Multi-Modal Visualization of Probabilistic Tractography

2016 ◽  
pp. 195-218
Author(s):  
Mathias Goldau ◽  
Mario Hlawitschka
Keyword(s):  
Probabilistic Tractography

Functional MRI-guided probabilistic tractography of cortico-cortical and cortico-subcortical language networks in children

NeuroImage ◽  
2012 ◽  
Vol 63 (3) ◽  
pp. 1561-1570 ◽  
Author(s):  
Philip Julian Broser ◽  
Samuel Groeschel ◽  
Till-Karsten Hauser ◽  
Karen Lidzba ◽  
Marko Wilke
Keyword(s):  
Functional Mri ◽  
Probabilistic Tractography ◽  
Mri Guided

scholarly journals Deterministic and Probabilistic Tractography Based on Complex Fibre Orientation Distributions

2009 ◽  
Vol 28 (2) ◽  
pp. 269-286 ◽  
Author(s):  
M. Descoteaux ◽  
R. Deriche ◽  
T.R. Knosche ◽  
A. Anwander
Keyword(s):  
Fibre Orientation ◽  
Probabilistic Tractography ◽  
Orientation Distributions

Combining FDG-PET, structural MRI and probabilistic tractography in Alzheimer's disease

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S113
Author(s):  
SF Carter ◽  
GJM Parker ◽  
MA Lambon Ralph ◽  
K Herholz
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fdg Pet ◽  
Structural Mri ◽  
Probabilistic Tractography

scholarly journals Clinically Weighted Probabilistic Tractography Mapping of Therapeutic Thalamic Deep Brain Stimulation for Essential Tremor

Neurosurgery ◽  
2019 ◽  
Vol 66 (Supplement_1) ◽  
Author(s):  
Evangelia Tsolaki ◽  
Alon Kashanian ◽  
Nader Pouratian
Keyword(s):  
Deep Brain Stimulation ◽  
Clinical Outcome ◽  
Essential Tremor ◽  
Clinical Improvement ◽  
Brain Stimulation ◽  
Structural Connectivity ◽  
Precentral Gyrus ◽  
Probabilistic Tractography ◽  
Whole Brain ◽  
Deep Brain

Abstract INTRODUCTION Traditional targeting methods rely on indirect targeting with atlas-defined coordinates that induce interpatient anatomical and functional variability. Precise targeting is crucial for successful surgical intervention associated with improved surgical outcomes. Here, we use clinically weighted probabilistic tractography to investigate the connectivity from volume of tissue activated (VTA) to whole brain in order to evaluate the relationship between structural connectivity and clinical outcome of patients that underwent thalamic deep brain stimulation (DBS). METHODS Magnetic resonance imaging and clinical outcomes from 10 essential tremor (ET) patients who were treated by VIM-DBS at the University of California Los Angeles were evaluated. LeadBDS was used for the VTA calculation and FSL was used to evaluate the whole brain probabilistic tractography of VTA. Tractography maps were binarized and weighted based on the percent of clinical improvement using the Fahn-Tolosa-Martin Tremor Rating Score. The resulting clinically weighted maps were non-linearly fused to MNI space and averaged. These population maps provide a voxel-by-voxel map of the average clinical improvement observed when the VTA demonstrates structural connectivity to the whole brain. RESULTS The VTA connectivity to the whole brain was delineated. Superior clinical improvement was associated with connectivity to voxels connecting the thalamus to the precentral gyrus and to the brainstem/cerebellum. Also, the clinical efficacy map showed that patients with higher clinical improvement (>70%) presented stronger structural connectivity to the precentral gyrus and to the caudal projection to the cerebellum. CONCLUSION Stronger connectivity to the precentral gyrus and to brainstem/cerebellum is associated with superior clinical outcome in thalamic DBS for ET. In the future, rather than focusing on connectivity to predetermined targets, these clinically weighted tractography maps can be used with a reverse algorithm to identify the optimal region of the thalamus to provide clinically superior results.

scholarly journals Probabilistic tractography using Q-ball imaging and particle filtering: Application to adult and in-utero fetal brain studies

2013 ◽  
Vol 17 (3) ◽  
pp. 297-310 ◽  
Author(s):  
J. Pontabry ◽  
F. Rousseau ◽  
E. Oubel ◽  
C. Studholme ◽  
M. Koob ◽  
...  
Keyword(s):  
Particle Filtering ◽  
Fetal Brain ◽  
In Utero ◽  
Probabilistic Tractography
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