Implementing COPD Precision Medicine in Clinical Practice

Author(s):  
Don D. Sin
Author(s):  
Natalie Jane Colson ◽  
Melissa Adamski

Nutritional genomics is a fast-growing area of precision medicine. It is expected that dietitians will be key players in this area. This chapter discusses the current state of industry, from research to the availability of commercial products, their regulation, and consumer perceptions. Current issues and controversies surrounding the readiness, availability, and delivery of this technology to consumers are examined, and finally, an education framework describing core competencies is presented. The framework aims to provide dietitians with the necessary tools to evaluate and make decisions on the potential for translation of this technology to clinical practice for disease prevention and management.


Author(s):  
Mingyan He ◽  
Jinglin Xia ◽  
Mohamed Shehab ◽  
Xiangdong Wang

2021 ◽  
Author(s):  
Sarah VL Hodge ◽  
Beata Mickiewicz ◽  
Matthew Lau ◽  
Craig N Jenne ◽  
Graham C Thompson

Reliable and efficient diagnosis of pediatric appendicitis is essential for the establishment of a clinical management plan and improvement of patient outcomes. Current strategies used to diagnose a child presenting with a suspected appendicitis include laboratory studies, clinical scores and diagnostic imaging. Although these modalities work in conjunction with each other, one optimal diagnostic strategy has yet to be agreed upon. The recent introduction of precision medicine techniques such as genomics, transcriptomics, proteomics and metabolomics has increased both the diagnostic sensitivity and specificity of appendicitis. Using these novel strategies, the integration of precision medicine into clinical practice via point-of-care technologies is a plausible future. These technologies would assist in the screening, diagnosis and prognosis of pediatric appendicitis.


2019 ◽  
Vol 28 (152) ◽  
pp. 190054 ◽  
Author(s):  
Ian Pavord ◽  
Thomas Bahmer ◽  
Fulvio Braido ◽  
Borja G. Cosío ◽  
Marc Humbert ◽  
...  

The European Respiratory Biologics Forum gathered participants from 21 countries in Madrid, Spain, to discuss the management and treatment of severe asthma in the era of biologics. The current insights on the pathophysiology of severe asthma were discussed, as well as the role of respiratory biologics in clinical practice and strategies for eliminating chronic use of oral corticosteroids. The participants also highlighted the key challenges in identifying patients with severe asthma based on phenotypes, biomarkers and treatable traits, and the existing problems in patient referral to specialist care. The monitoring of treatment was debated and the need for a change towards precision medicine and personalised care was emphasised throughout the meeting. This review provides a summary of the discussions and highlights important concerns identified by the participants regarding the current management of severe asthma.


Author(s):  
Panagiotis Cherouveim ◽  
Antonios Athanasiou ◽  
Evangelos Paraskevaidis

Personalised medicine and precision medicine are being applied in more medical fields in the last years. The need for personalisation is especially pronounced in cervical pathology, since in the majority of cases an abnormal screening test does not necessarily imply high-grade lesion, regardless of whether the screening test is cytology or HPV testing. The chapter aims to summarize the exact added value that mRNA presents for management in clinical practice as well as highlight comparative advantages and disadvantages with other triage strategies.


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