Molecular Forensics into the Sea: How Molecular Markers Can Help to Struggle Against Poaching and Illegal Trade in Precious Corals?

A key challenge for molecular biology is to use research outcomes to meet the demands of modern society. ‘Molecular forensics’ shows that molecular markers are having a substantial impact; from bench to boardroom or even courtroom. DNA profiling plays a role in helping to solve crimes and miscarriages of justice. Although 99.5 per cent of the human DNA sequence is the same for everyone, there are small regions of variability that are specific to each individual giving each person a unique DNA profile, or fingerprint. DNA profile applications are increasing and are now used to identify food counterfeits and contamination of food; to tackle pandemics and epidemics; and in biosecurity measures.

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Trawling the peripheral circulation for disseminating breast cancer cells and micrometastatic lymph node deposits using 3 new molecular markers: UROC28, CLSP and BCSG1

European Journal of Cancer ◽

10.1016/s0959-8049(02)80544-5 ◽

2002 ◽

Vol 38 (11) ◽

pp. S163

Author(s):

K Gomez

Keyword(s):

Breast Cancer ◽

Molecular Markers ◽

Lymph Node ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Peripheral Circulation

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CD44-9v and CD44-10v are potential molecular markers for squamous cell carcinoma of the vulva

Journal of the Society for Gynecologic Investigation ◽

10.1016/s1071-5576(99)00045-3 ◽

2000 ◽

Vol 7 (1) ◽

pp. 70-75 ◽

Cited By ~ 3

Author(s):

L Rodríguez-Rodríguez

Keyword(s):

Squamous Cell Carcinoma ◽

Molecular Markers ◽

Cell Carcinoma ◽

Squamous Cell

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Molecular Markers for Colorectal Cancer

Swiss Surgery ◽

10.1024/1023-9332.7.6.243 ◽

2001 ◽

Vol 7 (6) ◽

pp. 243-248

Author(s):

Scheunemann ◽

Hosch ◽

Kutup ◽

Izbicki

Keyword(s):

Colorectal Cancer ◽

Molecular Markers ◽

Prospektive Studien ◽

Therapeutische Konsequenzen

Die Einführung von immunhisto-/zytochemischen und molekularbiologischen bzw. zytogenetischen Methoden in der onkologische Forschung hat trotz vieler nach wie vor bestehender offener Fragen insgesamt zu einem besseren Verständnis der genetischen Ursachen der Tumorentstehung geführt. Darüber hinaus ergaben sich in verschiedenen Studien Hinweise für eine prognostische Relevanz von bestimmten (zyto)genetischen Veränderungen bzw. residualen Tumorzellen in Lymphknoten oder Knochenmark. Bevor diese Untersuchungen jedoch in den klinischen Alltag Einzug halten und therapeutische Konsequenzen abgeleitet werden können, sind weitere prospektive Studien mit groáen Patientenfallzahlen sowie vereinheitlichte und methodologisch praktikable Untersuchungstechniken zu fordern.

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