Restorative Therapies for Parkinson's Disease: Current Status and Future Perspectives

Author(s):  
Anders Björklund
2019 ◽  
Vol 120 (8) ◽  
pp. 12156-12166 ◽  
Author(s):  
Omid Reza Tamtaji ◽  
Mojtaba Naderi Taheri ◽  
Fahimeh Notghi ◽  
Reza Alipoor ◽  
Reihanesadat Bouzari ◽  
...  

2013 ◽  
Vol 18 (3-4) ◽  
pp. 155-162 ◽  
Author(s):  
Jian Wang ◽  
Jake G. Hoekstra ◽  
Chuantao Zuo ◽  
Travis J. Cook ◽  
Jing Zhang

2018 ◽  
Vol 3 (8) ◽  

Dance is basically a complex physical activity which either casually or formally organized in which people take part for fitness, health and well-being, social relationships or competition and a worldwide human activity that involves complex whole body movements through space synchronized to music. Dance-related reviews of evidence have examined the effectiveness of dance therapy on psychological and physical health and well-being outcomes in patients with cancer, for schizophrenia, and on depression. Dance therapy was officially described firstly in 1948. The medical application of dance therapy was well reviewed in neurologic conditions. Dance has been used extensively for the treatment of gait and balance dysfunction in individuals with Parkinson’s disease. Especially, Argentine tango is the most frequently employed dance form in the treatment of Parkinson’s disease. Tango therapy may hold promise as an intervention to improve gait, balance, and mobility in a variety of neurological conditions. Tango therapy was approached from dance therapy to the current status of medical application. A more systemic analysis of tango movement for proper and effective therapeutic application of tango is necessary for medical purposes.


2018 ◽  
Vol 19 (11) ◽  
pp. 3343 ◽  
Author(s):  
Emi Nagoshi

Parkinson’s disease (PD) is the most common cause of movement disorders and is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. It is increasingly recognized as a complex group of disorders presenting widely heterogeneous symptoms and pathology. With the exception of the rare monogenic forms, the majority of PD cases result from an interaction between multiple genetic and environmental risk factors. The search for these risk factors and the development of preclinical animal models are in progress, aiming to provide mechanistic insights into the pathogenesis of PD. This review summarizes the studies that capitalize on modeling sporadic (i.e., nonfamilial) PD using Drosophila melanogaster and discusses their methodologies, new findings, and future perspectives.


2016 ◽  
Vol 6 (4) ◽  
pp. 299-317 ◽  
Author(s):  
Kyle A Smith ◽  
Rajesh Pahwa ◽  
Kelly E Lyons ◽  
Jules M Nazzaro

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