Prevention of Oxidative Stress by Omega-3 Fatty Acids in the Brain

2016 ◽  
pp. 239-249 ◽  
Author(s):  
Akhlaq A. Farooqui ◽  
Tahira Farooqui
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
The Brain

scholarly journals THE ROLE OF OXIDATIVE STRESS IN THE ETIOPATHOGENESIS OF DEPRESSION

2019 ◽  
Vol 17 (1) ◽  
pp. 81-93 ◽  
Author(s):  
D. Komsiiska ◽  
Y. Petkov
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Central Nervous System ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Cytotoxic Effects ◽  
Negative Effect ◽  
The Central Nervous System ◽  
The Brain

In recent years, the role of oxidative stress in the etiopathogenesis of depression has been increasingly discussed. The mechanisms by which stress has a negative effect on the brain are not yet fully understood. Free radicals cause rapid damage to certain cellular macromolecules that may be involved in cytotoxic effects in the central nervous system. The effectiveness of new types of supplementation therapy with antioxidants - vitamins A, E, C, Omega-3 fatty acids, Coenzyme Q10 and Zn are being studied.

Omega-3 fatty acids and mood stabilizers alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration

2016 ◽  
Vol 32 (2) ◽  
pp. 519-528 ◽  
Author(s):  
Lara M. Gomes ◽  
Milena Carvalho-Silva ◽  
Letícia J. Teixeira ◽  
Joyce Rebelo ◽  
Isabella T. Mota ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Mood Stabilizers ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

PP299 EFFECT OF ORAL SUPPLEMENTATION ENRICHED WITH OMEGA-3 FATTY ACIDS IN INFLAMATORY PARAMETERS AND OXIDATIVE STRESS IN PATIENTS WITH OTOLARYNGOLOGIST CANCER TREATED WITH RADIOTHERAPY

2010 ◽  
Vol 5 (2) ◽  
pp. 140 ◽  
Author(s):  
J.M. Garcia-Almeida ◽  
M. Murri-Pierri ◽  
Y. Lupiéñez ◽  
J.M. Rico-Pérez ◽  
H. Saracho-dominguez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oral Supplementation ◽  
And Oxidative Stress

scholarly journals Fructose, Omega 3 Fatty Acids, and Vitamin E: Involvement in Pediatric Non-Alcoholic Fatty Liver Disease

Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3531
Author(s):  
Gigliola Alberti ◽  
Juan Cristóbal Gana ◽  
José L. Santos
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Liver Disease ◽  
Vitamin E ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is currently the most common form of liver disease in both adults and children, becoming the leading cause for liver transplant in many countries. Its prevalence has increased considerably in recent years, mainly due to the explosive increase in pediatric obesity rates. NAFLD is strongly associated with central obesity, diabetes, dyslipidemia and insulin resistance, and it has been considered as the hepatic manifestation of the metabolic syndrome. Its complex pathophysiology involves a series of metabolic, inflammatory and oxidative stress processes, among others. Given the sharp increase in the prevalence of NAFLD and the lack of an appropriate pharmacological approach, it is crucial to consider the prevention/management of the disease based on lifestyle modifications such as the adoption of a healthy nutrition pattern. Herein, we review the literature and discuss the role of three key nutrients involved in pediatric NAFLD: fructose and its participation in metabolism, Omega-3 fatty acids and its anti-inflammatory effects and vitamin E and its action on oxidative stress.

Modulatory effect of cod-liver oil on Na+-K+ ATPase in rats’ brain

2010 ◽  
Vol 30 (4) ◽  
pp. 267-274 ◽  
Author(s):  
Taha A Kumosani ◽  
Said S Moselhy
Keyword(s):  
Fatty Acids ◽  
Atpase Activity ◽  
Cod Liver Oil ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Partial Restoration ◽  
Significant Depression ◽  
Cholinesterase Activities ◽  
The Impact ◽  
The Brain

Omega-3 fatty acids were used in the treatment of psychiatric diseases such as bipolar disorder. Na +, K+-ATPase is also a well-known target for these fatty acids. In this study, we investigated the impact of cod-liver oil (CLO), docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on Na+, K+-ATPase, cholinesterase activities, the levels of norepinephrine (NE) and acetylcholine in different regions of rat brain. Our results showed that DHA caused a significant depression in cerebellum Na+, K +-ATPase, whereas CLO activated it. In addition, CLO, EPA and DHA produced a significant activation in Na+, K+-ATPase activity in medulla, midbrain and hypothalamus. There were non-significant changes in the activity of cholinesterase enzyme in cerebellum and medulla, while in midbrain and hypothalamus the CLO, DHA and EPA enhanced the activity by 75%, 100% and 78%, respectively. The content of NE in hypothalamus showed slight increase in different regions of the brain of animals fed CLO, DHA or EPA. In conclusion, CLO, DHA or EPA supplementation had a beneficial effect that associated with a normalization of fatty acids incorporation into phospholipid membranes and a partial restoration of Na+, K+-ATPase activity, suggesting that CLO supplementation may improve fatty acid composition and moderately enhance Na+, K+-ATPase activity.

Omega 3 fatty acids and the brain: implications for nursing practice

2014 ◽  
Vol 10 (1) ◽  
pp. 29-37 ◽  
Author(s):  
Ashley Helvig ◽  
Michael Decker
Keyword(s):  
Fatty Acids ◽  
Nursing Practice ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
The Brain

Omega-3 fatty acids alter behavioral and oxidative stress parameters in animals subjected to fenproporex administration

2014 ◽  
Vol 29 (1) ◽  
pp. 185-192 ◽  
Author(s):  
Camila S. Model ◽  
Lara M. Gomes ◽  
Giselli Scaini ◽  
Gabriela K. Ferreira ◽  
Cinara L. Gonçalves ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters
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