Challenges and Limitations in Clustering Blood Donor Hemoglobin Trajectories

2020 ◽  
pp. 72-84
Author(s):  
Marieke Vinkenoog ◽  
Mart Janssen ◽  
Matthijs van Leeuwen
Keyword(s):  
Blood Donor

scholarly journals Physiological Parameters to Identify Suitable Blood Donor Cows for Preparation of Platelet Rich Plasma

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2296
Author(s):  
Anna Lange-Consiglio ◽  
Rosangela Garlappi ◽  
Chiara Spelta ◽  
Antonella Idda ◽  
Stefano Comazzi ◽  
...  
Keyword(s):  
Blood Donor ◽  
Blood Donors ◽  
Platelet Rich Plasma ◽  
Bovine Mastitis ◽  
Field Conditions ◽  
Blood Collection ◽  
Experimental Conditions ◽  
Acute Mastitis ◽  
Donor Cows ◽  
The Ideal

Platelet rich plasma (PRP) has been shown to be beneficial in the treatment of bovine mastitis, with an action comparable to that of antibiotics. Autologous treatment is feasible in experimental conditions but is difficult to apply in field conditions, particularly in acute mastitis. The ideal scenario would be to have heterologous PRP stored on every farm so that it is readily available when needed. In this paper, we analysed data collected during bovine mastitis treatment with heterologous PRP produced by casual donor cows on several farms. We tried to identify parameters which might be useful to identify the most suitable cows to be used as blood donors, to obtain the highest yield of PRP. Variables considered for each animal were the age, the parity, the date of the last parturition, the season of blood collection, the site of blood collection (jugular or mammary vein) and the reproductive status e.g., pregnant or not pregnant. There were statistically significant differences for all the variables considered from the 135 blood cows, except for the blood collection season. The highest yield of PRP was associated with nonpregnancy blood collection within three months of parturition, parity 3 or 4, and blood collection from the mammary vein.

scholarly journals Altruism in blood donation: Out of sight out of mind? Closing donation centers influences blood donor lapse

2021 ◽  
Vol 67 ◽  
pp. 102495
Author(s):  
Tjeerd W. Piersma ◽  
René Bekkers ◽  
Wim de Kort ◽  
Eva-Maria Merz
Keyword(s):  
Blood Donor ◽  
Blood Donation

scholarly journals Comparison of Five Serological Assays for the Detection of SARS-CoV-2 Antibodies

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 78
Author(s):  
Anja Dörschug ◽  
Julian Schwanbeck ◽  
Andreas Hahn ◽  
Anke Hillebrecht ◽  
Sabine Blaschke ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Blood Donor ◽  
Immunoglobulin G ◽  
The Other ◽  
Specific Antibodies ◽  
Diagnostic Assays ◽  
Immunoglobulin Class ◽  
Corona Virus ◽  
Immunoglobulin Subclass

Serological assays can contribute to the estimation of population proportions with previous immunologically relevant contact with the Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) virus. In this study, we compared five commercially available diagnostic assays for the diagnostic identification of SARS-CoV-2-specific antibodies. Depending on the assessed immunoglobulin subclass, recorded sensitivity ranged from 17.0% to 81.9% with best results for immunoglobulin G. Specificity with blood donor sera ranged from 90.2% to 100%, with sera from EBV patients it ranged from 84.3% to 100%. Agreement from fair to nearly perfect was recorded depending on the immunoglobulin class between the assays, the with best results being found for immunoglobulin G. Only for this immunoglobulin class was the association between later sample acquisition times (about three weeks after first positive PCR results) and positive serological results in COVID-19 patients confirmed. In conclusion, acceptable and comparable reliability for the assessed immunoglobulin G-specific assays could be shown, while there is still room for improvement regarding the reliability of the assays targeting the other immunoglobulin classes.

scholarly journals Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor

2021 ◽  
Vol 9 (6) ◽  
Author(s):  
Charlotte Nielsen Agergaard ◽  
Thure Mors Haunstrup ◽  
Anne‐Louise Fjordside ◽  
John Baech ◽  
Rudi Steffensen ◽  
...  
Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Blood Donor ◽  
Fresh Frozen Plasma ◽  
Obstetric Patient ◽  
Fresh Frozen ◽  
Male Blood Donor ◽  
Frozen Plasma

Managing patients with hepatitis C

1993 ◽  
Vol 31 (16) ◽  
pp. 61-62 ◽  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
General Practitioners ◽  
Blood Donor ◽  
The Uk

All blood donated in the UK is tested for antibodies to hepatitis C virus (HCV), and 1 in 1800 samples is confirmed positive.1 Blood from anti-HCV positive donors is discarded to avoid transmission of the virus, and in most centres these donors are contacted and advised to see their general practitioners. In this article we discuss the management of patients found to be anti-HCV positive either through the blood donor service or as a result of investigations for other indications.

A Walking Blood Donor Program for Seriously Ill Premature Infants

Transfusion ◽  
2003 ◽  
Vol 16 (4) ◽  
pp. 366-369 ◽  
Author(s):  
P. G. Hattersley ◽  
B. W. Goetzman ◽  
S. Gross ◽  
W. J. Blankenship
Keyword(s):  
Premature Infants ◽  
Blood Donor ◽  
Seriously Ill

scholarly journals APO E Genotype and Familial Hypercholesterolaemia

1997 ◽  
Vol 34 (5) ◽  
pp. 534-536 ◽  
Author(s):  
E B Duly ◽  
A J Ward ◽  
C W Kirk ◽  
N C Nevin ◽  
T R Trinick ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Blood Donor ◽  
Familial Hypercholesterolaemia ◽  
Chain Reaction ◽  
Cholesterol Levels ◽  
Apo E ◽  
Apolipoprotein E Genotypes ◽  
Ε4 Allele ◽  
Polymerase Chain ◽  
Apo E Genotype

Apolipoprotein E genotypes were measured in 83 patients with familial hypercholesterolaemia (FH) and in 175 blood donor controls. Following DNA extraction from peripheral blood, each sample was genotyped for the Apo E polymorphism by polymerase chain reaction. No significant differences were found in the levels of the ε2 and ε3 alleles between the two groups, while the ε4 allele was approximately twice as prevalent in the FH patients as in controls ( P = 0·006, df = 1). Of the FH patients, 8·4% were homozygous for the ε4 allele while this genotype was rare in controls ( P = 0·009, df = 1). These results suggest that the ε4 allele is over represented in the FH population and may contribute to increased cholesterol levels and consequent vascular disease.

Acute nosocomial HCV infection detected by NAT of a regular blood donor

Transfusion ◽  
2002 ◽  
Vol 42 (6) ◽  
pp. 759-765 ◽  
Author(s):  
Bryce Larke ◽  
Yu-Wen Hu ◽  
Mel Krajden ◽  
Vito Scalia ◽  
Sean K. Byrne ◽  
...  
Keyword(s):  
Blood Donor ◽  
Hcv Infection
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