Oesophageal and Gastric Malignancy: Pictorial Atlas

2016 ◽  
pp. 91-130
Author(s):  
Anna Paschali ◽  
Teresa A. Szyszko
Keyword(s):  
Gastric Malignancy

Giant Solitary Gastric Peutz-Jeghers Polyp Mimicking a Malignant Gastric Tumor: the Largest Described in Literature

2014 ◽  
Vol 23 (3) ◽  
pp. 321-324 ◽  
Author(s):  
Sorinel Lunca ◽  
Vlad Porumb ◽  
Natalia Velenciuc ◽  
Dan Ferariu ◽  
Gabriel Dimofte
Keyword(s):  
Upper Gastrointestinal Bleeding ◽  
Rare Event ◽  
Gastric Tumor ◽  
Node Metastasis ◽  
Mucocutaneous Pigmentation ◽  
History Of ◽  
Peutz Jeghers Syndrome ◽  
Upper Gastrointestinal ◽  
Gastric Malignancy ◽  
Polypoid Tumor

A solitary Peutz-Jeghers polyp is defined as a unique polyp occurring without associated mucocutaneous pigmentation or a family history of Peutz-Jeghers syndrome. Gastric solitary localization is a rare event, with only eight reported cases to date. We report herein the case of a 43-year old woman who presented with upper gastrointestinal bleeding, severe anemia, weight loss and asthenia. Endoscopy revealed a giant polypoid tumor with signs of neoplastic invasion of the cardia, with pathological aspect suggesting a Peutz-Jeghers hamartomatous polyp. Computed tomography suggested a malignant gastric tumor and a total gastrectomy was performed. The pathological specimen showed a giant 150/70/50 mm polypoid tumor and immunochemistry established the final diagnostic of a Peutz-Jegers type polyp. This is the largest solitary Peutz-Jeghers gastric polyp reported until now, and the second one mimicking a gastric malignancy with lymph node metastasis.

scholarly journals Diagnostic utility of alarm features in predicting malignancy in patients with dyspeptic symptoms

2021 ◽  
Author(s):  
Anurag Shetty ◽  
Girisha Balaraju ◽  
Shiran Shetty ◽  
Cannanore Ganesh Pai
Keyword(s):  
Weight Loss ◽  
Epigastric Pain ◽  
Characteristic Curve ◽  
Abdominal Mass ◽  
Screening Tools ◽  
Disease Epidemiology ◽  
Dyspeptic Symptoms ◽  
Malignant Lesions ◽  
Alarm Features ◽  
Gastric Malignancy

Abstract Background Clinical features are of modest benefit in determining the etiology of dyspepsia. Dyspeptic patients with alarm features are suspected to have malignancy; but the proportions of patients and true cutoff values of various quantitative parameters in predicting malignancy are explored to a lesser extent. Methods This is a prospective observational study of consecutive patients undergoing esophagogastroduodenoscopy (EGD) for dyspeptic symptoms. Patients’ alarm features and clinical details were recorded in a predesigned questionnaire. The diagnostic accuracy of alarm features in predicting malignancy was studied. Results Nine hundred patients, 678 (75.3%) males, with a mean (standard deviation [SD]) age of 44.6 (13.54) years were enrolled. Commonest indication for EGD was epigastric pain in 614 (68.2%) patients. Dyspepsia was functional in 311 (34.6%) patients. EGD revealed benign lesions in 340 (37.8%) and malignancy in 50 (5.5%) patients. Among the malignant lesions, gastric malignancy was present in 28 (56%) and esophageal malignancy in 20 (40%) patients. Alarm features were present in 206 (22.9%), out of which malignant lesions were seen in 46 (22.3%) patients. Altogether, the alarm features had a sensitivity of 92% and specificity of 81.2% for predicting malignancy. The sensitivity and specificity for weight loss were 76% and 90.8%, while that of abdominal mass were 10% and 99.9% respectively. Based on receiver operating characteristic curve, the optimal age for screening of malignancy was 46.5 years in this population. Conclusions Patients of age group 40 to 49 years with dyspeptic alarm symptoms (predominant weight loss) need prompt endoscopy to screen for malignancy. The alarm features are inexpensive screening tools, found to be useful in India, and should be utilized in countries with similar healthcare conditions and disease epidemiology.

The Present Status of the Treatment of Gastric Malignancy

1953 ◽  
Vol 13 (6) ◽  
pp. 529-534
Author(s):  
Samuel F. Marshall
Keyword(s):  
Present Status ◽  
Gastric Malignancy

scholarly journals Gastric Angiomyolipoma Masquerading as Gastric Malignancy

2018 ◽  
Vol 5 (1) ◽  
pp. e96 ◽  
Author(s):  
Divya Achutha Ail ◽  
Roopa Rachel Paulose ◽  
Abhijit Kalitha ◽  
Annie Jojo ◽  
Unnikrishnan G
Keyword(s):  
Gastric Malignancy

Predictors of 30-day readmission rate after total gastrectomy in patients with gastric malignancy.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e16109-e16109
Author(s):  
Miguel Salazar ◽  
Estefania Gauto ◽  
Shristi Upadhyay Upadhyay Banskota ◽  
Pedro Palacios ◽  
Trilok Shrivastava ◽  
...  
Keyword(s):  
Total Gastrectomy ◽  
Economic Burden ◽  
Readmission Rate ◽  
Hospital Costs ◽  
Categorical Variables ◽  
Continuous Variables ◽  
Chi Square ◽  
Prolonged Length ◽  
Chi Square Test ◽  
Gastric Malignancy

e16109 Background: Total gastrectomy with lymph node dissection is curative for early gastric malignancy which accounts for 1.5% of cancer cases in the U.S. Readmissions are common postoperatively, and are associated with increased morbidity, mortality, hospital costs and decreased quality of life. We hence aim to identify incidence, impact and independent predictors for readmission in patients who underwent total gastrectomy in gastric malignancy. Methods: We conducted a retrospective cohort study of the 2017 National Readmission Database (NRD) of adult patients readmitted within 30 days after an index admission for total gastrectomy with a concomitant diagnosis of gastric malignancy. T-test was used for continuous variables and chi square test was used for categorical variables. Multivariate regression was used to identify predictors for unplanned readmissions. ICD 10 codes were used to identify diagnoses and procedures. Results: A total of 1,779 patients with gastric malignancy underwent total gastrectomy. The 30-day readmission rate was 18.5%. Main causes for readmission were sepsis, ventricular fibrillation, recurrent STEMI. Readmitted patients were more likely to be on chemotherapy. (40.1% vs 27.2%; P<0.01) and more likely to be discharged to a skilled facility (13.5% vs 17.9%; P<0.01). The total health care in-hospital economic burden of readmission was $6.5 million in total charges and $25 million in total costs. Independent predictors of readmission were major bleeding, respiratory failure requiring mechanical ventilation, peripheral parenteral nutrition, history of non-alcoholic hepato-steatosis, and prolonged length of stay. Conclusions: Readmissions after gastrectomy in patients with gastric malignancies are associated with lower in-hospital mortality yet pose a substantial economic burden on healthcare. The lower mortality might be explained by the relatively stable course and lower comorbidities of patients who become eligible for discharge after surgery. Further studies are suggested. Modifiable risk factors like malnutrition and sepsis warrant special attention to decrease readmissions and improve overall outcomes.[Table: see text]

scholarly journals Unusual case of adult familial Menetrier disease in siblings

2019 ◽  
Vol 12 (10) ◽  
pp. e231175
Author(s):  
Emily Brownson ◽  
Adrian J Stanley ◽  
Prakash Konanahalli ◽  
John P Seenan
Keyword(s):  
Family History ◽  
Iron Deficiency ◽  
Gastric Mucosa ◽  
Iron Deficiency Anaemia ◽  
Unusual Case ◽  
Gastric Epithelium ◽  
Deficiency Anaemia ◽  
History Of ◽  
Mucosal Folds ◽  
Gastric Malignancy

Menetrier disease is a rare disease characterised by hyperplasia of the gastric epithelium and large gastric folds. We present a case of a 58-year-old woman who was referred with iron deficiency anaemia, with a family history of a sibling who had undergone gastrectomy for presumed gastric malignancy. Endoscopy showed prominent gastric mucosal folds and biopsies showed hyperplastic gastric mucosa, with prominent foveolar hyperplasia suggestive of Menetrier disease. Further information about her brother’s diagnosis was sought, and it was found that his pathology after gastrectomy showed diffuse glandular hyperplasia also in keeping with Menetrier disease. Adult familial Menetrier disease has so far been a rarity in the literature—review elicits five previous cases of this presentation in siblings.

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