Small Increments of a Trajectory

2021 ◽  
pp. 117-126
Author(s):  
Leonid T. Ashchepkov ◽  
Dmitriy V. Dolgy ◽  
Taekyun Kim ◽  
Ravi P. Agarwal
Keyword(s):  
2014 ◽  
Vol 29 (3/4) ◽  
pp. 237-260 ◽  
Author(s):  
Ashutosh Dixit ◽  
Kenneth D. Hall ◽  
Sujay Dutta

Purpose – The purpose of this paper is to investigate the influence of price attribute framing and factors such as urgency and perceived price fairness on customer willingness to pay (WTP) in automated retail settings. Design/methodology/approach – The authors conducted two sets of quasi-experimental scenarios surrounding vending-machine purchase decisions. The first set was analyzed with MANOVA, the second set with choice-based conjoint (CBC) analysis. Findings – When prices are framed positively (as a discount), customer WTP is higher at high published price levels than it is for unframed or negatively framed prices. The effect on WTP holds whether the reference price range is broad (few large increments) or narrow (numerous small increments). In the CBC scenarios, immediate availability of the product was most influential on choice, followed by price and brand effects. These findings held under conditions invoking both urgency and price fairness. Providing an explanation for higher prices increases perceived price fairness. Research limitations/implications – Further study might assess the presence or absence of interaction effects in the conjoint scenarios. Practical implications – Managers should consider transparency in dynamic pricing, particularly when the price change is outside the control of the firm. The conjoint scenario results also offer evidence that dynamic pricing will not impact other marketing-mix decisions for fast-moving consumer goods (FMCG) dramatically (availability at point of purchase and presence in the consumer consideration set remain strong influences on choice). Social implications – Understanding these effects on WTP could help managers manage perceptions of unfairness and optimize WTP. Originality/value – A theoretical contribution from this study is that the immediate loss/gain consideration under theories of decision making under uncertainty outweigh considerations such as scarcity urgency or perceived unfairness. Use of conjoint analysis in WTP research, study of dynamic pricing in FMCG setting.


1984 ◽  
Vol 67 (6) ◽  
pp. 613-618 ◽  
Author(s):  
B. F. Robinson ◽  
R. J. W. Phillips

1. The effect of a small increase in local plasma calcium concentration on the responsiveness of the forearm resistance vessels to verapamil has been examined in normal subjects, by using a plethysmographic method with infusion of calcium and other agents into the brachial artery. 2. Infusion of calcium at a rate which increased the concentration in forearm venous blood by about 0.5 mmol/l caused basal blood flow to fall by 19% and the dilator response to verapamil to fall by 35% (n = 8; P<0.02). 3. When, after 46 min, the infusion of calcium was discontinued, the dilator response to verapamil increased to reach a level 53% higher than the initial control (n = 8; P<0.02). 4. Infusion of calcium had no effect on the dilator response to sodium nitroprusside. 5. Infusion of noradrenaline at a rate which caused a greater reduction in basal flow than that induced by calcium had no effect on the response to verapamil. 6. It is concluded that the dilator response to verapamil, which is thought to reflect activity of the potential operated system for calcium entry, is selectively depressed by a small elevation of plasma calcium concentration, but subsequently becomes elevated. These findings point to an important role for calcium in the regulation of membrane function in the resistance vessels and support the view that altered calcium handling may contribute to the development of primary hypertension.


2012 ◽  
Vol 525-526 ◽  
pp. 17-20
Author(s):  
P.H. Wen ◽  
M.H. Aliabadi

This paper presents a new fatigue crack growth prediction by using the dimensional reduction methods including the dual boundary element method (DBEM) and element-free Galerkin method (EFGM) for two dimensional elastostatic problems. One crack extension segment, i.e. a segment of arc, is introduced to model crack growth path. Based on the maximum principle stress criterion, this new prediction procedure ensures that the crack growth is smooth everywhere except the initial growth and the stress intensity factor of mode II is zero for each crack extension. It is found that the analyses of crack paths using coarse/large size of crack extension are in excellent agreement with analyses of the crack paths by the tangential method with very small increments of crack extension.


Author(s):  
E C Attwood ◽  
G E Atkin

The thyroxine: thyroxine-binding globulin (T4: TBG) ratio is now an established part of the biochemical investigation of thyroid function. Reference ranges have been reported for euthyroid subjects with TBG levels within the range 6–16 mg/l. Routine assay of TBG on all thyroid function tests in this laboratory has suggested that, in patients with low or high TBG levels, the established reference ranges for T4:TBG may not be strictly applicable. A retrospective study has been made of a large number of thyroid function requests, including serum total T4, free T4, TBG, and TSH assays. Evidence is presented to show that in subjects with a TBG level of less than 8 mg/l the reference range for T4: TBG is elevated. Similarly, in subjects with a TBG greater than 16 mg/l, the reference range for T4: TBG is lowered. The data suggest that it is necessary to quote a T4: TBG reference range based on small increments of TBG levels or to relate total T4 reference ranges to those increments.


2007 ◽  
Vol 129 (3) ◽  
pp. 440-445 ◽  
Author(s):  
Gary S. Schajer

An effective procedure is presented that allows stable hole-drilling residual stress calculations using strain data from measurements taken at many small increments of hole depth. This use of many strain measurements is desirable because it improves the data content of the calculation, and the statistical reliability of the residual stress results. The use of Tikhonov regularization to reduce the noise sensitivity that is characteristic of a fine-increment calculation is described. This mathematical procedure is combined with the Morozov criterion to identify the optimal amount of regularization that balances the competing tendencies of noise reduction and stress solution distortion. A simple method is described to estimate the standard error in the strain measurements so that the optimal regularization can be chosen automatically. The possible use of a priori information about the trend of the expected solution is also discussed as a further means of improving the stress solution. The application of the described method is demonstrated with some experimental measurements, and realistic results are obtained.


Hypertension ◽  
2013 ◽  
Vol 62 (suppl_1) ◽  
Author(s):  
Wanzhu Tu ◽  
Hai Liu ◽  
George Eckert ◽  
J Howard Pratt

Aldosterone contributes to the elevation of blood pressure (BP) by acting on the distal tubule to cause greater sodium retention and volume expansion. Blacks, in comparison with whites, have lower plasma aldosterone concentrations (PAC), possibly due to increased sodium reabsorption and resultant renin suppression, as evidenced by their lower plasma renin activity (PRA); but BP is on average higher in blacks. The seemingly different BP-PAC relationships in blacks and whites raise point to the possibility of different aldosterone sensitivity in the two race groups. Using data from a cohort of normotensive youths (n=654 observations contributed by 537 subjects), we used a varying coefficient model to examine the BP effect of PAC at different levels of PRA in blacks and whites. We characterized the effects of PAC as a function of PRA and assessed its effect on age, sex, and height-adjusted BP percentile. The estimated effects are presented graphically (Figure 1 a&b). Blacks had lower PRA and PAC (PRA: 2.8 vs 3.3, p=0.002; PAC: 8.7 vs 14.1, p<0.0001; PAC/PRA: 4.7 vs 5.4, p=0.172), and marginally higher systolic and diastolic BP percentiles (SBP%: 44.5 vs 40.6, p=0.082; DBP%: 57 vs 51, p=0.004). In blacks, the BP effect of PAC was much greater in blacks at lower PRA levels (p=0.004); in whites, PAC effect on BP was not significant (p=0.164) and the effect did not change noticeably with PRA. In conclusion, the finding supports the notion that blacks have higher levels of aldosterone sensitivity, especially for those with lower PRA. A sustained state of volume expansion appears to make blacks vulnerable to the BP effects of even small increments in sodium retention produced by aldosterone.


1975 ◽  
Vol 35 (1) ◽  
pp. 120 ◽  
Author(s):  
Carl S. Apstein ◽  
Marc Mueller ◽  
Lawrence Deckelbaum ◽  
William B. Hood

1990 ◽  
Vol 258 (5) ◽  
pp. R1279-R1285 ◽  
Author(s):  
C. J. Charles ◽  
E. A. Espiner ◽  
V. A. Cameron ◽  
A. M. Richards

The integrative and sustained effects of small increments in atrial natriuretic factor (ANF) on hemodynamic, renal, and hormonal function are still unclear. Accordingly, we have studied the sequential effects of 24-h, low-dose infusion (2.4 pmol.kg-1.min-1) of rat Ile-ANF or vehicle alone (control) in six normal sheep receiving a constant sodium intake. Compared with control observations, ANF infusions induced a threefold rise in venous plasma ANF and a sustained twofold rise in plasma guanosine 3',5'-cyclic monophosphate. Systolic arterial and right atrial pressures fell promptly and remained significantly reduced for the duration of the ANF infusions. These changes were associated with a sustained fall in plasma volume but no activation of renin-angiotensin-aldosterone system. In contrast to the other actions, ANF-induced natriuresis, which was significant in the first 8 h of infusion, was not sustained. These studies show that significant biological effects occur in response to small ANF increments (20-25 pmol/l) and indicate that hemodynamic factors, especially fall in plasma volume, are important in determining the renal response even at near-normal plasma ANF concentrations.


2012 ◽  
Vol 4 (1) ◽  
pp. 76-124
Author(s):  
Michael Kimmel

Abstract The article explores the prerequisites of embodied ‘conversations’ in the improvisational pair dance tango argentino. Tango has been characterized as a dialog of two bodies. Using first- and second-person phenomenological methods, I investigate the skills that enable two dancers to move as a super-individual ensemble, to communicate without time lag, and to feel the partner’s intention at every moment. How can two persons - walking in opposite directions and with partly different knowledge - remain in contact throughout, when every moment can be an invention? I analyze these feats through the lens of image schemas such as BALANCE, FORCE, PATH, and UP-DOWN (Johnson 1987). Technique-related discourse - with its use of didactic metaphor - abounds with image-schematic vectors, geometries, and construal operations like profiling. These enable the tango process: from posture, via walking technique and kinetics, to attention and contact skills. Dancers who organize their muscles efficiently - e.g., through core tension - and who respect postural ‘grammar’ - e.g., a good axis - enable embodied dialog by being receptive to their partners and being manoeuvrable. Super-individual imagery that defines ‘good’ states for a couple to stick to, along with relational attention management and kinetic calibration of joint walking, turns the dyad into a single action unit. My further objective is a micro-phenomenological analysis of joint improvisation. This requires a theory to explain dynamic sensing, the combining of repertory knowledge with this, and the managing of both in small increments. Dancers strategically sense action affordances (Gibson 1979) or recognize and exploit them on the fly. Dynamic routines allow them to negotiate workable configurations step-wise, assisted by their knowledge of node points where the elements of tango are most naturally connected and re-routed. The paper closes with general lessons to learn from these highly structured and embodied improvisational skills, especially regarding certain blind spots in current social cognition theory.


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