Impact of a History of Caloric Restriction and a Frustration Stress Manipulation on Binge-Like Eating Behavior in Female Rats: Preclinical Results

2020 ◽  
pp. 239-260
Author(s):  
Maria Vittoria Micioni Di Bonaventura ◽  
Emanuela Micioni Di Bonaventura ◽  
Luca Botticelli ◽  
Carlo Cifani
Keyword(s):  
Caloric Restriction ◽  
Eating Behavior ◽  
Female Rats ◽  
History Of

Sexual dimorphism in liver mitochondrial oxidative capacity is conserved under caloric restriction conditions

2007 ◽  
Vol 293 (4) ◽  
pp. C1302-C1308 ◽  
Author(s):  
A. Valle ◽  
R. Guevara ◽  
F. J. García-Palmer ◽  
P. Roca ◽  
J. Oliver
Keyword(s):  
Sexual Dimorphism ◽  
Energy Expenditure ◽  
Oxidative Damage ◽  
Caloric Restriction ◽  
Oxidative Capacity ◽  
Complex Iii ◽  
Female Rats ◽  
Oxidative Balance ◽  
Wide Range ◽  
Mitochondrial Oxidative Capacity

Caloric restriction (CR) without malnutrition has been shown to increase maximal life span and delay the rate of aging in a wide range of species. It has been proposed that reduction in energy expenditure and oxidative damage may explain the life-extending effect of CR. Sex-related differences also have been shown to influence longevity and energy expenditure in many mammalian species. The aim of the present study was to determine the sex-related differences in rat liver mitochondrial machinery, bioenergetics, and oxidative balance in response to short-term CR. Mitochondria were isolated from 6-mo-old male and female Wistar rats fed ad libitum or subjected to 40% CR for 3 mo. Mitochondrial O2 consumption, activities of the oxidative phosphorylation system (complexes I, III, IV, and V), antioxidative activities [MnSOD, glutathione peroxidase (GPx)], mitochondrial DNA and protein content, mitochondrial H2O2 production, and markers of oxidative damage, as well as cytochrome C oxidase and mitochondrial transcription factor A levels, were measured. Female rats showed a higher oxidative capacity and GPx activity than males. This sexual dimorphism was not modified by CR. Restricted rats showed slightly increased oxygen consumption, complex III activity, and GPx antioxidant activity together with lower levels of oxidative damage. In conclusion, the sexual dimorphism in liver mitochondrial oxidative capacity was unaffected by CR, with females showing higher mitochondrial functionality and ROS protection than males.

The role of family history of disease and personal morbidity in eating behavior

1992 ◽  
Vol 7 (1) ◽  
pp. 3-14 ◽  
Author(s):  
Reinhard Fuchs ◽  
Richard M. Levinson ◽  
Gregory W. Heath ◽  
Frances C. Wheeler
Keyword(s):  
Family History ◽  
Eating Behavior ◽  
History Of Disease ◽  
History Of

scholarly journals Features of psychoemotional status and eating disorders in patients with gastroesophageal reflux disease and obesity

2021 ◽  
Vol 23 (5) ◽  
pp. 412-416
Author(s):  
Georgy L. Yurenev ◽  
◽  
Ekaterina M. Mironova ◽  
Natalia A. Sirota ◽  
Tamara V. Yureneva-Tkhorzhevskaya ◽  
...  
Keyword(s):  
Risk Factors ◽  
Eating Disorders ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Eating Behavior ◽  
Reflux Disease ◽  
Anxiety And Depression ◽  
Obese Patients ◽  
History Of ◽  
Depressive States

Background. Eating disorders, as well as features of the psychoemotional status as risk factors for obesity, patients with comorbid gastroesophageal reflux disease (GERD) and obesity in the modern literature are not sufficiently disclosed. Further study of these aspects may be one of the additional ways to improve the prognosis of the course of GERD, as well as the correction of the psychoemotional status of patients. Aim. To study the features of the course of GERD in concomitant obesity in the context of the peculiarities of the psychoemotional sphere, as well as to identify the types of eating disorders in this cohort of patients. Materials and methods. The study included 130 patients aged 24 to 72 years with complaints characteristic of the pathology of the upper digestive tract, who, along with a detailed analysis of complaints in order to verify the diagnosis and identify the features of the course of the disease, were tested with the Dutch Eating Behavior Questionnaire (DEBQ) and the hospital scale of anxiety and depression (HADS). Results. It was found that obese patients who had GERD less than 8 years ago were more likely to suffer from external and emotionogenic eating disorders, and the external type was more often associated with the male, and the emotionogenic type with the female sex. Whereas, in patients with obesity and a history of GERD for more than 8 years, the restrictive and emotionogenic types of eating disorders were relatively more often recorded. An increased level of anxiety in patients with GERD was noted, both against the background of obesity and without it, but those with comorbid pathology had a relatively higher score on the anxiety scale. Conclusion. Correction of eating behavior and signs of anxiety-depressive states in patients can open up new prospects for the fight against obesity. And this, in turn, can improve the prognosis of patients with GERD.

scholarly journals The age-related paraoxonase 1 response is altered by long-term caloric restriction in male and female rats

2006 ◽  
Vol 47 (9) ◽  
pp. 2042-2048 ◽  
Author(s):  
Elena Thomàs-Moyà ◽  
Magdalena Gianotti ◽  
Ana M. Proenza ◽  
Isabel Lladó
Keyword(s):  
Caloric Restriction ◽  
Female Rats ◽  
Paraoxonase 1 ◽  
Male And Female ◽  
Male And Female Rats ◽  
Age Related

scholarly journals Aripiprazole induced compulsive eating in adolescent: Is this the effect of aripiprazole on Serotonin receptors?

2020 ◽  
Vol 5 (7) ◽  
Keyword(s):  
Eating Behavior ◽  
Case History ◽  
Serotonin Receptors ◽  
Adolescent Male ◽  
Compulsive Eating ◽  
History Of ◽  
New Onset

Objective: To present a case of new onset Aripiprazole induced compulsive eating in an adolescent male. Method: We describe a case history of an adolescent male treated with Aripiprazole who developed compulsive eating behavior. Result: The compulsive eating behavior stopped once the Aripiprazole was discontinued. Conclusion: We argue that the compulsive eating behavior in the adolescent male was induced by Aripiprazole and the effect of Aripiprazole on eating behavior may be due to the effect of Aripiprazole on serotonin receptors.

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