Glycoconjugates and Nuclear Membrane Lectin from Rat Brain Cell Nuclei

1997 ◽  
pp. 909-912
Author(s):  
N. G. Aleksidze ◽  
R. G. Akhalkatsi ◽  
T. Bolotashvili
Keyword(s):  
Rat Brain ◽  
Nuclear Membrane ◽  
Brain Cell ◽  
Cell Nuclei

ALUMINUM NEUROTOXICITY IN THE RAT BRAIN

1992 ◽  
Vol 02 (04) ◽  
pp. 493-504 ◽  
Author(s):  
S. YUMOTO ◽  
H. OHASHI ◽  
H. NAGAI ◽  
S. KAKIMI ◽  
Y. OGAWA ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Rat Brain ◽  
Morphological Changes ◽  
Brain Cell ◽  
Nerve Cells ◽  
Cell Nuclei ◽  
Pixe Analysis ◽  
Aluminum Neurotoxicity ◽  
The Brain

To investigate the etiology of Alzheimer’s disease, we administered aluminum to healthy rats and examined the aluminum uptake in the brain and isolated brain cell nuclei by particle-induced X-ray emission (PIXE) analysis. Ten days after the last injection, Al was detected in the rat brain and in isolated brain cell nuclei by PIXE analysis. Al was also demonstrated in the brain after 15 months of oral aluminum administration. Moreover, Al was detected in the brain and isolated brain cell nuclei from the patients with Alzheimer’s disease. Silver impregnation studies revealed that spines attached to the dendritic processes of cortical nerve cells decreased remarkably after aluminum administration. Electron microscopy revealed characteristic inclusion bodies in the hippocampal nerve cells 75 days after the injection. These morphological changes in the rat brain after the aluminum administration were similar to those reportedly observed in the brain of Alzheimer’s disease patients. Our results indicate that Alzheimer’s disease is caused by irreversible accumulation of aluminum in the brain, as well as in the nuclei of brain cells.

Poly(ADP-ribosyl)ation enhancement in brain cell nuclei is associated with diabetic neuropathy

2004 ◽  
Vol 18 (4) ◽  
pp. 198-204 ◽  
Author(s):  
Tamara Kuchmerovska ◽  
Ihor Shymanskyy ◽  
Georgiy Donchenko ◽  
Mykola Kuchmerovskyy ◽  
Larysa Pakirbaieva ◽  
...  
Keyword(s):  
Diabetic Neuropathy ◽  
Brain Cell ◽  
Cell Nuclei

Staining Differences in Cell Nuclei

1955 ◽  
Vol s3-96 (34) ◽  
pp. 227-237
Author(s):  
LUCIEN LISON
Keyword(s):  
Nuclear Membrane ◽  
Low Permeability ◽  
Microscopical Observation ◽  
Cell Nuclei ◽  
Intact Nucleus ◽  
Calculated Probability ◽  
Fixed State ◽  
Parenchymal Cells ◽  
Made In

If the parenchymal cells of the liver of the rat, or certain other cells, are stained with a modified Mallory stain or with iron haematoxylin, the nuclei are stained in two different ways. This effect may be observed after various fixatives. Direct microscopical observation shows that when part of a nucleus is cut away by the microtome-knife, the part of it remaining in the section stains differently from an intact nucleus. The probability of a nucleus being wholly or only partly contained in a section of a particular thickness can be calculated. Counts made in sections of various thicknesses show that the proportion of nuclei stained in the different ways is consistent with the calculated probability. It is suggested that the nuclear membrane in the fixed state presents a relatively low permeability.

Acute and long-term effects of VX in rat brain cell aggregate culture

2021 ◽  
pp. 105256
Author(s):  
Thomas W. Sawyer ◽  
Yushan Wang ◽  
Mercy Villanueva ◽  
Yanfeng Song ◽  
Grant Hennes
Keyword(s):  
Rat Brain ◽  
Brain Cell ◽  
Cell Aggregate ◽  
Long Term Effects ◽  
Aggregate Culture
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