Intra-Mammary Steroid Transformation: Implications for Tumorigenesis and Natural Progression

1989 ◽  
pp. 185-199
Author(s):  
W. R. Miller
Keyword(s):  
Steroid Transformation ◽  
Natural Progression

scholarly journals Remote patient monitoring for ED discharges in the COVID-19 pandemic

2021 ◽  
Vol 38 (3) ◽  
pp. 229-231
Author(s):  
Ahmad A Aalam ◽  
Colton Hood ◽  
Crystal Donelan ◽  
Adam Rutenberg ◽  
Erin M Kane ◽  
...  
Keyword(s):  
Patient Monitoring ◽  
Clinical Status ◽  
Remote Patient Monitoring ◽  
Hospital Capacity ◽  
Vulnerable Patients ◽  
Natural Progression ◽  
Extended Access ◽  
Discharged Patients ◽  
The Individual ◽  
Remote Patient

COVID-19 has had a significant effect on healthcare resources worldwide, with our knowledge of the natural progression of the disease evolving for the individual patient. To allow for early detection of worsening clinical status, protect hospital capacity and provide extended access for vulnerable patients, our emergency department developed a remote patient monitoring programme for discharged patients with COVID-19. The programme uses a daily emailed secure link to a survey in which patients submit biometric and symptoms data for monitoring. Patients’ meeting criteria are escalated to a physician for a phone or video visit. Here, we describe the development, implementation and preliminary analysis of utilisation of the programme.

scholarly journals Natural Progression of Non-Alcoholic Steatohepatitis to Hepatocellular Carcinoma

Biomedicines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 184
Author(s):  
Daryl Ramai ◽  
Waqqas Tai ◽  
Michelle Rivera ◽  
Antonio Facciorusso ◽  
Nicola Tartaglia ◽  
...  
Keyword(s):  
Public Health ◽  
Hepatocellular Carcinoma ◽  
Lipid Peroxidation ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Steatohepatitis ◽  
Natural Progression ◽  
Public Health Threat ◽  
Alcoholic Fatty Liver Disease

Non-alcoholic steatohepatitis (NASH) is a chronic and progressive form of non-alcoholic fatty liver disease (NAFLD). Its global incidence is increasing which makes NASH an epidemic and a public health threat. Due to repeated insults to the liver, patients are at risk for developing hepatocellular carcinoma (HCC). The progression of NASH to HCC was initially defined according to a two-hit model which involved the development of steatosis, followed by lipid peroxidation and inflammation. However, current research defines a “multi-hit” or “multi-parallel hit” model which synthesizes several contributing pathways involved in progressive fibrosis and oncogenesis. This perspective considers the effects of cellular, genetic, immunologic, metabolic, and endocrine pathways leading up to HCC which underscores the complexity of this condition. This article will provide an updated review of the pathogenic mechanisms leading from NASH to HCC as well as an exploration of the role of biomarkers and screening.

scholarly journals Natural Progression of Low-Gradient Severe Aortic Stenosis with Preserved Ejection Fraction

2014 ◽  
Vol 41 (3) ◽  
pp. 273-279 ◽  
Author(s):  
Antony Leslie Innasimuthu ◽  
Sanjay Kumar ◽  
Jason Lazar ◽  
William E. Katz
Keyword(s):  
Aortic Stenosis ◽  
Ejection Fraction ◽  
Severe Aortic Stenosis ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Aortic Valve Area ◽  
Ventricular Ejection Fraction ◽  
Mild Stenosis ◽  
Natural Progression

Because the natural progression of low-gradient aortic stenosis (LGAS) has not been well defined, we performed a retrospective study of 116 consecutive patients with aortic stenosis who had undergone follow-up echocardiography at a median interval of 698 days (range, 371–1,020 d). All patients had preserved left ventricular ejection fraction (>0.50) during and after follow-up. At baseline, patients were classified by aortic valve area (AVA) as having mild stenosis (≥1.5 cm2), moderate stenosis (≥1 to <1.5 cm2), or severe stenosis (<1 cm2). Severe aortic stenosis was further classified by mean gradient (LGAS, mean <40 mmHg; high-gradient aortic stenosis [HGAS], mean ≥40 mmHg). We compared baseline and follow-up values among 4 groups: patients with mild stenosis, moderate stenosis, LGAS, and HGAS. At baseline, 30 patients had mild stenosis, 54 had moderate stenosis, 24 had LGAS, and 8 had HGAS. Compared with the moderate group, the LGAS group had lower AVA but similar mean gradient. Yet the actuarial curves for progressing to HGAS were significantly different: 25% of patients in LGAS reached HGAS status significantly earlier than did 25% of patients in the moderate-AS group (713 vs 881 d; P=0.035). Because LGAS has a high propensity to progress to HGAS, we propose that low-gradient aortic stenosis patients be closely monitored as a distinct subgroup that warrants more frequent echocardiographic follow-up.

Natural Progression of Recovery from Concussion in a Pediatric Population

2018 ◽  
Vol 99 (11) ◽  
pp. e142
Author(s):  
Andrée-Anne Ledoux ◽  
Gerard Gioia ◽  
Isabelle Gagnon ◽  
Jocelyn Gravel ◽  
Kathy Boutis ◽  
...  
Keyword(s):  
Pediatric Population ◽  
Natural Progression

scholarly journals Natural progression of premature pubarche and underlying diseases

2018 ◽  
Vol 89 (4) ◽  
pp. 238-245
Author(s):  
María Luisa Sancho Rodríguez ◽  
Gloria Bueno Lozano ◽  
José Ignacio Labarta Aizpún ◽  
Antonio de Arriba Muñoz
Keyword(s):  
Natural Progression ◽  
Underlying Diseases ◽  
Premature Pubarche

scholarly journals Faeth fiadha. "Lorica" świętego Patryka

Vox Patrum ◽  
2004 ◽  
Vol 46 ◽  
pp. 547-559
Author(s):  
Ryszarda Bulas
Keyword(s):  
The Third ◽  
Natural Progression ◽  
The World

The article treats of the most famous sort of Irish protective prayer, which name is lorica (breastplate). The author talks over this kind of prayer and inserts its translation. Next, on the base of article of O'Donoghue, the author analyzes every stanza of S. Patrick's lorica. First and eight stanza tells about Trinity and God, in the second and second the power of Christ is invoked in all its main manifestations: his birth, his baptism, his death and burial, his resurrection and his coming in judgment. The third stanza descends from the sphere of deity to the world of the first creation - angels. The fourth stanza dips down from heavenly host to the visible cosmos in its spheres and elements: sun, moon, and firmament, and the four elements: fire, air, water and earth. In the fifth stanza we are back at the source of creation, a natural progression from the invocation of created nature in the fourth stanza. The sixth stanza tells about spells cast by women and blacksmiths and druids.

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