Posttraumatic Stress, Generalized Anxiety, and Obsessive-Compulsive Disorders

1991 ◽  
pp. 141-165
Author(s):  
Ronald A. Kleinknecht
Author(s):  
Philip Cowen ◽  
Paul Harrison ◽  
Tom Burns

Chapter 9 discusses how the symptom of anxiety is found in many disorders. In the anxiety disorders, it is the most severe and prominent symptom, and it is also prominent in the obsessional disorders, although these are characterizedby their striking obsessional symptoms. In DSM-IV, obsessive–compulsive disorder is classifi ed as a type of anxiety disorder, but in ICD-10 it is classified separately. We have followed the DSM convention and included obsessional disorders in this chapter, as well as covering generalized anxiety disorder (GAD), phobias, panic, mixed anxiety and depression, transcultural variations, and obsessive-compulsive disorder (OCD).


1993 ◽  
Vol 34 (4) ◽  
pp. 243-248 ◽  
Author(s):  
Matig R. Mavissakalian ◽  
Mary Sue Hamann ◽  
Said Abou Haidar ◽  
Christopher M. de Groot

2020 ◽  
Vol 8 (B) ◽  
pp. 20-25
Author(s):  
Sayed Tantawy ◽  
Nada Ikram Karamat ◽  
Rana Sulaiman Al Gannas ◽  
Sara Abdulrahman Khadem ◽  
Dalia M. Kamel

BACKGROUND: Mood disorders such as generalized anxiety disorder (GAD), obsessive-compulsive disorders, and other mental disorders could be due to obesity which is a prevalent condition among majority of population nowadays, whereas changes in anxiety level of individuals are also thought to have an influence on body mass index (BMI). AIM: The objective of the study was to investigate the relationship between BMI and anxiety status among Ahlia University students. METHODS: A total of 80 male and female students from different colleges of Ahlia University were included in our study. Their ages ranged between 18 and 25 years old with different BMI. The students were asked to fill a (GAD 7 scale) questionnaire related to anxiety level; their BMI was calculated. RESULTS: There was a significant relationship between BMI and anxiety status (negative correlation) (p < 0.019). CONCLUSIONS: We concluded that BMI is inversely proportional to anxiety level, the reduction in BMI level is linked with elevated anxiety level and vice versa.


2019 ◽  
Author(s):  
German I. Todorov ◽  
Karthikeyan Mayilvahanan ◽  
David Ashurov ◽  
Catarina Cunha

Autism Spectrum Disorder (ASD) is a pervasive developmental disorder, that is raising at a concerning rate. However, underlying mechanisms are still to be discovered. Obsessions and compulsions are the most debilitating aspect of these disorders (OCD), and they are the treatment priority for patients. SAPAP3 knock out mice present a reliable mouse model for repetitive compulsive behavior and are mechanistically closely related to the ASD mouse model Shank3 on a molecular level and AMPA receptor net effect. The phenotype of SAPAP3 knock out mice is obsessive grooming that leads to self-inflicted lesions by 4 months of age. Recent studies have accumulated evidence, that epigenetic mechanisms are important effectors in psychiatric conditions such as ASD and OCD. Methylation is the most studied mechanism, that recently lead to drug developments for more precise cancer treatments. We injected SAPAP3 mice with an epigenetic demethylation drug RG108 during pregnancy and delayed the onset of the phenotype in the offspring by 4 months. This result gives us clues about possible mechanism involved in OCD and ASD. Additionally, it shows that modulation of methylation mechanisms during development might be explored as a preventative treatment in the cases of high inherited risk of certain mental health conditions.


2016 ◽  
Vol 4 (2) ◽  
pp. 103-111
Author(s):  
María Yoldi-Negrete ◽  
Mónica Flores-Ramos ◽  
Alejandra Montserrat Rodríguez-Ramírez ◽  
Carvajal-Lohr Armando ◽  
Jorge Ávila-Solorio ◽  
...  

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