TD-NMR in Quality Control: Standard Applications

Shilajit has a longstanding use as an anti-aging and memory enhancing drug. It is known to have excellent anti-bacterial effects and is believed to be effective for cognitive enhancement, but is difficult to standardize because of the lack of quality control standards. This study, for the first time, proposes a quality control standard using a simultaneous analytical method for the drug’s multi-compound content using high-performance liquid chromatography-ultraviolet detection (HPLC-UV) as an aid for the internationalization of Mongolian Shilajit. Phenolic compounds 1-6 were isolated from Mongolian Shilajit extract using bioassay-guided isolation, and the isolated compounds were evaluated for cognitive-related anti-Alzheimer’s disease (AD) activities using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), β-site amyloid precursor protein-cleaving enzyme 1 (BACE1), and advanced glycation end-product (AGE) formation assays. The isolated compounds showed good effects for each activity. In addition, the isolated compounds were successfully quantified using a validated quantitative HPLC analysis method. As a result, the isolated compounds were suggested as standard marker compounds for Mongolian Shilajit. Also, we proved that the original material of Mongolian Shilajit is a lichen named Xanthoparmelia somloensis (Gyel.) Hale using HPLC-UV, ultra-high-performance liquid chromatography-electrospray ionization/hybrid linear trap-quadruple-orbitrap-high-resolution mass spectrometry (UHPLC-ESI/LTQ-HRMS).

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A Proposed Quality Control Standard Mixture and Its Uses for Evaluating Nontargeted and Suspect Screening LC/HR-MS Method Performance

Analytical Chemistry ◽

10.1021/acs.analchem.0c04036 ◽

2020 ◽

Author(s):

Ann M. Knolhoff ◽

Jacob H. Premo ◽

Christine M. Fisher

Keyword(s):

Quality Control ◽

Standard Mixture ◽

Method Performance ◽

Suspect Screening ◽

Quality Control Standard

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P-216. Quality control standard versus IVF-designed tissue-culture treated Petri dishes

Human Reproduction ◽

10.1093/humrep/14.suppl_3.249 ◽

1999 ◽

Vol 14 (Suppl_3) ◽

pp. 249-249

Author(s):

A. Lefebvre ◽

J. Van der Elst ◽

C. Qian ◽

M. Dhont

Keyword(s):

Tissue Culture ◽

Quality Control ◽

Quality Control Standard ◽

Petri Dishes

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A silicon metal quality-control standard preparation by means of collaborative trials of Brazilian laboratories

Accreditation and Quality Assurance ◽

10.1007/s00769-005-0032-5 ◽

2006 ◽

Vol 10 (12) ◽

pp. 681-685 ◽

Cited By ~ 1

Author(s):

Queenie Siu Hang Chui ◽

João Marcos de Almeida Bispo ◽

Celia Omine Iamashita

Keyword(s):

Quality Control ◽

Metal Quality ◽

Standard Preparation ◽

Quality Control Standard

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Quality Control Audit in the Republic of Tajikistan: Present Status and Perspective Standardization

Auditor ◽

10.12737/24736 ◽

2017 ◽

Vol 3 (2) ◽

pp. 49-54

Author(s):

Гоибназаров

Keyword(s):

Quality Control ◽

Present Status ◽

International Standards ◽

Quality Control Standard ◽

The Republic

The article describes the development and implementation of quality control standard auditor’s work in the Republic of Tajikistan based on the International Standards on Auditing.

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TD-NMR in Quality Control: Standard Applications

Modern Magnetic Resonance ◽

10.1007/978-3-319-28388-3_12 ◽

2018 ◽

pp. 1819-1836

Author(s):

Marcio Fernando Cobo ◽

Eleonore J. Deublein ◽

Agnes Haber ◽

Rance Kwamen ◽

Manoj Nimbalkar ◽

...

Keyword(s):

Quality Control ◽

Quality Control Standard

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Quality Control Framework for Statutory Audit of Financial Statements: A Comparative Study of USA, UK and India

Indian Journal of Corporate Governance ◽

10.1177/0974686216668458 ◽

2016 ◽

Vol 9 (2) ◽

pp. 186-211 ◽

Cited By ~ 1

Author(s):

Siddhartha Sankar Saha ◽

Mitrendu Narayan Roy

Keyword(s):

Quality Control ◽

The United States ◽

International Standards ◽

Control Policies ◽

Accounting Firms ◽

Quality Control Standard ◽

Policies And Procedures ◽

Control Framework ◽

The Usa ◽

The Uk

Quality control of audit procedure has become extremely important in today’s corporate environment in the backdrop of accounting irregularities and audit failures leading to corporate demise. Accounting firms control the quality of audit procedure with the help of the quality control standard (QCS) and specific auditing standard. These standards provide reasonable assurance of compliance with applicable regulation and issuance of the appropriate report by the engagement team. After discussing the international scenario of quality control framework, in this study a comparative analysis of quality control policies and procedures at firm and engagement in three select countries has been presented. The countries selected are the United States of America (USA), the United Kingdom (UK) and India. The study finds that the QCS and the auditing standard in all three countries are designed in line with International Standards on Auditing (ISAs) and International Standards on Quality Control (ISQC)-1. Naturally, quality control policies and procedures in three countries are comparable barring few minor differences. Based on these differences, it can be concluded that the quality control framework in the UK and India is more stringent as compared to the USA.

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PERANCANGAN SISTEM PENGENDALIAN KUALITAS PRODUK ASAM SULFAT (STUDI KASUS : PT. XYZ)

JURNAL TEKNIK INDUSTRI ◽

10.25105/jti.v5i3.1517 ◽

2017 ◽

Vol 5 (3) ◽

Author(s):

Juliani Sutikno

Keyword(s):

Quality Control ◽

Product Quality ◽

Sulphuric Acid ◽

Control Charts ◽

Quality Standard ◽

Raw Material ◽

National Standard ◽

Acid Product ◽

Quality Control Standard ◽

Product Specifications

PT. XYZ is a basic chemical manufacturing company which produces sulphuric acid. Quality standard are reffered to National Standard of Indonesia (SNI). PT. XYZ has certified the use of SNI standard for sulphurid acid product quality. Quality control of product is supervised by technician from PT. XYZ to ensure that only products that meet acceptable standard of quality which may be delivered to customer in order to ensure customer satisfaction. PT. XYZ establish product specifications sulphuric acid in the production process with a concentration of at least 98,5%. Determination of sulphuric acids product specification targets are too high from the referenced standard is loss and optimal quantity of product produced. This study aims to measure the process capability and product specifications of sulphuric acid establishes the right to increase the quantity of products. And then, Designing an appropriate system to control product quality sulphuric acid which has been determined. Determination of the specifications made by processing the sulphuric acids inspection levels. Processing data using analytical tools of quality control, histogram charts, control charts, and a causal diagram. Result of the analysis compared to the quality control standard established by BSN through SNI 0030:2011. From the comparison of the data will be used to set quality standard appropriate levels of sulphuric acid. Quality control system design sulphuric acid starts from the selection of raw material supplier, controlling during the setting process until the sulphuric acid concentration through dilution water.

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