Magnetic Resonance Imaging for Small-Bowel-Related Diagnosis Contrast Agents and MR Angiographic Techniques

Author(s):  
Evan S. Siegelman ◽  
Pablo R. Ros
2019 ◽  
Author(s):  
Hamilton Lee ◽  
Jenica Lumata ◽  
Michael A. Luzuriaga ◽  
Candace Benjamin ◽  
Olivia Brohlin ◽  
...  

<div><div><div><p>Many contrast agents for magnetic resonance imaging are based on gadolinium, however side effects limit their use in some patients. Organic radical contrast agents (ORCAs) are potential alternatives, but are reduced rapidly in physiological conditions and have low relaxivities as single molecule contrast agents. Herein, we use a supramolecular strategy where cucurbit[8]uril binds with nanomolar affinities to ORCAs and protects them against biological reductants to create a stable radical in vivo. We further over came the weak contrast by conjugating this complex on the surface of a self-assembled biomacromolecule derived from the tobacco mosaic virus.</p></div></div></div>


2021 ◽  
Vol 57 (14) ◽  
pp. 1770-1773
Author(s):  
S. A. Amali S. Subasinghe ◽  
Jonathan Romero ◽  
Cassandra L. Ward ◽  
Matthew D. Bailey ◽  
Donna R. Zehner ◽  
...  

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry.


Author(s):  
Anton Popov ◽  
Maxim Artemovich Abakumov ◽  
Irina Savintseva ◽  
Artem Ermakov ◽  
Nelly Popova ◽  
...  

Gd-based complexes are widely used as magnetic resonance imaging (MRI) contrast agents. The safety of previously approved contrast agents is questionable and is being re-assessed. The main causes of concern...


2021 ◽  
pp. 2101019
Author(s):  
Sandra Díez‐Villares ◽  
Miguel A. Ramos‐Docampo ◽  
Andrés da Silva‐Candal ◽  
Pablo Hervella ◽  
Abi J. Vázquez‐Ríos ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1230
Author(s):  
Vega Lloveras ◽  
José Vidal-Gancedo

The search for new biomedical applications of dendrimers has promoted the synthesis of new radical-based molecules. Specifically, obtaining radical dendrimers has opened the door to their use in various fields such as magnetic resonance imaging, as anti-tumor or antioxidant agents, or the possibility of developing new types of devices based on the paramagnetic properties of organic radicals. Herein, we present a mini review of radical dendrimers based on polyphosphorhydrazone, a new type of macromolecule with which, thanks to their versatility, new metal-free contrast agents are being obtained, among other possible applications.


2021 ◽  
Vol 4 (2) ◽  
pp. 1235-1242
Author(s):  
Armita Dash ◽  
Barbara Blasiak ◽  
Boguslaw Tomanek ◽  
Abhinandan Banerjee ◽  
Simon Trudel ◽  
...  

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