A Workflow for the Identification of Mycotoxin Metabolites Using Liquid Chromatography–Ion Mobility-Mass Spectrometry

2019 ◽  
pp. 133-144
Author(s):  
Laura Righetti ◽  
Chiara Dall’Asta
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry

scholarly journals Ion Mobility–Mass Spectrometry for Bioanalysis

Separations ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 33
Author(s):  
Xavier Garcia ◽  
Maria del Mar Sabaté ◽  
Jorge Aubets ◽  
Josep Maria Jansat ◽  
Sonia Sentellas
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Biological Samples ◽  
Ion Mobility Mass Spectrometry ◽  
Exogenous Compounds ◽  
Analytical Separation

This paper aims to cover the main strategies based on ion mobility spectrometry (IMS) for the analysis of biological samples. The determination of endogenous and exogenous compounds in such samples is important for the understanding of the health status of individuals. For this reason, the development of new approaches that can be complementary to the ones already established (mainly based on liquid chromatography coupled to mass spectrometry) is welcomed. In this regard, ion mobility spectrometry has appeared in the analytical scenario as a powerful technique for the separation and characterization of compounds based on their mobility. IMS has been used in several areas taking advantage of its orthogonality with other analytical separation techniques, such as liquid chromatography, gas chromatography, capillary electrophoresis, or supercritical fluid chromatography. Bioanalysis is not one of the areas where IMS has been more extensively applied. However, over the last years, the interest in using this approach for the analysis of biological samples has clearly increased. This paper introduces the reader to the principles controlling the separation in IMS and reviews recent applications using this technique in the field of bioanalysis.

Rapid Quantitation of 25-Hydroxyvitamin D2 and D3 in Human Serum Using Liquid Chromatography/Drift Tube Ion Mobility-Mass Spectrometry

2019 ◽  
Vol 91 (21) ◽  
pp. 13555-13561 ◽  
Author(s):  
Nicholas R. Oranzi ◽  
Jiajun Lei ◽  
Robin H. J. Kemperman ◽  
Christopher D. Chouinard ◽  
Brett Holmquist ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Human Serum ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry

scholarly journals Determining Double Bond Position in Lipids Using Online Ozonolysis Coupled to Liquid Chromatography and Ion Mobility-Mass Spectrometry

2018 ◽  
Vol 90 (3) ◽  
pp. 1915-1924 ◽  
Author(s):  
Rachel A. Harris ◽  
Jody C. May ◽  
Craig A. Stinson ◽  
Yu Xia ◽  
John A. McLean
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Double Bond ◽  
Ion Mobility ◽  
Double Bond Position ◽  
Ion Mobility Mass Spectrometry

Liquid chromatography–drift tube ion mobility–mass spectrometry as a new challenging tool for the separation and characterization of silymarin flavonolignans

2020 ◽  
Vol 412 (4) ◽  
pp. 819-832 ◽  
Author(s):  
Marie Fenclova ◽  
Milena Stranska-Zachariasova ◽  
Frantisek Benes ◽  
Alena Novakova ◽  
Petra Jonatova ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Mobility ◽  
Drift Tube ◽  
Ion Mobility Mass Spectrometry

Profiling of the known-unknown Passiflora variant complement by liquid chromatography - Ion mobility - Mass spectrometry

Talanta ◽  
2021 ◽  
Vol 221 ◽  
pp. 121311
Author(s):  
Michael McCullagh ◽  
Jeff Goshawk ◽  
David Eatough ◽  
Russell J. Mortishire-Smith ◽  
Cintia AM. Pereira ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Mobility ◽  
Ion Mobility Mass Spectrometry
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