gamma interferon, or perforin. Infection of mice devoid of distinct inflammatory cells revealed CD4+ T cells as the major cell type influencing receptor expression by microglia. In addition to demonstrating receptor expression on CNS resident cells, these data suggest that transient receptor down regulation on microglia aids in establishing persistence in the CNS by assisting virus infection of other glial cell types.


1988 ◽  
Author(s):  
Joan M. Cook-Mills ◽  
Hidayatulla G. Munshi ◽  
Robert L. Perlman ◽  
Donald A. Chambers

1997 ◽  
Vol 46 (3) ◽  
pp. 211-218 ◽  
Author(s):  
Hodaka SUZUKI ◽  
Wijit KIATIPATTANASAKUL ◽  
Satoru KAJIKAWA ◽  
Shigeki TSUTSUI ◽  
Hiroyuki NAKAYAMA ◽  
...  

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