Open Heart ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. e001499
Author(s):  
Stuart Pocock ◽  
David B Brieger ◽  
Ruth Owen ◽  
Jiyan Chen ◽  
Mauricio G Cohen ◽  
...  

ObjectiveTo assess associations of health-related quality of life (HRQoL) with patient profile, resource use, cardiovascular (CV) events and mortality in stable patients post-myocardial infarction (MI).MethodsThe global, prospective, observational TIGRIS Study enrolled 9126 patients 1–3 years post-MI. HRQoL was assessed at enrolment and 6-month intervals using the patient-reported EuroQol-5 dimension (EQ-5D) questionnaire, with scores anchored at 0 (worst possible) and 1 (perfect health). Resource use, CV events and mortality were recorded during 2-years’ follow-up. Regression models estimated the associations of index score at enrolment with patient characteristics, resource use, CV events and mortality over 2-years’ follow-up.ResultsAmong 8978 patients who completed the EQ-5D questionnaire, 52% reported ‘some’ or ‘severe’ problems on one or more health dimensions. Factors associated with a lower index score were: female sex, older age, obesity, smoking, higher heart rate, less formal education, presence of comorbidity (eg, angina, stroke), emergency room visit in the previous 6 months and non-ST-elevation MI as the index event. Compared with an index score of 1 at enrolment, a lower index score was associated with higher risk of all-cause death, with an adjusted rate ratio of 3.09 (95% CI 2.20 to 4.31), and of a CV event, with a rate ratio of 2.31 (95% CI 1.76 to 3.03). Patients with lower index score at enrolment had almost two times as many hospitalisations over 2-years’ follow-up.ConclusionsClinicians managing patients post-acute coronary syndrome should recognise that a poorer HRQoL is clearly linked to risk of hospitalisations, major CV events and death.Trial registration numberClinicalTrials.gov Registry (NCT01866904) (https://clinicaltrials.gov).


Author(s):  
Lisa Van Wilder ◽  
Rana Charafeddine ◽  
Philippe Beutels ◽  
Robin Bruyndonckx ◽  
Irina Cleemput ◽  
...  

Abstract Purpose Health-related quality of life outcomes are increasingly used to monitor population health and health inequalities and to assess the (cost-) effectiveness of health interventions. The EQ-5D-5L has been included in the Belgian Health Interview Survey, providing a new source of population-based self-perceived health status information. This study aims to estimate Belgian population norms for the EQ-5D-5L by sex, age, and region and to analyze its association with educational attainment. Methods The BHIS 2018 provided EQ-5D-5L data for a nationally representative sample of the Belgian population. The dimension scores and index values were analyzed using logistic and linear regressions, respectively, accounting for the survey design. Results More than half of respondents reported problems of pain/discomfort, while over a quarter reported problems of anxiety/depression. The average index value was 0.84. Women reported more problems on all dimensions, but particularly on anxiety/depression and pain/discomfort, resulting in significantly lower index values. Problems with mobility, self-care, and usual activities showed a sharp increase after the age of 80 years. Consequently, index values decreased significantly by age. Lower education was associated with a higher prevalence of problems for all dimensions except anxiety/depression and with a significantly lower index value. Conclusion This paper presents the first nationally representative Belgian population norms using the EQ-5D-5L. Inclusion of the EQ-5D in future surveys will allow monitoring over time of self-reported health, disease burden, and health inequalities.


2015 ◽  
Vol 40 (2) ◽  
pp. 264 ◽  
Author(s):  
Yuguang Zhang ◽  
Yaocheng Shi
Keyword(s):  

2019 ◽  
Vol 70 (2) ◽  
pp. 300
Author(s):  
F. A.B. Pereira ◽  
L. L. Luiz ◽  
S. R. Bruzaroski ◽  
R. C. Poli-Frederico ◽  
R. Fagnani ◽  
...  

The aim of this study was to evaluate the lipolytic index (LI) of Pseudomonas fluorescens and Pseudomonas putida (2, 5, 6 log CFU/mL) in milk during 96 h by the Lipo R method. The strains were isolated from refrigerated raw milk (30 °C, 48 h), and species were confirmed by PCR, inoculated in reconstituted whole milk, and stored at 2 °C, 4 °C, and 8 °C. The storage time (ST) and temperature were associated with LI of P. putida. The interaction among lipolysis, temperature, and ST occurs even with a low population of P. putida and these variables combined together contributed to about 77% of the free fatty acids (FFA) in milk. The ST, temperature, and population of P. fluorescens showed a significant effect on its LI, and the variables contributed to about 43% of FFA. LI was about 224% higher in milk with P. fluorescens than with P. putida. The reduc-tion in ST and milk temperature resulted in a decrease in lipid lysis and a lower index of FFA by P. putida and P. fluorescens, with P. fluorescens showing a higher lipolytic capacity.


2020 ◽  
Vol 87 ◽  
Author(s):  
Marcelo Feitosa da Silva ◽  
Marina Funichello ◽  
Diego Miranda de Souza

ABSTRACT The population of the caterpillar Diatraea saccharalis (Lepidoptera: Crambidae) has increased in the crop of sugarcane in recent years. Although the control of this insect is traditionally carried out through biological control, the use of phytosanitary products has still been necessary. Therefore, the goal of this work was to evaluate the performance of different insecticides in sugarcane borer control, as well as the effect on productivity and total recoverable sugar (TRS). The experiment was conducted in a randomized experimental delineation of blocks, with six treatments and four blocks. Treatments consisted of five insecticides and one control group (without application of insecticide). For calculating the D. saccharalis infestation index, monthly samplings were performed every 30 days, for 12 months. After this period, the final D. saccharalis infestation index was evaluated and calculated for each treatment. In order to compare productivity among procedures, four central lines were collected from each plot. Thus, the samples were weighed for the productivity calculation (TCH) and sent to the laboratory for the total recoverable sugar (TRS) analysis. The chloranthraniliprole (350) insecticide provided a lower index of sugarcane borer infestation, in addition to greater productivity when compared to the other insecticides. There was no significant difference in the parameter of total recoverable sugar (TRS) among treatments.


2008 ◽  
Vol 33 (12) ◽  
pp. 1288 ◽  
Author(s):  
Fangwei Ye ◽  
Yaroslav V. Kartashov ◽  
Victor A. Vysloukh ◽  
Lluis Torner
Keyword(s):  

2010 ◽  
Author(s):  
Yoshio Hayasaki ◽  
Takayuki Higuchi ◽  
Naoki Fukaya ◽  
Taku Kobayashi

2000 ◽  
Vol 21 ◽  
Author(s):  
Naresh Kazi Tamrakar

Clast morphology of the Siwalik conglomerates from the Dhan Khola Formation was studied at 19 horizons. The clasts were measured to calculate morphological indices such as axial ratios, c/a and (a-b)/(a-c), maximum projection sphericity (ψp), coefficient of flatness (CF), and roundness (p) separately for quartzite clasts (with two size-grades) and other clasts. The shape indices were plotted in shape diagrams and statistical tests were used to compare the shape indices of the above clasts with the index limits proposed in earlier studies. Based on clast type, four units are proposed for the Dhan Khola Formation. The formation is sub-divided into the volcanic clast-dominated, dolomite clast-dominated, quartzite clast-dominated, and terrigenous clast-dominated units, respectively from bottom to top. The latter unit contains many clasts derived from the Siwaliks. The quartzite clasts are more compact than other ones with significant differences in their axial ratios. The quartzite clasts show textural abnormalities and their p values decrease in the upper part of the formation suggesting high rate of sediment supply and nearness of complex source. The quartzite clasts with smaller (>-4ϕ) size-grade are better sphered. They plot clearly in the fluvial field of the ψp versus CF diagram. In 60 % of the quartzite clasts, means of ψp and CF exceed significantly the lower index limits showing that they were shaped in fluvial environment. However, the samples giving insignificant results could have also formed under the same conditions but with ψp and CF values lower than index limits proposed earlier.


Sign in / Sign up

Export Citation Format

Share Document