Adhesion Molecules at Endothelial Cell to Cell Junctions

1993 ◽  
pp. 149-163
Author(s):  
Maria Grazia Lampugnani ◽  
Massimo Resnati ◽  
Marco Raiteri ◽  
Marco Pittiglio ◽  
Luigi Ruco ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Adhesion Molecules ◽  
Cell Junctions

Vascular and epithelial junctions: a barrier for leucocyte migration

2008 ◽  
Vol 36 (2) ◽  
pp. 203-211 ◽  
Author(s):  
Sarah Garrido-Urbani ◽  
Paul F. Bradfield ◽  
Boris P.-L. Lee ◽  
Beat A. Imhof
Keyword(s):  
Endothelial Cell ◽  
Adhesion Molecules ◽  
Adhesion Molecule ◽  
Cell Junctions ◽  
Mucosal Tissues ◽  
Platelet Endothelial Cell Adhesion ◽  
Leucocyte Migration ◽  
Epithelial Junctions ◽  
Epithelial Barriers ◽  
Underlying Mechanisms

Rapid mobilization of leucocytes through endothelial and epithelial barriers is key in immune system reactivity. The underlying mechanisms that regulate these processes have been the basis for many recent studies. Traditionally, leucocyte extravasation had been believed to occur through a paracellular route, which involves localized disruption of endothelial cell junctions. However, more recently, a transcellular route has been described involving the passage through the endothelial cell body. Leucocytes are also able to migrate through epithelium to monitor mucosal tissues and microenvironments. A number of adhesion molecules are known to regulate transmigration of leucocytes through epithelial and endothelial layers. Paracellular and transcellular leucocyte transmigration are regulated by adhesion molecules such as PECAM-1 (platelet–endothelial cell adhesion molecule 1), CD99, VE-cadherin (vascular endothelial cadherin) and JAM (junctional adhesion molecule) proteins. The purpose of this review is to discuss the role of these molecules in leucocyte transmigration and how they contribute to the different mechanisms that regulate leucocyte trafficking.

scholarly journals Angiomotin Regulates Endothelial Cell-Cell Junctions and Cell Motility

2005 ◽  
Vol 280 (41) ◽  
pp. 34859-34869 ◽  
Author(s):  
Anders Bratt ◽  
Olivier Birot ◽  
Indranil Sinha ◽  
Niina Veitonmäki ◽  
Karin Aase ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Cell Motility ◽  
Cell Junctions ◽  
Cell Cell

scholarly journals Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier

2008 ◽  
Vol 6 (3) ◽  
pp. 179-192 ◽  
Author(s):  
Svetlana Stamatovic ◽  
Richard Keep ◽  
Anuska Andjelkovic
Keyword(s):  
Endothelial Cell ◽  
Blood Brain Barrier ◽  
Cell Junctions ◽  
Brain Barrier ◽  
Brain Endothelial Cell ◽  
Blood Brain ◽  
Cell Cell

Association between Serum Carcinoembryonic Antigen and Endothelial Cell Adhesion Molecules in Colorectal Cancer

Oncology ◽  
2003 ◽  
Vol 65 (2) ◽  
pp. 132-138 ◽  
Author(s):  
Mario Roselli ◽  
Fiorella Guadagni ◽  
Francesca Martini ◽  
Antonella Spila ◽  
Sabrina Mariotti ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Adhesion ◽  
Endothelial Cell ◽  
Carcinoembryonic Antigen ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Serum Carcinoembryonic Antigen ◽  
Endothelial Cell Adhesion Molecules ◽  
Endothelial Cell Adhesion
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