Anatomical variants and LDBE

Background and purpose Information on the association between anatomical variants of the Circle of Willis (CoW) and intracranial atherosclerotic disease (ICAD) is limited and results are controversial. In this population-based study, we aimed to assess whether an incomplete CoW is associated with high calcium content in carotid siphons (a reliable biomarker of ICAD) in community-dwelling older adults of Amerindian ancestry. Methods Individuals aged ≥60 years enrolled in the Three Villages Study received a head computed tomography (CT) and magnetic resonance angiogram (MRA) of intracranial vessels. The CoW was classified in complete or incomplete according to the presence or absence of one A1 segment of the anterior cerebral artery or one or both P1 segments of posterior cerebral arteries. Calcium content in carotid siphons was rated as low or high. A multivariate logistic model was fitted to assess the independent association between incompleteness of the CoW and high calcium content in carotid siphons, after adjusting for demographics and cardiovascular risk factors. Results A total of 581 individuals were enrolled (mean age: 71 ± 8.4 years; 57% women). MRA revealed an incomplete CoW in 227 (39%) individuals, and high-resolution CT disclosed high calcium content in carotid siphons in 185 (32%). A risk factor logistic regression model showed no independent association between incompleteness of the CoW and high calcium content in carotid siphons (odds ratio: 0.91; 95% confidence interval: 0.62–1.34; p = 0.631). Conclusion Study results disclosed no association between anatomical variants of the CoW and the presence of high calcium content in carotid siphons.

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Anatomical Variants of Lister's Tubercle: A New Morphological Classification Based on Magnetic Resonance Imaging

Korean Journal of Radiology ◽

10.3348/kjr.2017.18.6.957 ◽

2017 ◽

Vol 18 (6) ◽

pp. 957 ◽

Cited By ~ 1

Author(s):

Wan Ying Chan ◽

Le Roy Chong

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Resonance Imaging ◽

Morphological Classification ◽

Anatomical Variants

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Anatomic variants of pulmonary venous drainage and their relation to recurrences of atrial fibrillation after pulmonary vein isolation

Bulgarian Cardiology ◽

10.3897/bgcardio.27.e71311 ◽

2021 ◽

Vol 27 (3) ◽

pp. 55-68

Author(s):

Svetla Dineva ◽

Milko Stoyanov ◽

Aneliya Partenova ◽

Boyan Kunev ◽

Victoria Stoyanova ◽

...

Keyword(s):

Pulmonary Vein ◽

Pulmonary Vein Isolation ◽

Local Population ◽

Venous Drainage ◽

Anatomical Variant ◽

Cox Regression Analysis ◽

Anatomical Variants ◽

The Impact ◽

Variant Anatomy ◽

Af Recurrence

Anatomical variants of pulmonary venous drainage in the left atrium are often found. Divergent results have been reported on the impact of variant anatomy on atrial ﬁ brillation (AF) recurrence after catheter ablation. We aimed to study the frequency of different anatomical variants of pulmonary venous drainage and their relationship with documented recurrences of AF after ablation. Material and methods: A retrospective study of patients with AF in whom radiofrequency pulmonary vein isolation was done after previously performed cardiac contrast-enhanced multidetector computed tomography. Clinical and procedural characteristics, type and frequency of anatomical variants of the veno-atrial junction and their association with AF recurrences were studied. Results: One hundred seventy-seven patients (112 men, 63.3%) with AF were studied, of which 148 (83.6%) with paroxysmal AF. Variant anatomy was found in 91 patients (51.4%). In 20.9% there was a common left trunk, in 23.2% – more or less than two right-sided veins, and in 7.3% – variations for both right and left veins. No differences in clinical and procedural characteristics were found between the groups with normal and variant anatomy. Recurrences of AF and their association with pulmonary venous anatomy were studied in 104 patients with follow-up ≥ 3 months. No signiﬁ cant relation was found between the presence of variant anatomy and AF recurrences within the blinding period after ablation, OR = 0.864, 95% CI = 0.397 – 1.88, p = 0.843, nor afterwards, OR = 1.12, 95% CI = 0.5 – 2.5, p = 0.839. Cox regression analysis showed no differences in AF recurrence-free survival regardless of the anatomical variant of pulmonary venous drainage, HR = 1.09, 95% CI = 0.58 – 2.05, p = 0.779. Conclusion: In this local population of patients with AF, the incidence of variant pulmonary venous drainage is just over 50%. No association was found between variant anatomy and the rate of AF recurrences after ﬁ rst pulmonary vein isolation.

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Prevalence of non-single canals in mandibular premolars and correlations with other anatomical variants: an in vivo cone beam computed tomography study

10.21203/rs.2.10416/v1 ◽

2019 ◽

Author(s):

Young-Eun Jang ◽

Yemi Kim ◽

Bom Sahn Kim ◽

Sin-Young Kim ◽

Hyung-Jong Kim

Keyword(s):

Computed Tomography ◽

Regression Analysis ◽

Cone Beam Computed Tomography ◽

Root Canal ◽

Odds Ratio ◽

Cone Beam ◽

Anatomical Variants ◽

Morphologic Characteristics ◽

Type V

Abstract Background A knowledge regarding anatomical variants is important to achieve success in endodontic treatment. Root canal treatment of mandibular first premolars (PM1s) is challenging due to the existence of numerous variations in canal configurations, including a C-shaped variant. We aim to determine the prevalence and morphologic characteristics of non-single canals of mandibular first (PM1s) and second (PM2s) premolars in a Korean population using cone beam computed tomography (CBCT) and to evaluate correlations between non-single canals of PM1s and other anatomical variants, such as distolingual roots (DLRs) in mandibular first molars (M1s) and C-shaped canals in mandibular second molars (M2s). Methods A total of 971 PM1s and 997 PM2s from 500 patients were examined in vivo by CBCT. Root canal configurations and C-shaped canals were determined in accordance with the Vertucci classification and Fan classification, respectively. The correlation between non-single canals in PM1s and DLRs in M1s was evaluated using logistic regression analysis. Results PM2s typically had one root (99.89%) with one canal (98.4%). Among PM1s with non-single canals (21.2%), Vertucci type V (10.9%) and C-shaped (3.7%) canals were prevalent. Among C-shaped PM1 canals, the majority were Vertucci type V (77.8%); a C-shaped configuration (C2) was predominant mostly at the middle and/or apical third of the root. After adjusting for other variables (i.e., sex, age, and side), C-shaped canals in PM1s was significantly correlated with the presence of DLRs in M1s (odds ratio = 2.616; 95% confidence interval, 1.257–5.443; p = 0.010). Conclusions The presence of C-shaped PM1 canals was positively related to the presence of DLRs in M1s. Although C-shaped canals in PM1s are difficult to distinguish, this finding could aid clinicians in predicting C-shaped canal configurations in PM1s of patients who exhibit DLRs in M1s.

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