High-Risk Profile

1988 ◽  
pp. 185-231
Author(s):  
Ian E. Wickramasekera
Keyword(s):  
High Risk ◽  
Risk Profile

scholarly journals A Peri-Implant Disease Risk Score for Patients with Dental Implants: Validation and the Influence of the Interval between Maintenance Appointments

2019 ◽  
Vol 8 (2) ◽  
pp. 252 ◽  
Author(s):  
Miguel de Araújo Nobre ◽  
Francisco Salvado ◽  
Paulo Nogueira ◽  
Evangelista Rocha ◽  
Peter Ilg ◽  
...  
Keyword(s):  
High Risk ◽  
Risk Score ◽  
Disease Risk ◽  
Disease Incidence ◽  
Risk Groups ◽  
Risk Profile ◽  
Moderate Risk ◽  
C Statistic ◽  
Disease Risk Score ◽  
Very High

Background: There is a need for tools that provide prediction of peri-implant disease. The purpose of this study was to validate a risk score for peri-implant disease and to assess the influence of the recall regimen in disease incidence based on a five-year retrospective cohort. Methods: Three hundred and fifty-three patients with 1238 implants were observed. A risk score was calculated from eight predictors and risk groups were established. Relative risk (RR) was estimated using logistic regression, and the c-statistic was calculated. The effect/impact of the recall regimen (≤ six months; > six months) on the incidence of peri-implant disease was evaluated for a subset of cases and matched controls. The RR and the proportional attributable risk (PAR) were estimated. Results: At baseline, patients fell into the following risk profiles: low-risk (n = 102, 28.9%), moderate-risk (n = 68, 19.3%), high-risk (n = 77, 21.8%), and very high-risk (n = 106, 30%). The incidence of peri-implant disease over five years was 24.1% (n = 85 patients). The RR for the risk groups was 5.52 (c-statistic = 0.858). The RR for a longer recall regimen was 1.06, corresponding to a PAR of 5.87%. Conclusions: The risk score for estimating peri-implant disease was validated and showed very good performance. Maintenance appointments of < six months or > six months did not influence the incidence of peri-implant disease when considering the matching of cases and controls by risk profile.

PP-042 THE EVALUATION OF STREPTOKINAZ REZISTANCE, A FIBRINOLYTIC AGENT IN HIGH RISK PROFILE FOR CORONARY ARTERY DISEASE LIVING UPPER FIRAT REGION

2010 ◽  
Vol 140 ◽  
pp. S54
Author(s):  
Musa Bulut ◽  
Adil Baydas ◽  
Mehmet Ali Kobat ◽  
Mustafa Yavuzkir ◽  
Necati Dagli ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
High Risk ◽  
Risk Profile ◽  
Fibrinolytic Agent ◽  
Artery Disease

scholarly journals Determining the Spatial and Risk Heterogeneity in HIV Prevalence among IDUs in India: Analysis Based on the Data from Integrated Biological and Behavioural Surveillance (IBBS), 2014-15

2020 ◽  
Author(s):  
Santhakumar Aridoss ◽  
Joseph David ◽  
Nagaraj Jaganathasamy ◽  
Malathi Mathiyazhakan ◽  
Ganesh Balasubramanian ◽  
...  
Keyword(s):  
High Risk ◽  
Positive Impact ◽  
Risk Profile ◽  
Hiv Prevalence ◽  
Fine Tuning ◽  
Prevention Measures ◽  
Inconsistent Condom ◽  
Cross Sectional ◽  
Indian States ◽  
Behavioural Surveillance

Abstract Background: Spatial and risk-related heterogeneity among high-risk HIV populations marks the prevalence, dynamics, and management of HIV. Identifying the spatial heterogeneity of disease prevalence and risk heterogeneity at a specific location is crucial for fine-tuning the strategic interventions. On this background, we analysed the behavioural data and HIV prevalence of IDUs, in a state-specific manner. Objectives: To structure the IDU population based on their risk of infection and location, and to determine the HIV prevalence for each of the IDU subpopulation based on their spatial distribution and risk profile. Methods: We analysed the behavioural data and HIV prevalence obtained from the National Integrated Biological and Behavioural Surveillance (IBBS), a nationwide cross-sectional community-based study conducted in 2014-2015. We included the data obtained from 19,902 IDUs across 53 domains in 29 states of India for analysis. We grouped the IDUs into different categories, based on their risk profile, and analysed the corresponding HIV prevalence among IDUs in each category for all states. Results: State-specific analysis of HIV prevalence among the IDUs exhibiting safe and high-risk characteristics revealed that the HIV prevalence was the highest in Uttar Pradesh irrespective of the risk-structure of the state. HIV infection was highly prevalent in the Central and most Northern states, and in a few East and North-Eastern Indian states. HIV Prevalence was predominantly higher among those IDUs self-reporting presence of at least one STI symptom, following unsafe injecting practices, IDUs with inconsistent condom usage with sexual partners (other than regular partners), and those with inadequate knowledge of HIV /AIDS. Conclusion: Stratified, region-specific interventions based on geographic risk-structure and combination-approaches are recommended to prevent HIV transmission among IDUs. Implementing measures to generate adequate awareness of STI, HIV, and injecting behaviours, specifically among IDUs in the Central and Northern states of India and advocating safe sexual practises among all IDUS will have a positive impact on HIV prevention measures among IDUs.

Abstract 19639: Infective Endocarditis Following Transcatheter Valve Implantation: A Systematic Review

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Ignacio J Amat-Santos ◽  
Henrique B Ribeiro ◽  
Marina Urena ◽  
Ricardo Allende ◽  
Cristine Houde ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
High Risk ◽  
Hospital Mortality ◽  
Risk Profile ◽  
Electronic Search ◽  
Transcatheter Valve ◽  
Few Data ◽  
Valve Implantation ◽  
Transcatheter Valves ◽  
Very High

Objectives: To describe the incidence, features, predisposing factors and outcomes of infective endocarditis (IE) following transcatheter valve implantation (TVI). Background: Very few data exist on IE following TVI. Methods: Studies published between 2000 and 2013 regarding IE in patients with aortic (TAVI) or pulmonary (TPVI) transcatheter valves were identified through systematic electronic search. Result: A total of 28 publications describing 60 patients (32 TAVI, 28 TPVI) were identified. Most TAVI patients (66% males, 80±7 years) had a very high-risk profile (LogEuroSCORE: 30.4±14.0%, p<0.001 compared to previous TAVI registries). In TPVI patients (90% males, 19±6 years), IE was more frequent in stenotic conduit/valve (61%) (p <0.001 vs. previous TPVI series). Median time between TVI and IE was 5.5 (2-12) months. Typical microorganisms were mostly found with a higher incidence of enterococci after TAVI (34.4% vs. 0%, p =0.009), and S.aureus after TPVI (29.4% vs. 6.2%, p =0.041). Up to 60% of the TAVI-IE patients were managed medically despite related complications such as local extension, embolism and/or heart failure in >50% of patients. Valve explantation rate was 57% and 23% in balloon- and self-expandable valves, respectively (p=0.07). In-hospital mortality for TAVI-IE was 34.4%. Most TPVI-IE patients (75%) were managed surgically, and in-hospital mortality was 7.1%. Conclusions: Most cases of IE post-TVI were males, with a very high-risk profile (TAVI) or underlying stenotic conduit/valve (TPVI). Typical -but different- microorganisms of IE were involved in half of the TAVI and TPVI cases. Most TPVI-IE patients were managed surgically as opposed to TAVI patients, and mortality rate was high in both cohorts.

Benefit-risk profile of extended dual antiplatelet therapy beyond 1 year in patients with high risk of ischemic or bleeding events after PCI

Platelets ◽  
2020 ◽  
pp. 1-9
Author(s):  
Hao-Yu Wang ◽  
Run-Lin Gao ◽  
Bo Xu ◽  
Yue-Jin Yang ◽  
Dong Yin ◽  
...  
Keyword(s):  
High Risk ◽  
Antiplatelet Therapy ◽  
Dual Antiplatelet Therapy ◽  
Risk Profile ◽  
Bleeding Events

scholarly journals A tax compliance risk profile of guesthouse owners in Soweto, South Africa

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Marina Bornman ◽  
Pusheletso Ramutumbu
Keyword(s):  
South Africa ◽  
High Risk ◽  
Small Business ◽  
Tax Compliance ◽  
Business Owners ◽  
Risk Profile ◽  
Research Approach ◽  
Small Business Owners ◽  
Guest House ◽  
Compliance Behaviour

Background: A conceptual framework to assess the particular tax situation of small business owners identifies three key aspects that distinguish small business owners’ perceptions of their tax obligation. These aspects are: they are likely to perceive more opportunities not to comply than employed taxpayers; they are likely to lack meaningful taxation knowledge and they are likely to frame the paying of taxes as a loss.Aim: The aim of this article was to sketch a tax compliance risk profile of guest house owners in Soweto to suggest strategies to negate those factors that may negatively influence their compliance behaviour.Setting: Tax compliance is a priority for tax administrations, especially in developing countries such as South Africa where small businesses are a high compliance risk group. Small guest houses’ income is usually variable and/or cash-based and not easily verifiable against third-party data, which creates a high risk of non-compliance.Methods: A mixed methods research approach was followed. Empirical evidence in the form of semi-structured questionnaires administered face-to-face with 23 guest house owners in Soweto was statistically and thematically analysed to compile a profile of the tax compliance risk according to the framework for tax compliance behaviour of small business owners.Results: Factors such as age, gender and tax morale show favourable results for tax compliant behaviour. However, perceptions of fairness, perceived opportunity for non-compliance, knowledge deficits, decision frames, industry, business size and social norms embrace a high risk of non-compliance for this population.Conclusion: Information pointing out the factors that could negatively influence tax compliance behaviour in this population was obtained. Strategies for empowering small business owners to comply voluntarily with their tax obligations are suggested and include, for example, taxpayer education and improved communication efforts from the revenue authority.

scholarly journals A risk profile for identifying community-dwelling elderly with a high risk of recurrent falling: results of a 3-year prospective study

2006 ◽  
Vol 17 (3) ◽  
pp. 417-425 ◽  
Author(s):  
S. M. F. Pluijm ◽  
J. H. Smit ◽  
E. A. M. Tromp ◽  
V. S. Stel ◽  
D. J. H. Deeg ◽  
...  
Keyword(s):  
High Risk ◽  
Prospective Study ◽  
Risk Profile ◽  
Community Dwelling

Investigation of gastrointestinal stromal tumor (GIST) care management in GIST patients (pts) receiving short-term versus long-term imatinib (IM) adjuvant therapy: A chart review analysis.

2012 ◽  
Vol 30 (34_suppl) ◽  
pp. 195-195
Author(s):  
Anthony Paul Conley ◽  
Annie Guérin ◽  
Medha Sasane ◽  
Geneviève Gauthier ◽  
Frances Schwiep ◽  
...  
Keyword(s):  
Risk Assessment ◽  
High Risk ◽  
Risk Profile ◽  
Prescribing Patterns ◽  
Community Practice ◽  
Short Term ◽  
Online Data ◽  
Kit Mutation ◽  
Nccn Guidelines

195 Background: Although optimal duration of adjuvant IM therapy in Kit+ GIST pts is unknown, the NCCN guidelines recommend treatment for ≥36 months in high-risk pts based on clinical trials showing reduced risk of recurrence and mortality in pts receiving long-term adjuvant IM. The objective of this study was to investigate clinicians’ recurrence risk assessment and GIST management in patients receiving adjuvant IM for short- (6-12 months) vs. long-term (≥24 months) in community practice. Methods: GIST-related and treatment characteristic information on adult pts with primary resectable Kit+ GIST initiating IM ≤84 days after surgery (short-term: 411 pts; long-term: 408 pts) was collected from 320 U.S. oncologists using an online data collection form. In addition, physician prescribing patterns and perception of risk assessment and IM duration were collected. Results: Indicators of risk (tumor size, mitotic count, and tumor location) were significantly associated with IM treatment duration. Tumor rupture status did not impact IM duration, except when unknown, in which case pts had longer IM duration. About 50% of pts had not been tested for Kit mutation; 31% of physicians reported that it would not have changed therapy/management or were not aware of how results should have impacted GIST management. Among short-term pts for whom physicians reported a reason for IM discontinuation, main reasons included non-severe adverse events, completion of the 1-year treatment scheduled, economic constraint/health plan coverage change, and pts’ preference. Overall, 77.8% of surveyed physicians reported that pt risk profile drove their decision of continuing IM over an extended period of time. However, in practice 39.9% of the short-term pts and 48.8% of the long-term pts had a high risk profile as assessed by Fletcher classification; suggesting a lack of consistency between treatment related opinions and practice. Conclusions: These observed discrepancies highlight the need for standardization of risk assessment practices and education among community oncologists and pts.

A Highly Bioavailable Omega-3 Free Fatty Acid Formulation Improves the Cardiovascular Risk Profile in High-Risk, Statin-Treated Patients With Residual Hypertriglyceridemia (the ESPRIT Trial)

2013 ◽  
Vol 35 (9) ◽  
pp. 1400-1411.e3 ◽  
Author(s):  
Kevin C. Maki ◽  
David G. Orloff ◽  
Stephen J. Nicholls ◽  
Richard L. Dunbar ◽  
Eli M. Roth ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
High Risk ◽  
Risk Profile ◽  
Cardiovascular Risk Profile ◽  
Omega 3 ◽  
Acid Formulation
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