Structural and Functional Characterization of Cyclic GMP-Stimulated Phosphodiesterases and Their Role in Intracellular Signal Transduction

1990 ◽  
pp. 281-289 ◽  
Author(s):  
R. T. Mac Farland ◽  
S. D. Stroop ◽  
J. A. Beavo
Keyword(s):  
Signal Transduction ◽  
Cyclic Gmp ◽  
Functional Characterization ◽  
Intracellular Signal Transduction ◽  
Intracellular Signal

Starling's law and intracellular signal transduction in 4 patients with Bland-White-Garland's syndrome

2004 ◽  
Vol 52 (S 1) ◽  
Author(s):  
N Kayhan ◽  
K Sonnenberg ◽  
A Bonz ◽  
G Reinerth ◽  
S Hagl ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Intracellular Signal Transduction ◽  
Starling’S Law ◽  
Intracellular Signal

Specific Features of Intracellular Signal Transduction in the Regulation of Functions of Neural Stem Cells and Committed Neuronal Progenitors

2021 ◽  
Vol 170 (4) ◽  
pp. 522-527
Author(s):  
G. N. Zyuz’kov ◽  
L. A. Miroshnichenko ◽  
T. Yu. Polyakova ◽  
V. V. Zhdanov ◽  
E. V. Simanina ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Stem Cells ◽  
Neural Stem Cells ◽  
Intracellular Signal Transduction ◽  
Neuronal Progenitors ◽  
Intracellular Signal

scholarly journals The p53 Protein Family in the Response of Tumor Cells to Ionizing Radiation: Problem Development

Acta Naturae ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 65-76
Author(s):  
Oleg A. Kuchur ◽  
Daria O. Kuzmina ◽  
Marina S. Dukhinova ◽  
Alexandr A. Shtil
Keyword(s):  
Signal Transduction ◽  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Tumor Cells ◽  
P53 Protein ◽  
Intracellular Signal Transduction ◽  
Radiation Problem ◽  
The Family ◽  
Intracellular Signal ◽  
Survival Mechanisms

Survival mechanisms are activated in tumor cells in response to therapeutic ionizing radiation. This reduces a treatments effectiveness. The p53, p63, and p73 proteins belonging to the family of proteins that regulate the numerous pathways of intracellular signal transduction play a key role in the development of radioresistance. This review analyzes the p53-dependent and p53-independent mechanisms involved in overcoming the resistance of tumor cells to radiation exposure.

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