Error Propagation Theory of Chemically Solid Phase Synthesized Oligonucleotides and DNA Sequences for Biomedical Application

1994 ◽  
pp. 165-173 ◽  
Author(s):  
Zeno Földes-Papp ◽  
Armin Herold ◽  
Hartmut Seliger ◽  
Albrecht K. Kleinschmidt
2019 ◽  
Vol 10 (45) ◽  
pp. 10481-10492 ◽  
Author(s):  
Marco Potowski ◽  
Florian Losch ◽  
Elena Wünnemann ◽  
Janina K. Dahmen ◽  
Silvia Chines ◽  
...  

DNA-encoded compound libraries are widely used in drug discovery. Screening of catalysts for compatibility with solid phase-coupled DNA sequences guided the selection of encoded reactions, exemplified by a Zn(II)-mediated aza-Diels–Alder reaction.


2019 ◽  
Vol 27 (2) ◽  
pp. 479-487
Author(s):  
屈也频 QU Ye-pin ◽  
侯 旺 HOU Wang

2015 ◽  
Vol 734 ◽  
pp. 572-576
Author(s):  
Qiao Fu Zhang ◽  
Xiao Qing Hu ◽  
Yan Jie Zhu ◽  
Ye Li

The error propagation theory and Monte Carlo simulations were employed to quantitatively evaluate the robustness of the saturated Turbo FLASH (Fast Low Angle SHot, satTFL) method. The uncertainty and probability density function (PDF) of the satTFL were derived. An out-of-phase method was introduced to correct flip angles larger than 90 degrees. Monte Carlo simulations were implemented to estimate the impact of Gaussian white noises in the image domain and thus the sensitivity could be visualized for different flip angles and signal to noise ratios (SNRs). The uncertainty, Monte Carlo simulations and experiments show that the satTFL is more precise for flip angles around 90 degrees.


1990 ◽  
Vol 4 (4) ◽  
pp. 285-297 ◽  
Author(s):  
Johan Wahlberg ◽  
Joakim Lundeberg ◽  
Thomas Hultman ◽  
Martin Holmberg ◽  
Mathias Uhlén

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