Clinical Correlation

2008 ◽  
pp. 167-171
Author(s):  
Gregory Cooper ◽  
Gerald Eichhorn ◽  
Robert Rodnitzky
Keyword(s):  

Purpose: This case discusses the neurological impact of Wallenberg syndrome on the visual-vestibular system and provides a clinical pathologic correlation between neuro-anatomic involvements with the manifesting symptoms. Case Report: A 50-year-old male presented for consultation following a left lateral medullary infarct occlusion of the left vertebral artery (Wallenberg syndrome) with complaints of intermittent binocular diplopia, vertigo, and oscillopsia. Assessment revealed an intermittent central nystagmus, a right skew deviation, and a left Horner’s syndrome. Video recordings of the nystagmus and ocular motor responses were documented. Conclusion: Wallenberg syndrome has very defined characteristics which can be used clinically to make a definitive diagnosis.It is important for eye care professionals to understand the neuro-anatomic involvements associated with this condition and make the clinical correlation to aid in the treatment and management of these patients.


2016 ◽  
Vol 4 (6) ◽  
pp. 2282-2287
Author(s):  
Dr. Anuradha Salvi ◽  
DrLata Ratnoo ◽  
Dr. Seema Meena ◽  
Dr. Sonia Saini ◽  
Dr. Priyanka Baghotia ◽  
...  

2020 ◽  
Vol 15 (2) ◽  
pp. 156-159 ◽  
Author(s):  
Deborah L. Sanchez ◽  
Adam J. Fusick ◽  
Steven R. Gunther ◽  
Michael J. Hernandez ◽  
Gregory A. Sullivan ◽  
...  

Background: Lamotrigine is a phenyltriazine medication that has been approved by the United States Food and Drug Administration as monotherapy and as an adjunctive agent for the treatment of seizure disorder. It was later approved by the FDA for the treatment of bipolar disorder. Lamotrigine is generally well tolerated by patients, but some serious symptoms can occur during treatment. These severe side effects include rashes and multi-organ failure. Lamotrigine has also been associated with the development of mental status changes, frequently when used concurrently with other medications that may impact the metabolism of lamotrigine. Objective: To present the case of a 65-year-old man being treated with lamotrigine and valproic acid who developed mental status changes after the addition of sertraline to his medication regimen, and to compare this case to existing cases reported in the literature. Discussion: Our case adds to the existing literature by demonstrating that patients may experience adverse medication effects despite lamotrigine levels that are normally considered to be in the therapeutic range, highlighting the importance of clinical correlation when obtaining medication levels. Conclusion: Clinicians should use caution interpreting lamotrigine levels when working up delirium, as normal levels may not rule out the development of lamotrigine toxicity.


Author(s):  
Bo‐Hao Zheng ◽  
Sheng Shen ◽  
Kwong‐Fai Wong ◽  
Zi‐Jun Gong ◽  
Wen‐Tao Sun ◽  
...  

2016 ◽  
Vol 27 ◽  
pp. ix125
Author(s):  
L. Orgiano ◽  
A. Dessi ◽  
A. Cubeddu ◽  
E. Lai ◽  
R. Mascia ◽  
...  

2021 ◽  
Author(s):  
Christina Schutt ◽  
Emily Mirizio ◽  
Claudia Salgado ◽  
Miguel Reyes‐Mugica ◽  
Xinjun Wang ◽  
...  

Author(s):  
Jitesh Kumar Sharma ◽  
Rashim Kataria ◽  
Madhur Choudhary ◽  
Devendra Kumar Purohit

Abstract Introduction To present and discuss the clinical presentations, investigations, and treatment options for skull bone tumors. Materials and Methods This study was conducted from January 2019 to December 2019 at the Department of Neurosurgery. During this period, eight patients presented with skull bone tumor in the outpatient department. All patients were thoroughly investigated. Surgery was conducted on six patients and two patients had disseminated carcinoma; hence, surgery was not done. Patients were regularly followed-up after the surgery. Results In our study, out of eight cases, five were females and three were males. We had two cases of fibrous dysplasia, two cases of osteomas, and one case each of brown tumor, metastases from lung carcinoma, metastases from follicular carcinoma of thyroid, and Ewing sarcoma/primitive neuroectodermal tumor (PNET). Excision of tumor was performed where indicated and adjuvant chemo- and radiotherapy was suggested wherever required. Conclusion Bony tumors of the skull are uncommon diseases for the neurosurgeons. These tumors require a careful diagnosis with suitable radiological examinations and proper clinical correlation for proper management.


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