scholarly journals Physiological Parameters to Identify Suitable Blood Donor Cows for Preparation of Platelet Rich Plasma

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2296
Author(s):  
Anna Lange-Consiglio ◽  
Rosangela Garlappi ◽  
Chiara Spelta ◽  
Antonella Idda ◽  
Stefano Comazzi ◽  
...  
Keyword(s):  
Blood Donor ◽  
Blood Donors ◽  
Platelet Rich Plasma ◽  
Bovine Mastitis ◽  
Field Conditions ◽  
Blood Collection ◽  
Experimental Conditions ◽  
Acute Mastitis ◽  
Donor Cows ◽  
The Ideal

Platelet rich plasma (PRP) has been shown to be beneficial in the treatment of bovine mastitis, with an action comparable to that of antibiotics. Autologous treatment is feasible in experimental conditions but is difficult to apply in field conditions, particularly in acute mastitis. The ideal scenario would be to have heterologous PRP stored on every farm so that it is readily available when needed. In this paper, we analysed data collected during bovine mastitis treatment with heterologous PRP produced by casual donor cows on several farms. We tried to identify parameters which might be useful to identify the most suitable cows to be used as blood donors, to obtain the highest yield of PRP. Variables considered for each animal were the age, the parity, the date of the last parturition, the season of blood collection, the site of blood collection (jugular or mammary vein) and the reproductive status e.g., pregnant or not pregnant. There were statistically significant differences for all the variables considered from the 135 blood cows, except for the blood collection season. The highest yield of PRP was associated with nonpregnancy blood collection within three months of parturition, parity 3 or 4, and blood collection from the mammary vein.

scholarly journals Change in haematological and selected biochemical parameters measured in feline blood donors and feline whole blood donated units

2016 ◽  
Vol 19 (4) ◽  
pp. 375-381 ◽  
Author(s):  
Eva Spada ◽  
Daniela Proverbio ◽  
Luciana Baggiani ◽  
Giada Bagnagatti De Giorgi ◽  
Elisabetta Ferro ◽  
...  
Keyword(s):  
Blood Donor ◽  
Whole Blood ◽  
Blood Cells ◽  
Biochemical Parameters ◽  
Blood Donors ◽  
White Blood Cells ◽  
Mean Difference ◽  
Blood Collection ◽  
Distribution Width ◽  
Selection Of

Objectives The quality of whole blood (WB) units is influenced by many factors, starting with selection of donors and the method of blood collection. The aim of this study was to investigate the changes that occur in haematological and selected biochemical parameters in blood transferred from a feline blood donor to feline WB unit. Methods Data from 27 feline blood donations were used in this study. Cats were anaesthetised with a combination of tiletamine and zolazepam. Blood (10 ml/kg body weight to a maximum of 60 ml/cat) was collected in citrate–phosphate–dextrose–adenine (CPDA) anticoagulant. Lactated Ringer’s solution (10 ml/kg) was administered intravenously starting halfway through the donation. Haematological and selected biochemical parameters (complete blood count, free haemoglobin, % haemolysis, glucose, sodium, potassium, pH) were measured in the blood donor before donation and in the corresponding donated WB unit soon after collection. Results Significant decreases occurred between blood donor and WB unit in red blood cells (mean difference −1.06 × 1012/l; P <0.0001), haemoglobin (mean difference −1.6 g/dl; P <0.0001), haematocrit (mean difference −4.6%; P <0.0001), red cell distribution width (mean difference −0.9%; P = 0.0003), white blood cells (mean difference −2.17 × 109/l; P <0.0001), pH (mean difference −0.5; P <0.0001) and potassium (mean difference −1.4 mmol/l; P <0.0001). Significant increases occurred between blood donor and WB unit in platelets (mean difference +87.00 ×109/l; P = 0.0039), glucose (mean difference +25.42 mmol/l; P <0.0001) and sodium (mean difference +20 mmol/l; P <0.0001). Conclusions and relevance When using a blood collection protocol with intravenous fluid administration midway through the donation and a CPDA:blood ratio of 1:7, there were significant changes in both the haematological and biochemical characteristics between the blood donors and WB units. The majority of these changes may be the result of the anticoagulants used for storage. Understanding these changes may assist selection of blood donors and help prediction of the characteristics of the donated WB unit.

scholarly journals Android-Based Geolocation Technology on a Blood Donation System (BDS) Using the Dijkstra Algorithm

2021 ◽  
pp. 1
Author(s):  
Syaiful Ahdan ◽  
Setiawansyah Setiawansyah
Keyword(s):  
Information System ◽  
Blood Donor ◽  
Mobile Application ◽  
Blood Donors ◽  
Blood Donation ◽  
Human Life ◽  
Blood Collection ◽  
Dijkstra Algorithm ◽  
System Testing ◽  
Test Characteristics

Blood transfusion is an activity that is often carried out in order to save human life. The availability of appropriate bloodstock is crucial for use during special medical conditions. Therefore, the blood collection center must ensure availability; therefore, it needs to recruit active blood donors, difficult patients to find blood stocks, which will be discussed in this study. The contribution of this research is to design an information system that can find blood donors in the Bandar Lampung area with geolocation technology and use the Dijkstra algorithm to determine the closest route, with a system developed on the Android platform. The system can recommend donors to patients who need blood according to the patient's qualifications. Results obtained are an android-based mobile application that can search for geolocation-based blood donors using the Dijkstra algorithm, which can map the location of the nearest blood donor based on the patient's location. Based on data obtained from the results of system testing on functionality and usability, the system can map the location of blood donors and provide blood donor recommendations for patients in need. System testing is carried out using the ISO 9126 standard using the usability aspect, which consists of four test characteristics: the understanding aspect, the learning aspect, the ability aspect, and the operability aspect, and the attractiveness aspect.

scholarly journals Blood Donation Program in Malaysia: Government Initiatives towards Attracting Volunteer Blood Donors

2018 ◽  
Vol 7 (4.15) ◽  
pp. 240
Author(s):  
Nur Hairani Abd Rahman ◽  
Muhammad Asri Mohd Ali ◽  
Mohammed Farhan Md. Yusof
Keyword(s):  
Blood Supply ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Donation ◽  
Public Awareness ◽  
Supply And Demand ◽  
Current Situation ◽  
Blood Collection ◽  
Volunteer Blood Donor ◽  
The Government

Millions of people need blood because of many reasons such as accidents, routine surgeries, treatment of serious diseases such as cancer and thalassemia. In many countries, the availability of blood product depends on a small number of volunteer donors, including Malaysia. Present trends in blood collection and capacity usage in Malaysia have raised concerns about the ability to meet potential needs. To ensure an adequate blood supply in health facilities is a challenging task for the government especially Ministry of Health Malaysia. It is important to develop a program with influential initiatives that can help to boost public interest and willingness to involve in blood donation program. This study aims to identify and examine the initiatives conducted by the government in order to attract the interest of public to become volunteer blood donor. This study identified that there were five main initiatives implemented by the government to attract public to donate blood, namely: (a) intensive advertising (via mainstream television and radio channels); (b) mobile blood transfusion service center; (c) incentives to blood donors; (d) establishments of donation suites, and; (e) collaboration with other government institution for blood donation campaign. Although current situation showed significant changes in terms of public awareness and willingness towards this program, but there are rooms for improvement for the government to consider in maintaining the balance between blood supply and demand in the country. Focusing on public to register, as frequent or repeated volunteer blood donor, is obviously one of the main available option that current situation need to strengthen. 

Green Synthesis and Enhanced CO2 Capture Performance of Perfluorinated Cerium-Based Metal-Organic Frameworks with UiO-66 and MIL-140 Topology

2018 ◽  
Author(s):  
Roberto D’Amato ◽  
Anna Donnadio ◽  
Mariolino Carta ◽  
Claudio Sangregorio ◽  
Riccardo Vivani ◽  
...  
Keyword(s):  
Photoelectron Spectroscopy ◽  
Metal Organic Frameworks ◽  
Isosteric Heat ◽  
Experimental Conditions ◽  
Cerium Ammonium Nitrate ◽  
Ideal Adsorbed Solution Theory ◽  
Metal Organic ◽  
Adsorbed Solution ◽  
Better Than ◽  
The Ideal

Reaction of cerium ammonium nitrate and tetrafluoroterephthalic acid in water afforded two new metal-organic frameworks with UiO-66 [F4_UiO-66(Ce)] and MIL-140 [F4_MIL-140A(Ce)] topologies. The two compounds can be obtained in the same experimental conditions, just by varying the amount of acetic acid used as crystallization modulator in the synthesis. Both F4_UiO-66(Ce) and F4_MIL-140A(Ce) feature pores with size < 8 Å, which classifies them as ultramicroporous. Combination of X-ray photoelectron spectroscopy and magnetic susceptibility measurements revealed that both compounds contain a small amount of Ce(III), which is preferentially accumulated near the surface of the crystallites. The CO<sub>2</sub> sorption properties of F4_UiO-66(Ce) and F4_MIL-140A(Ce) were investigated, finding that they perform better than their Zr-based analogues. F4_MIL-140A(Ce) displays an unusual S-shaped isotherm with steep uptake increase at pressure < 0.2 bar at 298 K. This makes F4_MIL-140A(Ce) exceptionally selective for CO<sub>2</sub> over N<sub>2</sub>: the calculated selectivity, according to the ideal adsorbed solution theory for a 0.15:0.85 mixture at 1 bar and 293 K, is higher than 1900, amongst the highest ever reported for metal-organic frameworks. The calculated isosteric heat of CO<sub>2 </sub>adsorption is in the range of 38-40 kJ mol<sup>-1</sup>, indicating a strong physisorptive character.

scholarly journals Reduction of exposure to blood donors in preterm infants submitted to red blood cell transfusions using pediatric satellite packs

2013 ◽  
Vol 31 (3) ◽  
pp. 285-292 ◽  
Author(s):  
Cristina Lika Uezima ◽  
Ariane Moreira Barreto ◽  
Ruth Guinsburg ◽  
Akemi Kuroda Chiba ◽  
José Orlando Bordin ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Infants ◽  
Blood Donor ◽  
Blood Donors ◽  
Newborn Infants ◽  
Median Number ◽  
Erythrocyte Transfusion ◽  
Factors Associated ◽  
Group 2 ◽  
Group 1

OBJECTIVE: In preterm newborn infants transfused with erythrocytes stored up to 28 days, to compare the reduction of blood donor exposure in two groups of infants classified according to birth weight. METHODS: A prospective study was conducted with preterm infants with birth weight <1000g (Group 1) and 1000-1499g (Group 2), born between April, 2008 and December, 2009. Neonates submitted to exchange transfusions, emergency erythrocyte transfusion, or those who died in the first 24 hours of life were excluded. Transfusions were indicated according to the local guideline using pediatric transfusion satellite bags. Demographic and clinical data, besides number of transfusions and donors were assessed. . Logistic regression analysis was performed to determine factors associated with multiple transfusions. RESULTS: 30 and 48 neonates were included in Groups 1 and 2, respectively. The percentage of newborns with more than one erythrocyte transfusion (90 versus 11%), the median number of transfusions (3 versus 1) and the median of blood donors (2 versus 1) were higher in Group 1 (p<0.001), compared to Group 2. Among those with multiple transfusions, 14 (82%) and one (50%) presented 50% reduction in the number of blood donors, respectively in Groups 1 and 2. Factors associated with multiple transfusions were: birth weight <1000g (OR 11.91; 95%CI 2.14-66.27) and presence of arterial umbilical catheter (OR 8.59; 95%CI 1.94-38.13), adjusted for confounders. CONCLUSIONS: The efficacy of pediatrics satellites bags on blood donor reduction was higher in preterm infants with birth weight <1000g.

Iron deficiency among blood donors: experience from the Danish Blood Donor Study and from the Copenhagen ferritin monitoring scheme

2017 ◽  
Vol 29 (S1) ◽  
pp. 23-27 ◽  
Author(s):  
A. S. Rigas ◽  
O. B. Pedersen ◽  
K. Magnussen ◽  
C. Erikstrup ◽  
H. Ullum
Keyword(s):  
Iron Deficiency ◽  
Blood Donor ◽  
Blood Donors ◽  
Monitoring Scheme

scholarly journals The Photocatalytic Activity of Cement in Reducing Air Pollutants

2019 ◽  
Vol 8 (6S3) ◽  
pp. 1422-1424
Keyword(s):  
Climate Change ◽  
Air Pollution ◽  
Global Warming ◽  
Photocatalytic Activity ◽  
Ion Chromatography ◽  
Air Pollutants ◽  
Experimental Conditions ◽  
Open Environment ◽  
Physical And Chemical ◽  
The Ideal

Air pollution is the major concern in the recent years because of causing imbalance to the ecosystem and also increases global warming and climate change. This paper, tries to investigate the applicability of photo catalytic cement in removing the pollutants under partially controlled and simpler experimental conditions such that it mimics the ideal state of its use, that is the natural open environment where it always is susceptible to complex physical and chemical interactions. It also gives an overview of the concentrations of the contaminants reduced not limiting to NOx residues alone, by employing Ion Chromatography instead of NOx analyzers.

scholarly journals Evaluation of platelet-rich plasma gel as an angiogenesis-inducing agent in canineadvancement skin flaps

2020 ◽  
Vol 40 (6) ◽  
pp. 474-478
Author(s):  
Grazielle A.S. Aleixo ◽  
Maria C.O.C. Coelho ◽  
Telga L.A. Almeida ◽  
Márcia F. Pereira ◽  
Miriam N. Teixeira ◽  
...  
Keyword(s):  
Blood Vessel ◽  
Skin Color ◽  
Platelet Rich Plasma ◽  
Skin Flap ◽  
Skin Flaps ◽  
Experimental Conditions ◽  
Significant Difference ◽  
Experimental Group ◽  
Prp Gel ◽  
Made In

ABSTRACT: This work aimed to evaluate the effect of platelet-rich plasma (PRP) on advancement skin flaps in dogs regarding improvement of vascularization, with focus on increasing its viable area, since there are reports that it is a potential angiogenesis stimulator. The experimental group was composed of eight adult bitches, in which two advancement skin flaps were made in the ventral abdominal region. No product was applied in the control flap (CF), while PRP was used in the contralateral flap, called treated flap (TF). The areas were clinically evaluated every two days until the 7th postoperative day regarding skin color and presence of necrosis. At 10 days, both flaps were removed and submitted to histological examination and blood vessel morphometry. The vessels counted in each group were statistically analyzed by the F-test at 1% probability. Results showed no significant difference in macroscopic changes in the wound, or CF and TF vascularization, thus suggesting that PRP gel did not improve advancement skin flap angiogenesis in bitches under the experimental conditions in which this research was developed.

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