Dual Role of Transport Competition in Amino Acid Deprivation of the Central Nervous System by Hyperphenylalaninemia

1988 ◽  
pp. 68-78
Author(s):  
Halvor N. Christensen ◽  
Carlos de Céspedes
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Amino Acid ◽  
Dual Role ◽  
Amino Acid Deprivation ◽  
The Central Nervous System

scholarly journals Role of VP2 amino acid 141 in tropism of Theiler's virus within the central nervous system.

1996 ◽  
Vol 70 (11) ◽  
pp. 8213-8217 ◽  
Author(s):  
N Jarousse ◽  
C Martinat ◽  
S Syan ◽  
M Brahic ◽  
A McAllister
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Amino Acid ◽  
Theiler's Virus ◽  
The Central Nervous System

A possible dual role of noradrenaline in cardiovascular responses mediated by the central nervous system

1968 ◽  
Vol 46 (4) ◽  
pp. 595-599 ◽  
Author(s):  
D. J. Gagnon ◽  
K. I. Melville
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Artificial Respiration ◽  
Cardiovascular Responses ◽  
Dual Role ◽  
Neuronal Uptake ◽  
Reversal Phenomenon ◽  
The Central Nervous System ◽  
Uptake Of Noradrenaline

The cardiovascular responses induced by intraventricular noradrenaline after intraventricular pretreatment with reserpine, imipramine, and chlorpromazine were studied in cats anesthetized with chloralose and under artificial respiration. Pretreatment with all three agents produced various degrees of "reversal" of the usual cardiovascular depressant responses to noradrenaline (50 μg intraventricularly), leading to significant pressor responses and tachycardia. These sympathetic excitatory cardiovascular responses were significantly reduced by spinal C-2 section. It is suggested that this reversal phenomenon is not due entirely to brain noradrenaline depletion, but that all three agents (reserpine, imipramine, and chlorpromazine) act by blocking neuronal uptake of noradrenaline, thereby preventing the usual central cardiovascular inhibitory effects of the amine. These findings also suggest a possible dual role of noradrenaline in cardiovascular changes mediated by the central nervous system.

scholarly journals l-Serine in disease and development

2003 ◽  
Vol 371 (3) ◽  
pp. 653-661 ◽  
Author(s):  
Tom J. de KONING ◽  
Keith SNELL ◽  
Marinus DURAN ◽  
Ruud BERGER ◽  
Bwee-Tien POLL-THE ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Amino Acid ◽  
Cellular Proliferation ◽  
De Novo ◽  
Essential Amino Acids ◽  
Purine Nucleotides ◽  
The Central Nervous System ◽  
And Function

The amino acid l-serine, one of the so-called non-essential amino acids, plays a central role in cellular proliferation. l-Serine is the predominant source of one-carbon groups for the de novo synthesis of purine nucleotides and deoxythymidine monophosphate. It has long been recognized that, in cell cultures, l-serine is a conditional essential amino acid, because it cannot be synthesized in sufficient quantities to meet the cellular demands for its utilization. In recent years, l-serine and the products of its metabolism have been recognized not only to be essential for cell proliferation, but also to be necessary for specific functions in the central nervous system. The findings of altered levels of serine and glycine in patients with psychiatric disorders and the severe neurological abnormalities in patients with defects of l-serine synthesis underscore the importance of l-serine in brain development and function. This paper reviews these recent insights into the role of l-serine and the pathways of l-serine utilization in disease and during development, in particular of the central nervous system.

Role of a nurse in the rehabilitation of children using ReviMotion hardware and software complex

2020 ◽  
pp. 49-56
Author(s):  
T. Shirshova
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
School Age Children ◽  
Equipment Management ◽  
School Age ◽  
Rehabilitation Process ◽  
Software Complex ◽  
Trained Personnel ◽  
The Central Nervous System

Disorders of the musculoskeletal system in school-age children occupy 1-2 places in the structure of functional abnormalities. Cognitive impairment without organic damage to the central nervous system is detected in 30-56% of healthy school children. Along with the increase in the incidence rate, the demand for rehabilitation systems, which allow patients to return to normal life as soon as possible and maintain the motivation for the rehabilitation process, is also growing. Adaptation of rehabilitation techniques, ease of equipment management, availability of specially trained personnel and availability of technical support for complexes becomes important.

The Role of Neuropeptide Y and Peptide YY in the Development of Obesity via Gut-brain Axis

2019 ◽  
Vol 20 (7) ◽  
pp. 750-758 ◽  
Author(s):  
Yi Wu ◽  
Hengxun He ◽  
Zhibin Cheng ◽  
Yueyu Bai ◽  
Xi Ma
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuropeptide Y ◽  
Metabolic Diseases ◽  
Peptide Yy ◽  
Vital Role ◽  
Gut Peptides ◽  
Nonalcoholic Fatty Liver ◽  
The Central Nervous System

Obesity is one of the main challenges of public health in the 21st century. Obesity can induce a series of chronic metabolic diseases, such as diabetes, dyslipidemia, hypertension and nonalcoholic fatty liver, which seriously affect human health. Gut-brain axis, the two-direction pathway formed between enteric nervous system and central nervous system, plays a vital role in the occurrence and development of obesity. Gastrointestinal signals are projected through the gut-brain axis to nervous system, and respond to various gastrointestinal stimulation. The central nervous system regulates visceral activity through the gut-brain axis. Brain-gut peptides have important regulatory roles in the gut-brain axis. The brain-gut peptides of the gastrointestinal system and the nervous system regulate the gastrointestinal movement, feeling, secretion, absorption and other complex functions through endocrine, neurosecretion and paracrine to secrete peptides. Both neuropeptide Y and peptide YY belong to the pancreatic polypeptide family and are important brain-gut peptides. Neuropeptide Y and peptide YY have functions that are closely related to appetite regulation and obesity formation. This review describes the role of the gutbrain axis in regulating appetite and maintaining energy balance, and the functions of brain-gut peptides neuropeptide Y and peptide YY in obesity. The relationship between NPY and PYY and the interaction between the NPY-PYY signaling with the gut microbiota are also described in this review.

Sign in / Sign up

Export Citation Format

Share Document