Rathke Cleft Cyst

2020 ◽  
pp. 1-4
Author(s):  
M. Beatriz S. Lopes
Keyword(s):  
Rathke Cleft Cyst

scholarly journals Neuroendoscopic Transventricular Surgery for Suprasellar Cystic Mass Lesions Such as Cystic Craniopharyngioma and Rathke Cleft Cyst

2004 ◽  
Vol 44 (8) ◽  
pp. 408-415 ◽  
Author(s):  
Yukiko NAKAHARA ◽  
Hisao KOGA ◽  
Kenji MAEDA ◽  
Masashi TAKAGI ◽  
Kazuo TABUCHI
Keyword(s):  
Cystic Mass ◽  
Cystic Craniopharyngioma ◽  
Rathke Cleft Cyst ◽  
Mass Lesions

Differential Expression of Cytokeratins 8 and 20 Distinguishes Craniopharyngioma From Rathke Cleft Cyst

2002 ◽  
Vol 126 (10) ◽  
pp. 1174-1178 ◽  
Author(s):  
Wei Xin ◽  
Mark A. Rubin ◽  
Paul E. McKeever
Keyword(s):  
Molecular Weight ◽  
Differential Expression ◽  
Expression Patterns ◽  
Primary Diagnosis ◽  
Pars Intermedia ◽  
Rathke Cleft Cyst ◽  
Cytokeratin Expression ◽  
Pituitary Glands ◽  
Clinically Significant ◽  
Difficult Cases

Abstract Background.—Craniopharyngiomas are epithelial neoplasms usually located in the sellar and suprasellar regions. Distinguishing craniopharyngioma from Rathke cleft cyst is sometimes difficult, and the distinction is clinically significant because Rathke cleft cysts have a better prognosis than craniopharyngiomas. Design.—We retrieved 10 cases with a primary diagnosis of craniopharyngioma and 5 cases with a diagnosis of Rathke cleft cyst for analysis. Five cases of normal pars intermedia of pituitary glands from autopsy served as controls. We evaluated the expression patterns of a broad range of low– to intermediate–molecular weight cytokeratins (CK7, CK8, CK10, CK17, CK18, CK19, and CK20) and high–molecular weight cytokeratins (K903: a combination of CK1, CK5, CK10, and CK14; and CK5/6) in these cases. Results.—Craniopharyngiomas had a cytokeratin expression pattern distinct from that of Rathke cleft cysts and pituitary gland pars intermedia: craniopharyngiomas did not express cytokeratins 8 and 20, whereas Rathke cleft cysts and pars intermedia of pituitary glands both expressed cytokeratins 8 and 20. Conclusion.—The differential expression of cytokeratins distinguishes between craniopharyngioma and Rathke cleft cyst, and this difference could be useful for identifying craniopharyngioma in difficult cases in which only a small biopsy is available. The different cytokeratin profiles of craniopharyngioma and Rathke cleft cyst suggest that these lesions do not come from the same origin, or that they come from a different developmental stage of the pouch epithelium.

A Symptomatic Prolactinoma Coexisting Within a Rathke Cleft Cyst Invading Bone

2006 ◽  
Vol 16 (2) ◽  
pp. 91-94 ◽  
Author(s):  
Jordan L. Geller ◽  
Xuemo Fan ◽  
Veronica Arteaga ◽  
John Yu
Keyword(s):  
Rathke Cleft Cyst

scholarly journals Differentiation of Pituitary Adenoma from Rathke Cleft Cyst: Combining MR Image Features with Texture Features

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Yang Zhang ◽  
Chaoyue Chen ◽  
Zerong Tian ◽  
Yangfan Cheng ◽  
Jianguo Xu
Keyword(s):  
Pituitary Adenoma ◽  
Signal Intensity ◽  
Texture Features ◽  
Binary Logistic Regression ◽  
Image Features ◽  
Image Feature ◽  
Binary Logistic Regression Analysis ◽  
Mr Image ◽  
Rathke Cleft Cyst ◽  
Contrast Enhanced

Objectives. To differentiate pituitary adenoma from Rathke cleft cyst in magnetic resonance (MR) scan by combing MR image features with texture features. Methods. A total number of 133 patients were included in this study, 83 with pituitary adenoma and 50 with Rathke cleft cyst. Qualitative MR image features and quantitative texture features were evaluated by using the chi-square tests or Mann–Whitney U test. Binary logistic regression analysis was conducted to investigate their ability as independent predictors. ROC analysis was conducted subsequently on the independent predictors to assess their practical value in discrimination and was used to investigate the association between two types of features. Results. Signal intensity on the contrast-enhanced image was found to be the only significantly different MR image feature between the two lesions. Two texture features from the contrast-enhanced images (Histo-Skewness and GLCM-Correlation) were found to be the independent predictors in discrimination, of which AUC values were 0.80 and 0.75, respectively. Besides, the above two texture features (Histo-Skewness and GLCM-Contrast) were suggested to be associated with signal intensity on the contrast-enhanced image. Conclusion. Signal intensity on the contrast-enhanced image was the most significant MR image feature in differentiation between pituitary adenoma and Rathke cleft cyst, and texture features also showed promising and practical ability in discrimination. Moreover, two types of features could be coordinated with each other.

A Rare Case of Rapid Growth of a Rathke Cleft Cyst in an Adult Patient

2011 ◽  
pp. P1-441-P1-441
Author(s):  
Amit Seth ◽  
Nina Needleman ◽  
Agustin Busta
Keyword(s):  
Adult Patient ◽  
Rapid Growth ◽  
Rare Case ◽  
Rathke Cleft Cyst

Case of Acromegaly Caused by Rathke Cleft Cyst Mimicking Plurihormonal Pituitary Adenoma

2019 ◽  
Vol 126 ◽  
pp. 570-575
Author(s):  
Yusuke Morinaga ◽  
Kouhei Nii ◽  
Kimiya Sakamoto ◽  
Ritsurou Inoue ◽  
Takafumi Mitsutake ◽  
...  
Keyword(s):  
Pituitary Adenoma ◽  
Rathke Cleft Cyst ◽  
Plurihormonal Pituitary Adenoma

Endocrinopathy, Vision, Headache, and Recurrence After Transsphenoidal Surgery for Rathke Cleft Cysts

Neurosurgery ◽  
2010 ◽  
Vol 67 (3) ◽  
pp. 837-843 ◽  
Author(s):  
Scott D. Wait ◽  
Mark P. Garrett ◽  
Andrew S. Little ◽  
Brendan D. Killory ◽  
William L. White
Keyword(s):  
Rational Choice ◽  
Surgical Management ◽  
Transsphenoidal Surgery ◽  
Squamous Metaplasia ◽  
Senior Author ◽  
Visual Symptoms ◽  
Presenting Symptoms ◽  
Rathke Cleft Cyst ◽  
The Mean

Abstract BACKGROUND Rathke cleft cyst can enlarge and become symptomatic. OBJECTIVE To review the clinical data and results of all patients treated by the senior author for a Rathke cleft cyst. METHODS A prospectively maintained surgical database, supplemented with updates from telephone conversations, of all patients presenting to the Barrow Neurological Institute from 1992 to the present was reviewed. RESULTS Seventy-three patients (17 males, 56 females; mean age, 40 years; range, 5–80 years) underwent 77 resections. The mean length of follow-up was 27 months (range, 0–129 months). Presenting symptoms included headache (75%), followed by endocrinopathy (49%), and visual symptoms (39%). Preoperative chiasmopathy resolved in 75% and improved in 21% of the patients. Patients' preoperative endocrinopathy resolved at various rates, depending on the specific axis (29%–100%). Endocrinopathies were more likely to resolve in females than males. New postoperative endocrinopathies also occurred (0–8%). Headache resolved (68%) or improved (21%) in most patients. No patient had worsened headaches. Eight patients had a recurrence, 4 of whom underwent reoperation. The presence of squamous metaplasia was the only predictor of recurrence. CONCLUSION Surgical fenestration and/or resection of Rathke cleft cyst via the transsphenoidal approach are a rational choice for surgical management of these lesions when symptomatic. In most cases, visual symptoms and headache can be expected to improve. New persistent endocrine deficits can be expected in a small percentage of patients, but preexisting endocrinopathies resolve in many patients.

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