Parotid Gland and Other Salivary Gland Tumors

2011 ◽  
pp. 237-259
Author(s):  
Frédérique Dubrulle ◽  
Raphaëlle Souillard-Scemama
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Gland Tumors

scholarly journals Co-expression of Myoepithelial and Melanocytic Features in Carcinoma Ex Pleomorphic Adenoma

2021 ◽  
Author(s):  
Costantino Ricci ◽  
Federico Chiarucci ◽  
Francesca Ambrosi ◽  
Tiziana Balbi ◽  
Barbara Corti ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumors ◽  
Melanin Pigment ◽  
Carcinoma Ex Pleomorphic Adenoma ◽  
Pertinent Literature

AbstractThe presence of melanin pigment and melanocytic markers expression have been rarely reported in salivary gland tumors. Herein, two cases of carcinoma arising in pleomorphic adenoma of the parotid gland and showing diffuse expression of myoepithelial and melanocytic markers are described. The clinical-pathological clues useful in the differential diagnosis with melanoma are discussed. In addition, a review of the pertinent literature is also proposed, discussing the pathologic mechanisms potentially involved in this phenomenon.

scholarly journals Pattern of distribution of different salivary gland tumors; a retrospective study in NICRH, Dhaka

2016 ◽  
Vol 15 (1) ◽  
pp. 95-98
Author(s):  
Afroza Khanam ◽  
Gulshan Akhter ◽  
Md. Abdur Rahman
Keyword(s):  
Salivary Gland ◽  
Retrospective Study ◽  
Parotid Gland ◽  
Minor Salivary Gland ◽  
Salivary Gland Tumor ◽  
Salivary Gland Tumors ◽  
Major Salivary Gland ◽  
Gland Tumor ◽  
Minor Salivary Gland Tumors ◽  
Malignant Salivary Gland Tumors

Background: Salivary gland tumors are rare, generally benign and affect both major and minor salivary glands.Objective: To find out the pattern of distribution of different benign and malignant salivary gland epithelial tumors and their relation to age and sex in a tertiary care center in Bangladesh.Methodology: This is a retrospective study. Details of epithelial salivary gland tumors were obtained from department of ENT, National institute of cancer & research hospital (NICRH), Dhaka, Bangladesh from the period January 2009 to December 2012 (3 years).Result: A total number of 261 cases presenting with both benign and malignant salivary gland tumors were analyzed according to gender, age and histopathological findings. There were 130 (49.84%) males and 131 (50.19%) females with the male female ration of 1: 0.99. Age of study population ranged from 10 to 70 years with the mean age 40.78. Percentage of benign salivary gland tumors was 73.94% and malignant salivary gland tumor 26.05%. Among major salivary gland tumors, no sublingual tumors were found and parotid gland tumors were the commonest. Whereas, among minor salivary gland tumors palatal minor salivary tumors were common.Conclusion: Parotid gland was the most common site of origin of both benign and malignant salivary gland tumors. Histopathologically, pleomorphic adenoma was the most common benign salivary gland tumor and mucoepidermoid carcinoma was the most frequent malignant neoplasm. Adenoid cystic carcinoma was common minor salivary gland tumor.Bangladesh Journal of Medical Science Vol.15(1) 2016 p.90-94

Salivary gland tumors of the parotid gland: CT and MR imaging findings with emphasis on intratumoral cystic components

2014 ◽  
Vol 56 (9) ◽  
pp. 789-795 ◽  
Author(s):  
Hiroki Kato ◽  
Masayuki Kanematsu ◽  
Haruo Watanabe ◽  
Keisuke Mizuta ◽  
Mitsuhiro Aoki
Keyword(s):  
Salivary Gland ◽  
Mr Imaging ◽  
Parotid Gland ◽  
Salivary Gland Tumors ◽  
Imaging Findings

scholarly journals Salivary gland tumours: a retrospective study at a tertiary care centre in South India

2021 ◽  
Vol 7 (5) ◽  
pp. 825
Author(s):  
Neha Swarnkar ◽  
Srinivasan Venkataraman ◽  
Prasanna Kumar Saravanam
Keyword(s):  
Salivary Gland ◽  
Retrospective Study ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
South India ◽  
Tertiary Care ◽  
Salivary Gland Tumors ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Salivary Gland Tumours

<p><strong>Background:</strong> Salivary gland tumors are morphologically and histologically diverse group of lesions and their frequency varies in several parts of the world. Better understanding of these tumours will help in assessing the behaviour and outcomes of lesions of this region. The aim of this study was to analyse the charactertistics of different tumours occurring in the salivary gland in a tertiary care centre in South India.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted of salivary gland tumors diagnosed from the year 2015 to 2020. Patient age and gender, tumor site and frequency, histopathological diagnosis were evaluated and analysed.</p><p class="abstract"><strong>Results:</strong> A total of 36 salivary gland tumor cases was identified, 30 (87.3%) of which were classified as benign and 6 (12.7%) as malignant. Most tumors occurred in the parotid gland (81.3%). Pleomorphic adenoma was the most common tumor in 23 patients (63.8%), followed by warthins tumour. The tumors occurred more often in women than men.</p><p><strong>Conclusion: </strong>The results of the present study reinforce prevalence of salivary gland tumours. The parotid gland is the most common location and pleomorphic adenoma are the most frequent lesions. The malignant tumors also can occur in these glands and good clinical suspicion is necessary.</p><p class="abstract"> </p>

Major salivary gland tumors in children — diagnostic and therapeutic difficulties

Open Medicine ◽  
2012 ◽  
Vol 7 (5) ◽  
pp. 624-627
Author(s):  
Rafal Zielinski ◽  
Anna Zakrzewska
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Treatment Method ◽  
Needle Aspiration ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Major Salivary Gland ◽  
Tumor Treatment ◽  
Total Parotidectomy ◽  
Operational Methods

AbstractMajor salivary gland tumors are very rare in the developmental period. Confirming tumor changes of the salivary gland requires precise diagnostic imaging involving an ultrasonography scan, computed tomography and magnetic resonance. A needle aspiration biopsy (NAB) of a tumor is of high importance. Excision of the tumor is the main treatment method in the case of parotid gland tumors. Statistical data concerning tumors suggest choosing less invasive methods, which seems very logical in children. The operational methods used in the tumor treatment are: extracapsular excision of a tumor, partial parotidectomy, total parotidectomy, sometimes proceeded with lymphatic nodes operations. Extracapsular excision of a tumor is a noninvasive method chosen because of simplicity and lesser risk of serious complications. This method is reserved only for the cases of benign tumors of the gland. Most authors, however, consider a partial parotidectomy as a method of choice in benign tumor cases and a total parotidectomy in cases of carcinomas of the parotid gland. Submandibular gland tumors need total gland excision. The clinical cases presented in this paper show the difficulties in diagnosis and treatment choices in cases of major salivary gland tumors in children.

scholarly journals Oncocytoma Parotid Gland: A Case Report and Brief Review of Literature

2014 ◽  
Vol 5 (1) ◽  
pp. 25-27
Author(s):  
Sunil Kumar ◽  
Ashwini Sethi ◽  
Satwinder Pal Singh
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Salivary Gland Tumors ◽  
Review Of Literature ◽  
Head Neck

ABSTRACT Very few cases of oncocytoma parotid have been reported in literature. Because of its rarity (less than 1% of salivary gland tumors) and clinical presentation of the tumor, there is a tendency among the clinicians to misdiagnose it as pleomorphic adenoma, hemangioma or other forms of oncocytosis. Only a histopathological examination can confirm it. We report here a case of oncocytoma of parotid gland in a 70-year-old male who had the tumor for over 9 years. How to cite this article Kumar S, Sethi A, Singh SP, Sharma V. Oncocytoma Parotid Gland: A Case Report and Brief Review of Literature. Int J Head Neck Surg 2014;5(1):25-27.

Basal Cell Adenocarcinoma of the Parotid Gland

1996 ◽  
Vol 115 (1) ◽  
pp. 150-151 ◽  
Author(s):  
Ashutosh Kacker ◽  
Volkan Adsay ◽  
Arnold Komisar
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Basal Cell ◽  
Malignant Neoplasm ◽  
Growth Characteristics ◽  
Salivary Gland Tumors ◽  
Single Type ◽  
Basal Cell Adenoma ◽  
Cell Adenoma ◽  
Basal Cell Adenocarcinoma

The term basal cell adenoma was used by Kleinsasser and Klien 1 in 1967 to describe benign salivary gland tumors comprised of a single type of epithelium. Basal cell adenocarcinoma is a relatively new entity, and there are only a few cases reported in the literature. It has a morphology like that of a basal cell adenoma but has growth characteristics of a malignant neoplasm.

Oncocytic Neoplasms of the Parotid Gland: A 16-Year Institutional Review

2002 ◽  
Vol 126 (6) ◽  
pp. 657-662 ◽  
Author(s):  
Randolph B. Capone ◽  
Patrick K. Ha ◽  
William H. Westra ◽  
Thomas M. Pilkington ◽  
James J. Sciubba ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Mitochondrial Dysfunction ◽  
Control Region ◽  
Genetic Alterations ◽  
Salivary Gland Tumors ◽  
Oncocytic Carcinoma ◽  
Mtdna Mutations ◽  
Institutional Review ◽  
Plausible Mechanism

BACKGROUND: Oncocytic neoplasms of the parotid gland are a rare collection of salivary gland tumors that include oncocytosis, oncocytoma, and oncocytic carcinoma. Mounting evidence has linked the presence of oncocytes to acquired mitochondrial dysfunction. OBJECTIVES: The study goals were to further delineate this poorly understood group of salivary gland tumors and to search for genetic alterations indicative of mitochondrial dysfunction. METHODS: Cases were identified by search of the surgical pathology archival files from 1984 through 2000. Corresponding medical records were reviewed. Tumor mitochondrial DNA (mtDNA) was evaluated for mtDNA mutations within the control region (C-tract). RESULTS: Twenty-one parotid oncocytic neoplasms were identified. Oncocytoma was the most frequent morphology (62%), followed by oncocytosis (28.5%) and oncocytic carcinoma (9.5%). One specimen displayed synchronous oncocytic morphologies (oncocytoma, oncocytosis, and oncocytic metaplasia). One oncocytoma specimen displayed the mtDNA C-tract alteration. CONCLUSIONS: Oncocytic neoplasia of the parotid gland is a rare form of salivary gland disease with obscure etiology. The presence of multiple oncocytic morphologies in a single specimen is suggestive of transition between forms. Although oncocytic tumorigenesis secondary to acquired mitochondrial dysfunction is a plausible mechanism, few of these tumors actually harbor mtDNA alterations within the control region.

scholarly journals Mucoepidermoid Carcinoma: A Demographic and Histopathological Profile

2020 ◽  
Vol 9 (4) ◽  
pp. 298-302
Author(s):  
Zainab Niazi
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Mucoepidermoid Carcinoma ◽  
Salivary Gland Tumors ◽  
Anatomical Site ◽  
Low Grade ◽  
High Grade ◽  
Male Patients ◽  
Histopathological Grading ◽  
Malignant Salivary Gland Tumors

Background: To find the frequency and clinico-pathological presentation of mucoepidermoid carcinoma (MEC).Materials and Methods:In this study, we included all the malignant salivary gland tumors. Among these the frequency of mucoepidermoid carcinoma was considered. Age, gender, histopathological grading and anatomical site of tumor were included in data analysis.Results:Out of 60 malignant salivary gland tumors reported to the histopathology department, 30 tumors were diagnosed as mucoepidermoid carcinomas. The patient’s age having mucoepidermoid carcinoma ranged from 6 to 88 years, mean age of 44.9±19.2SD. The male patients were 23 in number while female were 7. Out of 30 cases, 73.3% patients had tumor in parotid gland, while13.3% patients in submandibular gland . Other tumors were in palate, retromolar area, and in posterior 1/3rdof tongue (13.3%). According to histopathological grading 26.6% cases of MEC were of high grade, 26.6 % were intermediate grade and 36.6% were low grade.Conclusions:According to this study, the frequency of MEC was 50% among all salivary gland tumors. MEC was mostly found in parotid gland and histopathologically low grade type was the most common.

scholarly journals Histopathological spectrum and outcome of surgery for salivary gland tumors presented in tertiary care hospital of Pakistan.

2021 ◽  
Vol 28 (10) ◽  
pp. 1418-1421
Author(s):  
Ahmed Siddique Ammar ◽  
Rizwan Khalid ◽  
Syed Asghar Naqi ◽  
Shehrbano Khattak ◽  
Farwa Inayat ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Benign Tumor ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Salivary Gland Tumors ◽  
Care Hospital ◽  
Outcome Of Surgery ◽  
Malignant Salivary Gland Tumors

Objective: This study is aimed to know the histopathological spectrum and outcome of surgery for salivary gland tumors presented in a tertiary care hospital of Pakistan. Study Design: Retrospective study. Setting: Tertiary Care Hospital of Pakistan. Period: July 2018 to June 2020. Material & Methods: After approval from Institutional Review Board. Total 73 patients were selected with preoperative diagnosis of salivary gland tumors with consecutive non probability sampling. All surgical procedures were done by specialist general surgeons who had experience of more than 10 years of head and neck surgery. Results: Male to female ratio was 2:1 with mean age of patients was 46 years. Among males 29 (59.1%) were benign salivary gland tumors while 20 (40.81%) were malignant salivary gland tumors. Among females 13 (54.16%) were benign and 11 (45.83%) were malignant salivary gland tumors Most common benign tumor was pleomorphic adenoma 32 (43.8%) while mucoepidermoid carcinoma was most common malignant tumor 17 (23.28%). Only 9 (12.32%) patients experienced nerve paresis. Conclusion: Male preponderance, a relatively younger age at presentation and single predominant benign tumor (pleomorphic adenoma) were the significant findings. Majority of them were found in parotid gland and found to be benign in nature. Majority of them were found in parotid gland and found to be benign in nature. Although fine needle aspiration cytology and magnetic resonance imaging provide some useful information about the nature of tumor but most of them will acquire a surgical excision in order to find the definitive diagnosis.

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