A consolidated review of the current-state-of-the-art on optimal damper positioning techniques is presented in this chapter. The inherent assumptions made in previous research are discussed and substantiated with numerical studies. Earlier studies have shown that optimal distribution of dampers is sensitive to in-structure damping. In this chapter the significance of optimal distribution of dampers coupled with the necessity for the use of a more realistic in-structure damping model is qualitatively illustrated using a comparative sensitivity study. The effect of inherent assumption of linearity of the parent frame on the ‘optimality’ is also investigated. It is shown that linearity assumption imposed on the parent frame in a major seismic event may not be justified; thereby raising doubts on the scope of optimality techniques proposed in literature.