Maternal Nutrition and Birth Outcomes

Author(s):  
Usha Ramakrishnan ◽  
Melissa Fox Young ◽  
Reynaldo Martorell
2020 ◽  
pp. 1-25
Author(s):  
Yidi Wang ◽  
Bradley A. Feltham ◽  
Michael N. A. Eskin ◽  
Miyoung Suh

Abstract Maternal nutrition status plays an important role in the development of fetal alcohol spectrum disorders (FASD), but its direct evidence is lacking. This study compared a standard chow with a semi-purified energy dense (E-dense) diet on birth and metabolic outcomes in rats after ethanol (EtOH) consumption during pregnancy. Pregnant Sprague-Dawley rats were randomized into four groups: chow (n=6), chow+EtOH (20% v/v) (n=7), E-dense (n=6), and E-dense+EtOH (n=8). Birth outcomes including litter size, body and organ weights were collected. Metabolic parameters were measured in dams and pups at postnatal day (PD) 7. Maternal EtOH consumption decreased body weights (p <0.0001) and litter sizes (p <0.05) in chow-fed dams. At PD7, pups born to dams fed E-dense diet had higher body (p <0.002) and liver weights (p <0.0001). These pups also had higher plasma total cholesterol (p <0.0001), triacyclglycerol (p <0.003) and alanine aminotransferase (p <0.03) compared to those from chow-fed dams. Dams fed E-dense diet had higher plasma total- (p <0.0001) and HDL-cholesterol (p <0.0001) and lower glucose (p <0.0001). EtOH increased total cholesterol (p <0.03) and glucose (p <0.05) only in dams fed the E-dense diet. Maternal exposure to E-dense diet attenuated prenatal EtOH-induced weight loss and produced different metabolic outcomes in both dams and pups. While the long-lasting effects of these outcomes are unknown, this study highlights the importance of maternal diet quality for maternal health and infant growth, and suggests that maternal nutrition intervention may be a potential target for alleviating FASD.


2016 ◽  
Vol 8 (2) ◽  
pp. 1-43 ◽  
Author(s):  
Verónica Amarante ◽  
Marco Manacorda ◽  
Edward Miguel ◽  
Andrea Vigorito

There is limited empirical evidence on whether cash transfers to poor pregnant women improve children's birth outcomes and potentially help weaken the cycle of intergenerational poverty. Using a unique array of program and social security administrative micro-data matched to longitudinal vital statistics in Uruguay, we estimate that participation in a generous social assistance program led to a sizable reduction in the incidence of low birthweight. The effect is due to faster intrauterine growth rather than longer gestational length. Our findings are consistent with improved maternal nutrition during pregnancy being a key driver of improved birthweight. (JEL I14, I32, I38, J13, J16, O15)


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 887-887
Author(s):  
Nandita Perumal ◽  
Mia Blakstad ◽  
Goodarz Danaei ◽  
Gunther Fink ◽  
Mark Lambiris ◽  
...  

Abstract Objectives Scaling-up nutrition interventions during pregnancy may provide human capital gains by lowering the risk of adverse birth outcomes associated with reduced long-term socioeconomic outcomes. We estimated gains in years of schooling and lifetime wages of scaling up prenatal maternal nutrition interventions for a 137 low- and middle-income countries. Methods Through a comprehensive review of the literature, we identified four prenatal maternal nutrition interventions with convincing-level of evidence for improving birth outcomes: prenatal multiple micronutrient supplements (MMS), calcium supplements, iron-folic acid supplements (IFA), and balanced protein energy supplements (BEP) among underweight pregnant women (BMI &lt; 18.5 kg/m2). Effect sizes for intervention impact were derived from systematic reviews and random-effects meta-analysis. We focused on low birthweight (LBW) and preterm birth (PTB) as primary birth outcomes. We used the 2015 LBW and PTB prevalence estimates to calculate country-specific absolute reductions attributable to scaling-up a given prenatal nutrition invention. We then used an effect size based on a de novo review of the economics literature to quantify gains in schooling and lifetime wages due to reductions in LBW/PTB under two hypothetical scale-up scenarios of 50% and 90% coverage. Results For each country, returns on schooling and lifetime wages were estimated for scaling-up each prenatal nutrition intervention. For example, in Bangladesh, scaling-up IFA supplements from current coverage of 26% to 90% was estimated to reduce LBW prevalence by 3.2% contributing to a predicted increase of 0.11 million school years and US$153 million in wages per birth cohort. Similarly, scaling-up MMS, calcium supplements, and BEP to 90% coverage was predicted to increase schooling by 0.25, 0.17, and 0.07 million years, and wages by US$338, US$223, and US$97 million, respectively, per birth cohort. Global, regional, and national-level estimates for schooling and wage gains for each nutrition intervention will be presented. Conclusions Our findings indicate that scaling-up prenatal maternal nutrition interventions will contribute to substantial population-level increases in human capital, particularly in countries with a high burden of low birthweight or preterm birth. Funding Sources Bill and Melinda Gates Foundation.


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Courtney Schnefke ◽  
Chessa Lutter ◽  
Faith Thuita ◽  
Albert Webale ◽  
Valerie Flax ◽  
...  

Abstract Objectives Eggs are nutrient-rich and have the potential to improve maternal nutrition during pregnancy and birth outcomes, but cultural beliefs may inhibit consumption during pregnancy. This study sought to understand pregnant women's and key influencers’ knowledge, attitudes, beliefs, and practices as well as facilitators and barriers related to consuming eggs during pregnancy in Kenya. Methods The study was conducted in an urban (Nairobi) and rural (Kiambu) area, had 3 phases and primarily used mixed qualitative methods to triangulate data. Phase I included in-depth interviews, 24-hour dietary recall, and free-listing and pile-sorting exercises with pregnant women (n = 36), husbands (n = 12) and mothers-in-law (n = 12) of pregnant women, and health workers (n = 24). Phase II involved egg preparation exercises with pregnant women (n = 39). Phase III involved a week-long trial of egg consumption with pregnant women (n = 24). We used thematic content analysis methods to analyze qualitative data and tabulated quantitative data. Results All participants recognized eggs as nutritious for pregnant women and their unborn children, though only 25% of pregnant women consumed eggs the previous day. Participants believed eating too many eggs during pregnancy (1 or more eggs daily) leads to a large baby and complications during delivery. Unaffordability and unavailability of eggs also inhibit consumption. Health workers are the most trusted source of information on maternal nutrition, while other pregnant and nonpregnant women in the community were cited as those who most often discourage egg consumption. Fried and boiled eggs are the most common and preferred preparation methods due to ease and limited number of ingredients. Almost all women complied with the household trial, said they would continue eating eggs during pregnancy, and would recommend consuming eggs in moderation to other pregnant women. Conclusions Although participants believed consuming eggs during pregnancy is beneficial, cultural norms, practices, and beliefs may prevent pregnant women from eating them daily. Interpersonal communication from health workers and agricultural policies to promote affordability could lead to increased consumption, which in turn could have potential positive impacts on maternal nutrition and birth outcomes. Funding Sources RTI International.


2010 ◽  
Vol 32 (1) ◽  
pp. 5-25 ◽  
Author(s):  
K. Abu-Saad ◽  
D. Fraser

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Nga Thuy Tran ◽  
Lam Thi Nguyen ◽  
Yatin Berde ◽  
Yen Ling Low ◽  
Siew Ling Tey ◽  
...  

Abstract Background During pregnancy, a mother’s nutritional needs increase to meet the added nutrient demands for fetal growth and development. An enhanced understanding of adequate nutrition and sufficient weight gain during pregnancy can guide development of policies and strategies for maternal nutrition care, actions that will ultimately promote better pregnancy outcomes. In a sample of pregnant women in Vietnam, this study characterized maternal nutrition status and gestational weight gain at a mid-pregnancy baseline, then examined the association of these variables with specific birth outcomes. Methods The study used baseline data from a randomized, controlled trial that compared pregnant Vietnamese women who received a nutritional intervention group with those who received only standard dietary counseling (control group). At baseline (26–29 weeks gestation), mothers’ dietary reports were collected, and intake of 10 macro- and micronutrients was estimated; data for baseline gestational weight gain was collected for all pregnant women enrolled into the study (n = 228). This analysis also used weights, lengths, and head circumferences at birth for infants of mothers in the control group. Results At baseline, 95% of the pregnant women had concurrent inadequacies for more than five nutrients, and nearly half had concurrent inadequacies for more than ten nutrients. Almost two-thirds of the pregnant women did not meet recommendations for gestational weight gain. We found a significant, inverse association between the number of nutrient inadequacies and gestational weight gain (overall p ≤ 0.045). After adjusting for potential confounders, gestational weight gain was positively associated with birth weight, length at birth, birth weight-for-age z-score and length-for-age z-score (all p ≤ 0.006). Conclusions Our findings raise concern over the high proportion of pregnant women in Vietnam who have multiple concurrent nutrient inadequacies and who fall short of meeting recommended gestational weight gain standards. To ensure better birth outcomes in this population, policies and strategies to improve the status of maternal nutrition are greatly needed. Trial registration The trial was retrospectively registered at clinicaltrials.gov on December 20, 2013, registration identifier: NCT02016586.


2012 ◽  
Vol 33 (2_suppl1) ◽  
pp. S6-S26 ◽  
Author(s):  
Cesar G. Victora ◽  
Fernando C. Barros ◽  
Maria Cecilia Assunção ◽  
Maria Clara Restrepo-Méndez ◽  
Alicia Matijasevich ◽  
...  

Background Maternal nutrition interventions are efficacious in improving birth outcomes. It is important to demonstrate that if delivered in field conditions they produce improvements in health and nutrition. Objective Analyses of scaling-up of five program implemented in several countries. These include micronutrient supplementation, food fortification, food supplements, nutrition education and counseling, and conditional cash transfers (as a platform for delivering interventions). Evidence on impact and cost-effectiveness is assessed, especially on achieving high, equitable, and sustained coverage, and reasons for success or failure Methods Systematic review of articles on large-scale programs in several databases. Two separate reviewers carried out independent searches. A separate review of the gray literature was carried out including websites of the most important organizations leading with these programs. With Google Scholar a detailed review of the 100 most frequently cited references on each of the five above topics was conducted. Results Food fortification programs: iron and folic acid fortification were less successful than salt iodization initiatives, as the latter attracted more advocacy. Micronutrient supplementation programs: Nicaragua and Nepal achieved good coverage. Key elements of success are antenatal care coverage, ensuring availability of tablets, and improving compliance. Integrated nutrition programs in India, Bangladesh, and Madagascar with food supplementation and/or behavioral change interventions report improved coverage and behaviors, but achievements are below targets. The Mexican conditional cash transfer program provides a good example of use of this platform to deliver maternal nutritional interventions. Conclusions Programs differ in complexity, and key elements for success vary with the type of program and the context in which they operate. Special attention must be given to equity, as even with improved overall coverage and impact inequalities may even be increased. Finally, much greater investments are needed in independent monitoring and evaluation.


2021 ◽  
Vol 10 (2) ◽  
pp. 15-19
Author(s):  
Naushaba Akhtar ◽  
Subhadarshini Satapathy

Background: The state of under nutrition among women in India has remained a prevalent cause for affecting maternal and child health and increasing neonatal deaths. Objective: In this paper, the authors have reviewed and summarized the complete knowledge of maternal nutrition requirements, how maternal nutrition impacts child health and public health considerations. Method: Review of existing scientific literature and records from the past. Conclusion: In this article, the author concludes that nutrition is one of those factors which can be easily modified and it is of great public health importance, giving importance to nutrition can be of great health to mother and child and reduce birth complications and adverse birth outcomes. Keywords: Nutrition, Maternal health, Maternal nutrition, Child Health, Birth outcomes.


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