Dynamics of Cerebrospinal Fluid: From Theoretical Models to Clinical Applications

Author(s):  
Laurent Geregele ◽  
Olivier Baledent ◽  
Romain Manet ◽  
Afroditi Lalou ◽  
Slawomir Barszcz ◽  
...  
Author(s):  
Marek Czosnyka ◽  
Zofia Czosnyka ◽  
Olivier Baledent ◽  
Ruwan Weerakkody ◽  
Magdalena Kasprowicz ◽  
...  

2020 ◽  
Vol 78 (3) ◽  
pp. 176-178
Author(s):  
Thiago Ferreira Simões DE SOUZA

Abstract At the beginning of the 20th century, cerebrospinal fluid (CSF) collection and analysis emerged as a promising aid in the diagnosis of diseases of the central nervous system. It was obtained through the established procedure of lumbar puncture, described by Heinrich Quinke in 1891. The search for an alternative way to gather the CSF emerged in animal research, highlighting the cisterna magna as a promising source, with relative safety when performed by someone trained. Described initially and in detail by James Ayer in 1920, the procedure was widely adopted by neurologists and psychiatrists at the time, featuring its multiple advantages and clinical applications. After a period of great procedure use and exponential data collection, its complications and risks relegated the puncture of the cisterna magna as an alternative route that causes fear and fascination in modern Neurology.


2015 ◽  
Vol 8 (8) ◽  
pp. 865-867 ◽  
Author(s):  
A Ian Wong ◽  
Shengqiang Gao ◽  
Mark D Bain ◽  
Brian Fitzsimons ◽  
Ferdinand K Hui

BackgroundCerebrospinal fluid diversion through lumbar drainage catheters is a routine procedure that is used in a variety of clinical applications. Fracture of catheters during insertion or removal may result in retained foreign bodies that may lead to patient morbidity with potential legal ramifications. Fracture resistance is an important component of drain selection.ObjectiveTo analyze catheter integrity to determine which commercially available catheters are most robust and resistant to fracture.MethodsPhysical properties of the commercially available drainage catheters that can be advanced through a Touhy needle were assessed using laboratory equipment and reported. Five types of catheter were analyzed for break load, tensile strength, extension at break, and shear strength.Results and conclusionsOf the five types of catheter, the Arrow catheter showed the greatest resistance to fracture. Of the drainage catheters, the Codman catheter showed the greatest resistance to fracture.


1993 ◽  
Vol 39 (2) ◽  
pp. 309-312 ◽  
Author(s):  
O Gaillard ◽  
D Meillet ◽  
M C Diemert ◽  
L Musset ◽  
J Delattre ◽  
...  

Abstract Complement components have a role in various neurological disorders. Complement C3 can be measured by immunochemical methods, but only radioimmunoassays and electroimmunodiffusion assays (EIDs) are sufficiently sensitive to be applied to biological fluids in which the C3 concentration is low, especially cerebrospinal fluid (CSF). We report a sandwich-type time-resolved immunofluorometric assay (TR-IFMA) for C3 in CSF. The linearity (0.7-3650 micrograms/L) and intra- (CV < 4.8%) and inter-assay (CV < 10.9%) precision were satisfactory and the results agreed with those of EID. The assay is extremely sensitive (< 1 microgram/L) and its analytical range is large and well suited to clinical applications. This simple TR-IFMA is thus a nonisotopic alternative to radioimmunoassay for the quantification of complement C3 in CSF.


Neurographics ◽  
2017 ◽  
Vol 7 (3) ◽  
pp. 199-210 ◽  
Author(s):  
T. Alves ◽  
E.-S. Ibrahim ◽  
B.A. Martin ◽  
D. Malyarenko ◽  
C. Maher ◽  
...  

2018 ◽  
Vol 46 (2) ◽  
pp. 121
Author(s):  
HendG Elsafty ◽  
AshrafM ELAggan ◽  
MohammedA Yousef ◽  
ManalE Badawy

2016 ◽  
Vol 41 (3) ◽  
pp. 456-462 ◽  
Author(s):  
Angela Callear ◽  
Shane Trevor Harvey ◽  
David Bimler

Emotion regulation is a central feature in human emotional development. However, measures based on children’s observable emotion regulation behaviors are largely absent. An inventory of children’s emotion regulation strategies was developed from current measures and four focus group discussions with experts in child behavior and emotion. From there, a 103-item inventory of observable emotion regulation strategies was developed. Multidimensional scaling was used to elicit and analyze similarity data, generated by participants with lay and expert knowledge in children’s emotion regulation engaging in a series of objective sorting tasks. This created a type of “collective working model” which reflects the internal structure of the item collection. The resulting framework provides a model that overlays current theoretical models, allows these models to be discussed and expanded, and the resultant Children’s Emotion Regulation Inventory (ChERI) carries potential usefulness for research or clinical applications.


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