Developing Digital Awareness at School: A Fundamental Step for Cybersecurity Education

Author(s):  
Isabella Corradini ◽  
Enrico Nardelli
Keyword(s):  
2004 ◽  
Vol 9 (3) ◽  
pp. 441-456 ◽  
Author(s):  
Laurie Weingart ◽  
Philip Smith ◽  
Mara Olekalns

AbstractThe examination of negotiation processes is seen by many researchers as an insurmountable task largely because the required methods are unfamiliar and labor-intensive. In this article, we shed light on a fundamental step in studying negotiation processes, the quantitative coding of data. Relying on videotapes as the primary source of data, we review the steps required to extract usable quantitative data and the lessons we've learned in doing so in our own research. We review our experience working with one large negotiation dataset, Towers Market II, to illustrate two steps within the larger research process: developing a coding scheme and coding the data. We then go on to discuss some of the issues that need to be resolved before data analysis begins.


2020 ◽  
Author(s):  
NH Thuan ◽  
Andreas Drechsler ◽  
Pedro Antunes

© 2019 by the Association for Information Systems. Posing research questions represents a fundamental step to guide and direct how researchers develop knowledge in research. In design science research (DSR), researchers need to pose research questions to define the scope and the modes of inquiry, characterize the artifacts, and communicate the contributions. Despite the importance of research questions, research provides few guidelines on how to construct suitable DSR research questions. We fill this gap by exploring ways of constructing DSR research questions and analyzing the research questions in a sample of 104 DSR publications. We found that about two-thirds of the analyzed DSR publications actually used research questions to link their problem statements to research approaches and that most questions focused on solving problems. Based on our analysis, we derive a typology of DSR question formulation to provide guidelines and patterns that help researchers formulate research questions when conducting their DSR projects.


2014 ◽  
Vol 136 (11) ◽  
Author(s):  
M. Lindsey Williams ◽  
Atila Ertas ◽  
Derrick Tate

Inherent in biologically inspired design (BID) is the selection of one or more analogs from which one or more strategies are extracted and transferred into the engineering domain. The selection of an analog is a fundamental step in biomimetic process, but locating relevant biological analogies can be challenging. Often, designers may fixate on an analogy or choose an established analogy without rigorous examination of alternatives. This practice is problematic—as basing a new design on an invalid assumption can lead to suboptimal results. This paper makes contribution to evaluation of analogy utility. The contribution is made by combining stochastic multicriteria acceptability analysis (SMAA) with a set of criteria, derived from BID, to assist multidisciplinary decision makers (DMs) in evaluating candidate design analogs. The resulting framework, which we call the biotransferability framework, is being developed to assist multidisciplinary teams to choose, rank, or sort candidate design analogs by assessing biology-to-engineering transfer risk.


Author(s):  
F. Ambrosetti ◽  
T. H. Olsen ◽  
P. P. Olimpieri ◽  
B. Jiménez-García ◽  
E. Milanetti ◽  
...  

AbstractMonoclonal antibodies (mAbs) are essential tools in the contemporary therapeutic armoury. Understanding how these recognize their antigen is a fundamental step in their rational design and engineering. The rising amount of publicly available data is catalysing the development of computational approaches able to offer valuable, faster and cheaper alternatives to classical experimental methodologies used for the study of antibody-antigen complexes.Here we present proABC-2, an update of the original random-forest antibody paratope predictor, based on a convolutional neural network algorithm. We also demonstrate how the predictions can be fruitfully used to drive the docking in HADDOCK.The proABC-2 server is freely available at: https://bianca.science.uu.nl/proabc2/.


TEM Journal ◽  
2020 ◽  
pp. 633-640
Author(s):  
Asma Cherif

With the advent of information sharing technologies, users can share and collaborate in performing common tasks through the use of distributed collaborative applications. Specifically, Distributed Collaborative Editors (DCE) are more and more used in many fields including healthcare, education, software engineering, military, etc. However, all proposed DCE frameworks focused on coordination algorithms, i.e. how to ensure data convergence, while very little attention was given to addressing the design of DCE which shall be the fundamental step for DCE frameworks construction. In this article, we analyze and design DCE as the structure of five layers comprising classifiers, relations among them, and their main properties. We contribute in two areas. First, we define a generic DCE architecture that captures organization, business and software aspects of DCE. Secondly, we propose a pattern-based design that emphasizes good design principles for the business core of DCE. This design will allow DCE researchers and developers to converge towards the same generic framework while improving the quality and performance of proposed DCE applications and tools.


Molecules ◽  
2021 ◽  
Vol 26 (20) ◽  
pp. 6255
Author(s):  
Gabriele Sciacca ◽  
Petra Martini ◽  
Sara Cisternino ◽  
Liliana Mou ◽  
Jonathan Amico ◽  
...  

Cyclotron-based radionuclides production by using solid targets has become important in the last years due to the growing demand of radiometals, e.g., 68Ga, 89Zr, 43/47Sc, and 52/54Mn. This shifted the focus on solid target management, where the first fundamental step of the radiochemical processing is the target dissolution. Currently, this step is generally performed with commercial or home-made modules separated from the following purification/radiolabelling modules. The aim of this work is the realization of a flexible solid target dissolution system to be easily installed on commercial cassette-based synthesis modules. This would offer a complete target processing and radiopharmaceutical synthesis performable in a single module continuously. The presented solid target dissolution system concept relies on an open-bottomed vial positioned upon a target coin. In particular, the idea is to use the movement mechanism of a syringe pump to position the vial up and down on the target, and to exploit the heater/cooler reactor of the module as a target holder. All the steps can be remotely controlled and are incorporated in the cassette manifold together with the purification and radiolabelling steps. The performance of the device was tested by processing three different irradiated targets under different dissolution conditions.


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