Strychnos henningsii Gilg. Strychnos spinosa Lam. Strychnos usambarensis Gilg. Loganiaceae

2021 ◽  
pp. 991-995
Author(s):  
Rainer W. Bussmann ◽  
Narel Y. Paniagua-Zambrana ◽  
Grace N. Njoroge
Keyword(s):  
2021 ◽  
Author(s):  
Helena Correia ◽  
Maria Wanda Emanuelson ◽  
Moisés Nhantumbo ◽  
Paulo Andrassone ◽  
Graça Cumbi ◽  
...  

Abstract Background Epilepsy is a chronic brain disease that affects about 50 million people worldwide, mainly in developing countries. It is treated with anticonvulsant drugs, but in some cases, conventional anticonvulsants have not been effective, leading patients to turn to alternative herbal treatments. The study aimed to identify plants used in traditional medicine for the treatment of epilepsy in southern Mozambique, record the parts used, the method of preparation as well as the mode of administration. Methodology: The study was conducted between April to June 2019. 53 Traditional Medicine Practitioners were interviewed using a semi-structured questionnaire. The data was analyzed by calculating the Percentage of Citation (%FC) and Informant Factor Consensus (IFC). Results A total of 32 medicinal plants belonging to 18 botanical families were identified for the treatment of epilepsy in the southern part of Mozambique. The species, Hugonia orientalis Engl (22.64%), Maclura africana Bur (16.98%), Strychnos spinosa Lam (13.21%), Terminalia sericea Bruch ex DC (13.21%) and Manilkara mochisia (Bark) Dubard (11.32%) were the most cited. The families Annonaceae and Menispermaceae (4 species) were the most representative in number of species. The root was the most commonly used plant part (54.2%), the frequently used preparation mode was decoction (71%), and administration of the remedies was often by oral route. Conclusion Medicinal plants still play an important role in primary health care in the study area. However there is a need to develop pharmacological studies based on these plants to understand the mechanism of action of the bioactive compounds and for the future development of new and more effective anticonvulsant drugs


2020 ◽  
Vol 24 (2) ◽  
pp. 197-206
Author(s):  
H. Hassan ◽  
K.I. Omoniyi ◽  
F.G. Okibe ◽  
A.A. Nuhu ◽  
E.G. Echioba

The biosynthesis of nanoparticles has been proposed as a cost effective and environmentally friendly alternative to chemical and physical methods. The present work investigates the synthesis of titanium oxide nanoparticles (TiO2 NPs) by green approach using Strychnos spinosa and Blighia sapida leave extracts. The detailed characterization of the TiO2 NPs was carried out using UV-Visible Spectroscopy, Scanning Electron Microscopy (SEM), X- ray Diffraction (XRD), and Fourier-Transform Infrared (FTIR) Spectroscopy. The green synthesized TiO2 NPs excitation was confirmed using UV–Vis spectrophotometer at 270 and 290 nm for Strychnos spinosa and Blighia sapida respectively. SEM revealed that the synthesized TiO2 NPs were spherical and crystalline in nature. The overall sizes are 40 and 50 nm for Strychnos spinosa and Blighia sapida respectively. FTIR spectroscopic analysisshowed the presence of flavonoids, polyphenols and amide groups likely to be responsible for the green synthesis of titanium oxide nanoparticles using S. Spinosa and B .sapida aqueous leaf extracts. The XRD pattern showed the characteristic Bragg peaks of (111), (200), (220) and (311) facets of the anatase titanium oxide nanoparticles and confirmed that these nanoparticles were crystalline and spherical in nature. Furthermore, the green synthesized TiO2 NPs wound healing activity was examined in the excision wound model by measuring wound closure, histopathology and protein profiling. This revealed significant wound healing activity in Albino rats. In the present study, topical application ofnanoformulated extracts of B. sapidaa nd S. spinosa significantly accelerated wound healing with 20% nanoformulated ointment having the highest percentage wound contraction ability comparable with gentamicin (a commercially sold antimicrobial agent used in dressing wounds). In conclusion, this work proved the capability of using TiO2 NPs to deliver a novel therapeutic route for wound treatment in clinical practice. Keywords: Wound healing activity; SEM; TiO2; XRD; FTIR; UV–Vis spectroscopy.


Exotic Fruits ◽  
2018 ◽  
pp. 293-296
Author(s):  
Sueli Rodrigues ◽  
Edy Sousa de Brito ◽  
Ebenezer de Oliveira Silva
Keyword(s):  

2017 ◽  
Vol 11 (4) ◽  
pp. 71-78
Author(s):  
U. Asuzu Chinwe ◽  
O. Nwosu Maria
Keyword(s):  

Author(s):  
Hospice Gérard Gracias Avakoudjo ◽  
Rodrigue Idohou ◽  
Kolawolé Valère Salako ◽  
Achille Hounkpèvi ◽  
Mamidou Witabouna Koné ◽  
...  

2016 ◽  
Vol 12 (12) ◽  
pp. 157 ◽  
Author(s):  
Ousmane Niass ◽  
Serigne Omar Sarr ◽  
Baba Dieye ◽  
Amadou Diop ◽  
Yerim Mbagnick Diop

Against the scourge of malaria in Africa and the development of chemo-resistance, discovering new natural cures is a major concern for many researchers. As a consequence, the present study was carried out in order, first, to identify the phytochemical compounds, and second, to assess the antiplasmodial activity, of three medicinal plants extracts, selected from an ethno-botany survey conducted in Senegal. The parts of the plants used were Strychnos spinosa (Strychnaceae) leaves and stems, Combretum glutinosum (Combretaceae) barks, and the whole aerial part of Pennisetum polystachion (Poaceae). Among these plants, the hydromethanolic extracts of Strychnos spinosa stems showed the most important activity against Plasmodium falciparum strains, with a IC50 of 15 μg/ml, followed by the leaves chlorophormic extracts and the ethyl acetate extracts of Pennisetum polystachion, with respective IC50 of 20 μg/ml and 21 μg/ml. Combretum glutinosum extracts showed the least important activity, in all tests.


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