Poly (Vinyl Alcohol) Beads with Core-Shell Structure for Drug Delivery

Author(s):  
Cherng-Ju Kim ◽  
Ping I. Lee
Nano Letters ◽  
2012 ◽  
Vol 12 (11) ◽  
pp. 5840-5844 ◽  
Author(s):  
Dali Shao ◽  
Hongtao Sun ◽  
Mingpeng Yu ◽  
Jie Lian ◽  
Shayla Sawyer

2006 ◽  
Vol 243 (1) ◽  
pp. 190-199 ◽  
Author(s):  
Luciana S. Peixoto ◽  
Fabricio M. Silva ◽  
Mariana A. L. Niemeyer ◽  
Gaudencio Espinosa ◽  
Príamo A. Melo ◽  
...  

NANO ◽  
2014 ◽  
Vol 09 (04) ◽  
pp. 1450042 ◽  
Author(s):  
CONG-WANG ZHANG ◽  
CHANG-CHUN ZENG ◽  
YING XU

Fe 3 O 4– SiO 2 core–shell structure nanoparticles containing magnetic properties were investigated for their potential use in drug delivery. The Fe 3 O 4– SiO 2 core–shell structure nanoparticles were successfully synthesized by a simple and convenient way. The Fe 3 O 4– SiO 2 nanoparticles showed superparamagnetic behavior, indicating a great application potential in separation technologies. From the application point of view, the prepared nanoparticles were found to act as an efficient drug carrier. Specifically, the surface of the core–shell nanoparticles was modified with amino groups by use of silane coupling agent 3-aminopropyltriethoxysilane (APTS). Doxorubicin (DOX) was successfully grafted to the surface of the core–shell nanoparticles after the decoration with the carboxyl acid groups on the surface of amino-modified core–shell structure nanoparticles. Moreover, the nanocomposite showed a good drug delivery performance in the DOX-loading efficiency and drug release experiments, confirming that the materials had a great application potential in drug delivery. It is envisioned that the prepared materials are the ideal agent for application in medical diagnosis and therapy.


Author(s):  
Meera Moydeen Abdul Hameed ◽  
Syed Ali Padusha Mohamed Khan ◽  
Badr M. Thamer ◽  
Abdullah Al-Enizi ◽  
Ali Aldalbahi ◽  
...  

2012 ◽  
Vol 21 (4) ◽  
pp. 346-348 ◽  
Author(s):  
Xupin Zhuang ◽  
Lei Shi ◽  
Bo Zhang ◽  
Bowen Cheng ◽  
Weimin Kang

Gels ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 228
Author(s):  
Tisana Kaewruethai ◽  
Chavee Laomeephol ◽  
Yue Pan ◽  
Jittima Amie Luckanagul

Currently, research in nanoparticles as a drug delivery system has broadened to include their use as a delivery system for bioactive substances and a diagnostic or theranostic system. Nanogels, nanoparticles containing a high amount of water, have gained attention due to their advantages of colloidal stability, core-shell structure, and adjustable structural components. These advantages provide the potential to design and fabricate multifunctional nanosystems for various biomedical applications. Modified or functionalized polymers and some metals are components that markedly enhance the features of the nanogels, such as tunable amphiphilicity, biocompatibility, stimuli-responsiveness, or sensing moieties, leading to specificity, stability, and tracking abilities. Here, we review the diverse designs of core-shell structure nanogels along with studies on the fabrication and demonstration of the responsiveness of nanogels to different stimuli, temperature, pH, reductive environment, or radiation. Furthermore, additional biomedical applications are presented to illustrate the versatility of the nanogels.


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