The Epidemiology of Cirrhosis of the Liver: A Statistical Analysis of Mortality Data with Special Reference to Canada

1977 ◽  
pp. 1-26 ◽  
Author(s):  
W. Schmidt
1990 ◽  
Vol 132 (supp1) ◽  
pp. 116-122 ◽  
Author(s):  
LAWRENCE P. HANRAHAN ◽  
IRENE MIRKIN ◽  
JOSEPH OLSON ◽  
HENRY A. ANDERSON ◽  
BETH J. FIORE

Abstract Increasingly, health departments are being pressed by the public to respond to disease risk with cluster investigations in communities and neighborhoods. This is a direct result of growing concern about the role that the environment may play in disease risk. While extensive analyses directly inputing exposures or numbers at risk are often necessary to thoroughly investigate clusters, it is quite useful to perform an exploratory analysis with existing morbidity and mortality data as a first level of response. To meet this need for timely evaluation, the authors describe a user-friendly Statistical Analysis System (SAS) program called SMRFIT to automate community disease cluster evaluations. The program creates frequency tables for number at risk and number of disease outcomes for the community, balance of parent county, and balance of state. SMRFIT then constructs standardized mortality ratios, with the community compared with balance of county and balance of state referents. Poisson regression is offered as an option for the modeling of community disease rates.


1955 ◽  
Vol 53 (3) ◽  
pp. 261-275 ◽  
Author(s):  
A. E. Pierce

Summary1. The lacto-globulin in bovine colostral whey, and the γ globulin in the serum contain the normal and induced agglutinins to the protozoon Trichomonas foetus.2. A decline in γ globulin in sera from cattle approaching calving may be associated with the concentration of the lacto-globulin in the udder.3. The elimination of the passive normal and induced agglutinins acquired by the neonatal calf was logarithmic. The autogenous production of γ globulin by the calf occurred soon after birth, resulting in an apparent decline in the rate of elimination of the lacto-globulins.4. The autogenous production of γ globulin was not necessarily accompanied by that of detectable normal agglutinin.5. Calves injected with T. foetus antigen within the first 3 weeks of life, and in which there was evidence of autogenous γ globulin, developed normal autogenous but not induced agglutinins.6. Calves which received colostrum containing maternal induced and normal agglutinins, calves partially deprived of colostrum, and calves immunized in early life, produced the normal autogenous agglutinin between the 30th and 60th days, reaching the normal adult titre of 1/48–1/96.7. The properties of the normal agglutinins were investigated. They possess some characteristics significantly different from those of the induced agglutinins. These suggested that the normal agglutinins were γ globulin molecules with an ‘accidental’ genetic configuration complementary to T. foetus.The author wishes to thank Dr M. Robertson, F.R.S., and Sir Alan Drury, F.R.S. for their interest and encouragement during the course of this work, and Dr R. C. Campbell for the statistical analysis.


Author(s):  
Filomena Maggino

In the sphere of social research, one of the principal methodological approaches is that of the survey. In the performance of surveys, statistics play a fundamental role. This publication is intended to highlight this role, with special reference to data analysis, placing the emphasis on the objectives of such analysis, the logic, the procedures necessary to achieve them, and the interpretation of results. The material has been divided into two volumes, which while being independent are also logically connected. The first volume is organised in two sections: the first is designed to provide a synthetic overview of the statistical survey in terms of methods and instruments, while the second describes the principal instruments of statistical analysis which enable a description of the data. The first volume comes complete with a CD with hypertext. The second volume presents the statistical approaches which enable the achievement of specific objectives, seen in terms of data exploration and verification of the results obtained.


1973 ◽  
Vol 30 (03) ◽  
pp. 480-493 ◽  
Author(s):  
Mircea P. Cucuianu ◽  
Vasile V. Vasile ◽  
Titus A. Popescu ◽  
Augustin Opincaru ◽  
Ion Crîsnic ◽  
...  

SummaryFactor XIII, estimated according to the method of Heene, was found to be diminished in patients with cirrhosis of the liver, in acute renal failure and, to a lesser extent, postoperatively, owing probably to both a decreased synthesis and an accelerated utilization. When compared to values obtained in healthy, normal weight, normolipemic control subjects, the level of factor XIII was higher in hyperlipemic and especially in hypertriglyceridemic patients, whether clinical atherosclerosis was present or not. Low levels of factor XIII were usually accompanied by a decrease in serum pseudocholinesterase, while high values of this enzyme produced by the liver were noted in hypertriglyceridemic patients. The hypothesis of an enhanced synthesis of factor XIII by the liver, in subjects with endogenous hypertriglyceridemia is considered. It is also suggested that accelerated stabilization of fibrin might contribute to the fibrinolytic insufficiency of hyperlipemic patients and enhance certain atherogenic mechanisms.


2005 ◽  
Author(s):  
Filomena Maggino

In the sphere of social research, one of the principal methodological approaches is that of the survey. In the performance of surveys, statistics play a fundamental role. This publication is intended to highlight this role, with special reference to data analysis, placing the emphasis on the objectives of such analysis, the logic, the procedures necessary to achieve them, and the interpretation of results. The material has been divided into two volumes, which while being independent are also logically connected. The first volume is organised in two sections: the first is designed to provide a synthetic overview of the statistical survey in terms of methods and instruments, while the second describes the principal instruments of statistical analysis which enable a description of the data. The first volume comes complete with a CD with hypertext. The second volume presents the statistical approaches which enable the achievement of specific objectives, seen in terms of data exploration and verification of the results obtained.


Sign in / Sign up

Export Citation Format

Share Document