Advanced Functional Polymers for Biomedical Applications: Drug, Sensor, Diagnosis, and Prognosis

2021 ◽  
pp. 181-196
Author(s):  
Kevser Kuşat ◽  
Sinan Akgöl
Keyword(s):  
Biomedical Applications ◽  
Functional Polymers ◽  
Diagnosis And Prognosis

scholarly journals Developing Advanced Functional Polymers for Biomedical Applications

2020 ◽  
Vol 21 (2) ◽  
pp. 273-275
Author(s):  
Jukka Seppälä ◽  
Bas van Bochove ◽  
Andreas Lendlein
Keyword(s):  
Biomedical Applications ◽  
Functional Polymers

scholarly journals Editorial: Design, Synthesis and Biomedical Applications of Functional Polymers

2021 ◽  
Vol 9 ◽  
Author(s):  
Changkui Fu ◽  
Chongyu Zhu ◽  
Christopher V. Synatschke ◽  
Xiaoyong Zhang
Keyword(s):  
Biomedical Applications ◽  
Functional Polymers ◽  
Design Synthesis

Multicomponent polymerization toward biodegradable polymers with diverse responsiveness in tumor microenvironments

2020 ◽  
Vol 11 (6) ◽  
pp. 1198-1210 ◽  
Author(s):  
Junnan He ◽  
Nan Zheng ◽  
Dan Xie ◽  
Yubin Zheng ◽  
Wangze Song
Keyword(s):  
Biodegradable Polymers ◽  
Biomedical Applications ◽  
Functional Polymers ◽  
Tumor Microenvironments

Multicomponent polymerization (MCP), as a powerful synthetic tool, has been widely utilized to prepare diverse functional polymers for optical, electronic, and biomedical applications.

scholarly journals Poly(Boc-Acryloyl Hydrazide): Optimisation of RAFT Polymerisation Through Modulation of Temperature

2019 ◽  
Author(s):  
Oliver Creese ◽  
Pavan Adoni ◽  
Guanlong Su ◽  
Francisco Fernandez-Trillo
Keyword(s):  
Biomedical Applications ◽  
Functional Polymers ◽  
Effect Of Temperature ◽  
Biological Applications ◽  
Polymer Scaffold ◽  
Raft Agent ◽  
Kinetics Of

Poly(acryloyl hydrazide) is a versatile polymer scaffold readily functionalised through post-polymerisation modification with aldehydes to yield polymers with biological applications. Here we report the effect of temperature on the RAFT polymerisation N’-(tert-butoxycarbonyl)acryloyl hydrazide (1) and demonstrate that by carefully selecting this polymerisation temperature, a compromise between kinetics of polymerisation and degradation of the RAFT agent is achieved. This new methodology gives greater control over the polymerisation process, allowing the synthesis of Boc-protected poly(acryloyl hydrazide) with high degrees of polymerisation while still maintaining low dispersities. Our results provide new insights into the synthesis of functional polymers, and should be of interest to those working on the synthesis of polymers for biomedical applications by RAFT polymerisation.

Applications of Scanning Microscopy in Biomedical Research

1968 ◽  
Vol 26 ◽  
pp. 354-355
Author(s):  
T. L. Hayes
Keyword(s):  
Information Content ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Dental Enamel ◽  
Resolving Power ◽  
Whole Mount ◽  
Two Parameters ◽  
Content Information ◽  
Sectioned Tissue

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.

How SIMS microscopy can be used in medicine

1992 ◽  
Vol 50 (2) ◽  
pp. 1602-1603
Author(s):  
Philippe Fragu
Keyword(s):  
Mass Spectrometry ◽  
Biomedical Applications ◽  
Secondary Ion Mass Spectrometry ◽  
Chemical Elements ◽  
Biological Applications ◽  
The Past ◽  
Potential Source ◽  
Secondary Ion ◽  
Chemical Integrity ◽  
Scientific Endeavour

The identification, localization and quantification of intracellular chemical elements is an area of scientific endeavour which has not ceased to develop over the past 30 years. Secondary Ion Mass Spectrometry (SIMS) microscopy is widely used for elemental localization problems in geochemistry, metallurgy and electronics. Although the first commercial instruments were available in 1968, biological applications have been gradual as investigators have systematically examined the potential source of artefacts inherent in the method and sought to develop strategies for the analysis of soft biological material with a lateral resolution equivalent to that of the light microscope. In 1992, the prospects offered by this technique are even more encouraging as prototypes of new ion probes appear capable of achieving the ultimate goal, namely the quantitative analysis of micron and submicron regions. The purpose of this review is to underline the requirements for biomedical applications of SIMS microscopy.Sample preparation methodology should preserve both the structural and the chemical integrity of the tissue.

Morphologic differences between abdominal and inguinal testes in stallions

1987 ◽  
Vol 45 ◽  
pp. 820-821
Author(s):  
F. Al-Bagdadi ◽  
D. Hoyt ◽  
P. Karns ◽  
G. Martin ◽  
M. Memon ◽  
...  
Keyword(s):  
Carcinoma Cells ◽  
Genital System ◽  
Diagnosis And Prognosis ◽  
Male Genital System ◽  
Morphological Differences ◽  
Hormone Imbalance ◽  
Made In ◽  
Male Genital

The most frequently occuring abnormality of the male genital system in mammals is the failure of one or both testes to descend into the scrotum. The reasons for abdominal or inguinal retention of testes could be anatomic malformation, faulty development or hormone imbalance.Cryptorchidism has been associated with either greatly reduced or absent spermatogenesis (Kaueakami et al, 1984), and being a source of neoplasia. According to Stick (1980), germinal carcinoma cells have been believed to be the cause of teratomas in equine cryptorchid testicles. Neoplasia has been reported in descended testes of unilateral cryptorchid patients (Martin et al, 1981).No distinction has been made in relating the problem of cryptorchid testes to inguinal or abdominal retention. The purpose of this study is to record the morphological differences between inguinal and abdominal cryptorchid testes as an aid in diagnosis and prognosis.

Biomedical applications: Pitfalls in the practice

1994 ◽  
Vol 52 ◽  
pp. 378-379
Author(s):  
J. D. Shelburne ◽  
Peter Ingram ◽  
Victor L. Roggli ◽  
Ann LeFurgey
Keyword(s):  
Operating Room ◽  
Liquid Nitrogen ◽  
Lung Tissue ◽  
Biomedical Applications ◽  
Microprobe Analysis ◽  
Tissue Sample ◽  
Cellular Level ◽  
Tissue Samples ◽  
Asbestos Fibers

At present most medical microprobe analysis is conducted on insoluble particulates such as asbestos fibers in lung tissue. Cryotechniques are not necessary for this type of specimen. Insoluble particulates can be processed conventionally. Nevertheless, it is important to emphasize that conventional processing is unacceptable for specimens in which electrolyte distributions in tissues are sought. It is necessary to flash-freeze in order to preserve the integrity of electrolyte distributions at the subcellular and cellular level. Ideally, biopsies should be flash-frozen in the operating room rather than being frozen several minutes later in a histology laboratory. Electrolytes will move during such a long delay. While flammable cryogens such as propane obviously cannot be used in an operating room, liquid nitrogen-cooled slam-freezing devices or guns may be permitted, and are the best way to achieve an artifact-free, accurate tissue sample which truly reflects the in vivo state. Unfortunately, the importance of cryofixation is often not understood. Investigators bring tissue samples fixed in glutaraldehyde to a microprobe laboratory with a request for microprobe analysis for electrolytes.

Sign in / Sign up

Export Citation Format

Share Document